ANAT41 - Lecture Outline CENTRAL NERVOUS SYSTEM - Spinal Cord PNS -Spinal Nerves Spinal cord Functions: 1. Conduction pathway 2. Reflex center Gross structure (a longitudinal view) Filum Terminale - the meningeal layers that anchor that spinal cord to the sacrum Cauda equina = collection of spinal nerves that hang below the spinal cord Conus medullaris = cone-shaped ending of the spinal cord Cervical and lumbar enlargements At what level of the vertebral column does the spinal cord terminate? 1 ANAT41 - Lecture Outline CENTRAL NERVOUS SYSTEM - Spinal Cord PNS -Spinal Nerves Meninges (connective tissue covering around the spinal cord and brain) Dura mater = superficial Arachnoid mater Pia mater = deepest; lies closest to the spinal cord Cross section (These structures can be viewed at a gross level. However, they are easier to see at the microscopic level.) 1. Central canal = where CSF flows 2. Gray matter = collection of cell bodies, dendrites, and unmyelinated axons anterior, posterior and lateral horns commissure 3. White matter = myelinated axons arranged in columns 4. Spinal nerves a. Dorsal root b. Dorsal root ganglion =bundle of cell bodies in PNS c. Ventral root 2 ANAT41 - Lecture Outline CENTRAL NERVOUS SYSTEM - Spinal Cord PNS -Spinal Nerves Conduction pathways (spinal tracts) 1. Ascending (sensory) tracts 2. Descending (motor) tracts 3 ANAT41 - Lecture Outline CENTRAL NERVOUS SYSTEM - Spinal Cord PNS -Spinal Nerves Spinal nerves Function - All are mixed nerves. They carry both sensory and motor fibers. Number - 31 pairs (total of 62 spinal nerves) 1. Cervical - 8 pairs 2. Thoracic - 12 pairs 3. Lumbar - 5 pairs 4. Sacral - 5 pairs 5. Coccygeal - 1 pair Structure 1. Roots a. Dorsal root - sensory fibers b. Ventral root- motor fibers 2. The two roots unite to form each spinal nerve and it passes through the intervertebral foramen. Plexuses Main portions of spinal nerves form plexuses (networks of nerve fibers) in all regions but the thoracic region. Nerves emerge from these plexuses. 1. Cervical plexus a. Most nerves from this plexus go to the skin and muscles of the head, neck and shoulders. b. MAJOR NERVES: R & L phrenic nerves - Fibers from C3-C5 nerves form phrenic nerves. Supply diaphragm. 2. Brachial plexus a. Branches from this plexus go to the upper limb. b. MAJOR NERVES: Ulnar and radial nerves - Supply arm, forearm and hand. (Ulnar nerve passes between medial epicondyle and olecranon process = funny bone). 3. Intercostal nerves (T1-T11) a. Emerge from thoracic region. No plexuses. b. Supply intercostal muscles. 4. Lumbosacral plexus a. Branches from this plexus go to the lower abdominal wall and and the lower extremity. b. MAJOR NERVES: 1) R & L femoral nerves- Supply anterior thigh (Quadriceps femoris, Sartorius) 2) R & L Sciatic nerve - Supply posterior thigh (Hamstrings) and anterior and posterior leg (Gastrocnemius) plus foot. 4 ANAT41 - Lecture Outline CENTRAL NERVOUS SYSTEM - Spinal Cord PNS -Spinal Nerves Reflex center What Is a reflex? Fast, unplanned, automatic sequence of actions that occur in response to a stimulus They can be spinal or cranial in location, and somatic and autonomic in function Components of spinal reflex arc: 1. 2. 3. 4. 5. Receptor Sensory (afferent) neuron Interneuron Motor (efferent) neuron Effector 5 ANAT41 - Lecture Outline CENTRAL NERVOUS SYSTEM - Spinal Cord PNS -Spinal Nerves Examples of spinal reflexes: (We will perform some of these in lab.) a. Withdrawal reflex b. Patellar reflex 6 ANAT41 - Lecture Outline CENTRAL NERVOUS SYSTEM - Spinal Cord PNS -Spinal Nerves c. Corneal reflex 7