INTERACTIVE NOTEBOOK GUIDELINES
Pencil ONLY
 Name, class, period on cover
 1st page upper right corner put an A (free corner)
 Letter pages A-F (front AND back of page)
 Page “1” of numbering starts on 4th page of Notebook
 Go ahead and # 1-20 on top free corner of notebook
 Each page should have title unless noted otherwise

COVER
PAGE A <TITLE PAGE>
INTERACTIVE NOTEBOOK GUIDELINES

C-F Table of Contents
Page Title
1-3 Roots, Prefixes, Suffixes
4
Biology lab safety rules
5
Safety Symbols
6-7 Safety Contract
8
Classroom Layout
9
Lab Safety Equipment Scavenger Hunt
10-11 Lab Equipment
12 Scientific Method Vocabulary
13 Data Graphing
PAGE B <BLANK>
PAGE C <TABLE OF CONTENTS>
PAGE D <TABLE OF CONTENTS>
PAGE E <TABLE OF CONTENTS>
PAGE F <TABLE OF CONTENTS>
PAGE 1 <ROOTS, PREFIXES AND SUFFIXES>
PAGE 2 <ROOTS, PREFIXES AND SUFFIXES>
PAGE 3 <ROOTS, PREFIXES AND SUFFIXES>
PAGE 4 <BIOLOGY LAB SAFETY RULES>
PAGE 5 <SAFETY SYMBOLS>
PAGE 6-7 <SCIENCE SAFETY CONTRACT>
PAGE 8 <CLASSROOM LAYOUT>
PAGE 9 <LAB CLASSROOM SCAVENGER HUNT>
LAB EQUIPMENT FOR SCAVENGER
Fire blanket
 Shower
 First Aid kit
 Aprons
 Eyewash station
 Goggles
 Fire Extinguisher

PAGE 10 <LAB EQUIPMENT>
PAGE 11 <LAB EQUIPMENT>
PAGE 12 <SCIENTIFIC METHOD VOCABULARY>
PAGE 13 <DATA GRAPHING>
PAGE 13
<DATA GRAPHING>
D- Dependent variable
R- Responding variable
Y- y-axis
M- Manipulated variable
I- Independent Variable
X- x-axis
ALWAYS INCLUDE UNITS!
PAGE 14 <CHARACTERISTICS OF LIVING THINGS>

List all 8
characteristics
and draw
picture to go
with them
(must color!)
PAGE 15 <HIERARCHY OF MULTICELLULAR
ORGANISMS>
1.
2.
3.
4.
5.
6.
Chemical Level- Atoms combine to form molecules
Cellular Level- Cells are made of molecules
Tissue Level- Consist of similar types of cells
Organ Level- Made of different types of tissue
Organ System- Consists of organs that work together
Organism- Made of many organ systems that function to
keep us alive
PAGE 15 <HIERARCHY OF MULTICELLULAR
ORGANISMS>
PAGE 14 <CHARACTERISTICS OF LIVING THINGS>
PAGE 15 <HIERARCHY OF MULTICELLULAR ORGANISMS>
PAGE 16 <SCIENTIFIC METHOD FLOWCHART>
I. Observation(s)
o Using your 5 senses to gain information about the
problem/experiment
o Sound, Sight, Hear, Touch, Taste
o Noting facts or inferences
Descriptions
o Qualitative (__________)
or Quantitative (__________)
Numbers
(ex: color, smell)
(can be measured)
o List of Materials
o What is the question or
problem you want to answer?
The Scientific Method
2. Hypothesis
o A probable prediction based on your observations;
your educated prediction
o Must be something testable
o Can be in an “If…., then…..” statement
3. Experiment:
o To be a valid experiment, it must
o Be a controlled experiment
o Test only one variable at a time
o Be repeated numerous times
o Use random sampling
o Use accurate records & measurements
o Must be a controlled experiment.
o Control = the norms to compare the thing being tested against; does
not change
o Variable = the thing that changes; the thing being tested
Independent
 ____________
variable being acted upon; changed on
purpose
Independent
Dependent
 ____________
variable that changes because the ____
Controlled
 ____________
variable stays the same; does not change
o State the purpose of the experiment in
 “To determine…..” format
o List the steps of the experiment; Betty Crocker Style
o Step #1…Gather materials
o End step…Record data
o No 1st person
o One action per #
o Be clear & concise
4. Data:
o Tables where data was recorded
o Illustrations of experiment
o Accurate, precise data graphs to present
findings***
o Label all data & units!
5. Conclusion:
o Restate hypothesis
o Brief summary of what you did in the
experiment
o Was hypothesis right/wrong? Why/why not
o Problems encountered
o Ideas/suggestions for future experimenters
PAGE 17 <PERIODIC TABLE- ELEMENTS OF LIFE>
Glue in Periodic Table
Highlight corresponding colors
PINK
YELLOW
 Oxygen (65%)
Phosphorus (P)
 Carbon (18%)
Sulfur (S)
 Hydrogen (10%)
Calcium (Ca)
 Nitrogen (3%)
Iron (Fe)
somewhere on page put: Potassium (K)
Sodium (Na)
NOCH=96%
PAGE 16 <SCIENTIFIC METHOD FLOWCHART>
PAGE 17 <PERIODIC TABLE- ELEMENTS OF LIFE>
PAGE 18 <PROPERTIES OF WATER>

Add to diagram: δ+ and δ- on all atoms and
show Hydrogen bonds (- - -)
Color
Oxygen=yellow
Hydrogen=green
Hydrogen Bonds=blue
Universal _____________
 Polar- (define)
 Hydrogen Bonds:
 Cohesion- (define; example)
 Adhesion- (define; example)
 Ice Floats, Heat of vaporization (sweat), High Specific Heat

PAGE 18 <PROPERTIES OF WATER>

Add to diagram: δ+ and δ- on all atoms and
show Hydrogen bonds (- - -)
δ+
δ+
δ+
δ+
δδ+
δ-
δ+
Color
Oxygen=yellow
Hydrogen=green
Hydrogen Bonds=blue
δ
Universal Solvent-dissolves many substances

Polar- Unequal sharing of electrons; results in partial + and partial - sides

Hydrogen Bonds:
 Cohesion- attraction of like molecules (rainsdrop, surface tension)
 Adhesion- attraction of unlike molecules (water on web, meniscus)
 Capillary Action-Ice Floats, Heat of vaporization (sweat), High Specific Heat
PAGE 19 <MACROMOLECULES>
 Monomer-1
 Polymer-
sub-unit
multiple units
 Formation
of Polymers- Polymerization,
Dehydration Synthesis, Condensation
Reaction
 Removal
of water molecule
to form covalent bond
 H=green, O= yellow
4

groups of Macromolecules (list)
Carbohydrates, Lipids, Nucleic Acids, Proteins
PAGE 18 <PROPERTIES OF WATER>
PAGE 19 <MACROMOLECULES>
PAGE 20 <CARBOHYDRATES>
Glue in image set
Elements: C, H, O 1:2:1 ratio
 Monomer: Monosaccharide (glucose, fructose, galactose)
 Polymers: Disaccharide (2) Polysaccharide (many)
 Examples: cellulose, glycogen, starch
 Function: Short term energy storage and building
material
 Food source: Pasta, bread, fruit, potatoes

PAGE 21 <LIPIDS>
Glue in image set
Elements: C, H, O
 Monomers: Fatty acid chains, glycerol
 Polymers: Fats/Oils, Phospholipids, Steroids
 Examples: phospholipid, oil, ear wax
 Function: Long term energy storage,
insulation, cushioning, waterproof
 Food Source: Oils, butter, animal fat

PAGE 20 <CARBOHYDRATES>
PAGE 21 <LIPIDS>
PAGE 22 <NUCLEIC ACIDS>
Glue in image set
Elements: C, H, O, N, P
 Monomer: Nucleotide (sugar, phosphate, nitrogenous
base)
 Polymers: DNA and RNA
 Examples: RNA, DNA, (ATP-single unit)
 Function: Genetic instructions and usable energy
 No Food Source

PAGE 23 <PROTEINS>
Glue in image set
Elements: C, H, O, N
 Monomer: Amino Acid
 Polymer: Polypeptide chain
 Examples: hair, nails, muscles, enzymes
 Function: Storage, transport, regulation,
movement, structure, enzymes
 Food Source: Meat, peanut, egg

PAGE 22 <NUCLEIC ACIDS>
PAGE 23 <PROTEINS>
PAGE 24 <ENZYMES>
 Proteins
that catalyze (speed up) reactions by
lowering the activation energy
 Common Features
1.
2.
3.
4.
Work best within range of temp and pH
Make reaction occur faster
NOT used up or changed in reaction; can be used over and over
Substrate (reactant) specific: lock and key
ENZYME-SUBSTRATE COMPLEX
Substrate (reactant)
enzyme
Active site
Products
enzyme
PAGE 24 <ENZYMES>
PAGE 25 <CELL THEORY>
1.
2.
3.

All living things are composed of cells
Cells are the basic unit of structure and
function in all living things
New cells are produced from pre-existing
cells
Contributing Scientists
 Robert Hooke- Named cells, cork
 Anton van Leeuwenhoek- microorganisms (pond water)
 Matthias Schleiden- botanist, plant cells
 Theodor Schwann- animal cells
 Rudolf Virchow- cell division
PAGES 26-27
<PROKARYOTE VS EUKARYOTE VENN DIAGRAM>
26
27
Prokaryotes
Eukaryotes
differences
differences
similarities
PAGES 26-27
<PROKARYOTE VS EUKARYOTE VENN DIAGRAM>
26
27
Prokaryotes
Eukaryotes
differences
Differences


All single
cellular
pili
similarities

Cell membrane

Cell wall

Contain DNA

Cytoplasm

Flagella

Reproduce

Respond to
environment

Ribosomes

Unicellular organisms

Centrioles

Contain nucleus

Golgi apparatus

Mitochondria



May become
specialized
Have complex
internal
structures
(membrane bound
organelles)
Some are singlecellular, some are
multicellular
PAGES 26-27
Words/phrases for Venn Diagram
All single-cellular
 Cell membrane
 Cell wall
 Centrioles
 Contain DNA
 Contain nucleus
 Cytoplasm
 Flagella
 Golgi apparatus
 Mitochondria
 May become specialized

Have complex internal
structures (membrane bound
organelles)
 Pili
 Reproduce
 Respond to environment
 Ribosomes
 Rough ER
 Smooth ER
 Some are single-cellular,
some are multicellular
 Unicellular organisms

PAGE 28 <ANIMAL CELL>
 Color
and label
animal cell
29
organelles:
28
Animal Cell










Nucleus
Nucleolus
Cell membrane
Rough ER
Smooth ER
Mitochondria
Golgi Apparatus
Centriole
Ribosome
Nuclear Envelope
Circle organelles not
found in plant cells
 Use a ruler for lines

 Color
and label:
Nucleus
 Nucleolus
28
 Cell membrane
 Rough ER
 Smooth ER
 Mitochondria
 Golgi Apparatus
 Ribosome
 Nuclear Envelope
 Cell wall
 Central vacuole
 Chloroplast

Circle organelles not found
in animal cells
 Use a ruler for lines

PAGE 29 <PLANT CELL>
29
Plant Cell
PAGE 30 <PROKARYOTIC CELL>
 Draw,
30
Prokaryotic Cell








color and label:
cell wall
cell membrane
pili
flagella
DNA (nucleoid region)
cytosol
ribosomes
Use a ruler for lines
PAGE 31
<CELL STRUCTURES AND FUNCTIONS>

1.
2.
3.
4.
5.
6.
7.
8.
9.
Match the Cell structures
10.
with their functions and copy 11.
into notebook
12.
cell membrane
13.
cell wall
14.
centrioles
15.
chloroplast
16.
chromatin
17.
cytoskeleton
18.
cytosol
19.
Golgi apparatus
20.
lysosome
mitochondria
nuclear envelope
nuclear pores
nucleolus
nucleus
organelles
ribosome
rough ER
smooth ER
vacuole
vesicles

Functions (match with correct structure)
• Control center of eukaryotic cell
• Term used to describe cell structures
• Site of detoxification & manufacture of lipids
• “Cell Gel”
• Converts energy stored in glucose to ATP
• Play a role in cell division of animal cells
• Maintains homeostasis in cell
• Provides shape and structure to cell; more extensive in animal cells
• Captures energy from the sun to produce glucose; site of photosynthesis
• “transport bubbles”; used to move biomolecules, etc.
• Structure that produces proteins in a cell
• Cell postmaster; packages & ships biomolecules
• Uses enzymes to disinfect, break down, and recycle
• Outermost boundary of plant, fungal, & bacterial cells
• Openings in membrane surrounding nucleus that allows for RNA to pass through
PAGE 31 <CELL STRUCTURES AND FUNCTIONS>
1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
13.
14.
15.
16.
17.
18.
19.
20.
cell membrane- Maintains homeostasis in cell
cell wall-Outermost boundary of plant, fungal, & bacterial cells
Centrioles- Play a role in cell division of animal cells
Chloroplast- Captures energy from the sun to produce glucose; site of
photosynthesis
Chromatin- DNA wrapped protein; genetic code
Cytoskeleton- Provides shape and structure to cell; more extensive in animal cells
Cytosol- “Cell Gel”
Golgi apparatus- Cell postmaster; packages & ships biomolecules
Lysosome- Uses enzymes to disinfect, break down, and recycle
Mitochondria- Converts energy stored in glucose to ATP
nuclear envelope- keeps nucleus separate from remainder of cell
nuclear pores-Openings in membrane surrounding nucleus that allows for RNA to
pass through
Nucleolus- produces ribsosomes
Nucleus-Control center of eukaryotic cell
Organelles-Term used to describe cell structures
Ribosome-Structure that produces proteins in a cell
rough ER- modifies and transports proteins; covered with ribosomes
smooth ER- Site of detoxification & manufacture of lipids
Vacuole- stores water and ions
Vesicles- “transport bubbles”; used to move biomolecules, etc.
PAGE 32 <VIRUSES>
RNA
capsid
DNA
capsid
RNA
capsid
proteins
tail
sheath
tail fiber
surface
proteins
Define in own words
 Virus:
 Capsid:
 Retrovirus:
 Lytic:
 Lysogenic:
envelope
PAGE 32 <VIRUSES>
RNA
capsid
DNA
capsid
RNA
capsid
proteins
tail
sheath
tail fiber
surface
proteins
envelope
Define in own words
 Virus: non-living particle made up of protein coat and genetic
material; cause illnesses
 Capsid: protein coat
 Retrovirus: virus with RNA as genetic material
 Lytic: Active infection where viruses replicate and burst cells
 Lysogenic: Inactive infection where viral DNA (genes) is
replicated along with host cell DNA; no symptoms
PAGE 33 <VIRUSES VS CELLS VENN DIAGRAM>
PAGE 33 <VIRUSES VS CELLS VENN DIAGRAM>
CELLS
VIRUSES
•1000 Xs smaller
•Carries out cellular
functions
•Cell Membrane
•Considered non-living
•Cytoplasm
•Does not carry out cellular
functions
•Evolve
•Genetic material
(DNA/RNA)
•Grow and develop
•Larger
•Make up living things
•Made up of genetic
material surrounded by
protein coat (capsid)
•Microscopic
•Obtain and Use Energy
•Reproduces independently
•Require host cell to
reproduce
•Respond to environment
•Some contain nucleus and
organelles
•(hint- 3 in common)
CELLS
-Carries out cellular
functions
-Cell Membrane
-Cytoplasm
-Grow and develop
-Larger
-Make up living
things
-Obtain and Use
Energy
-Reproduces
independently
-Respond to
environment
-Some contain
nucleus and
organelles
BOTH
-Evolve
-Genetic material
(DNA/RNA)
-Microscopic
VIRUSES
-1000 Xs smaller
-Considered nonliving
-Does not carry out
cellular functions
-Made up of genetic
material surrounded
by protein coat
(capsid)
-Require host cell to
reproduce
PAGE 34<VIRUS REPRODUCTION>
-TAPE IN LYTIC VS LYSOGENIC FOLDABLE
PAGE 34<VIRUS REPRODUCTION>
-descriptions for foldable; each # on diagram will have a
bullet
LYSOGENIC CYCLE
LYTIC CYCLE
•Assembly of new viruses
•Attachment of virus
•Cell division occurs as normal
•Formation of proteins to form new viruses
•Host cell DNA is digested
•Insertion of viral DNA into host cell
•Lysis of cell and release of new viruses
•Rare Occasions- Prophage leaves host
chromosome and enters lytic cycle
•Replication of Viral DNA
•Viral DNA integrated into host cell DNA
7- Lysis
of cell and
PAGE
34<VIRUS
REPRODUCTION>
release of new viruses
1- Attachment of virus
6-Assembly of
new viruses
LYTIC CYCLE
Active,
Symptomatic
5- Formation of proteins
to form new viruses
2- Insertion of viral
DNA into host cell
5- Rare OccasionsProphage leaves host
chromosome and
enters lytic cycle
LYSOGENIC
CYCLE
Inactive,
asymptomatic
4- Cell division
occurs as normal
4- Replication of
Viral DNA
3- Host cell DNA
is digested
3- Viral DNA integrated
into host cell DNA
PAGE 35 <CELL MEMBRANE>
Define:
Phospholipid bilayerSelective Permeability (Semi-Permeable)HomeostasisEquilibrium-
PAGE 35 <CELL MEMBRANE>
Cholesterol
Phospholipid bilayer- 2 layers of phospholipids where hydrophic tails
are on inside and hydrophilic heads are on outside
Selective Permeability (Semi-Permeable)- Only allows some substances
to enter and exit the cell
Homeostasis- Maintaining stable internal environment
Equilibrium- Concentrations are equal everywhere
PAGE 36 <TYPES OF MEMBRANE TRANSPORT>
-O2, CO2
-H2O (osmosis)
protein
Cell membrane(phospholipid
bilayer)
-Sugars
-High to low
concentration
(with gradient)
(energy)
protein
-Low to high
concentration
(against gradient)
PAGE 37 <OSMOSIS>
BEFORE
AFTER
Shrink,
Expand, or
Stays same?
Hypertonic,
Hypotonic,
or Isotonic?
CELL
CHANGE
TYPE OF SOLUTION
OUTSIDE CELL
PAGE 37 <OSMOSIS>
BEFORE
AFTER
Shrink,
Expand, or
Stays same?
Hypertonic,
Hypotonic,
or Isotonic?
CELL
CHANGE
TYPE OF SOLUTION
OUTSIDE CELL
Expand
Hypotonic
Stays same
Isotonic
Shrink
Hypertonic
PAGE 38-39 <MEMBRANE TRANSPORT
CONCEPT MAP>
Active transport
 Against
 Diffusion
 Endocytosis
 Equilibrium
 Exocytosis
 Facilitated diffusion
 High (2 times)
 Homeostasis
 Hypertonic
 Hypotonic
 Isotonic

Low (2 times)
 Osmosis
 Passive transport
 Phagocytosis
 Pinocytosis
 Protein pumps
 Selectively (Semi-)
 Shrink (Shrivel)
 Stay same
 Swell (Expand)
 With

PAGE 38-39 <MEMBRANE TRANSPORT
CONCEPT MAP>
PAGE 40 <CHEMICAL ENERGY> DRAW AND COLOR
PAGE 41 <OBTAINING ENERGY>

Autotroph
Definition in own words
 2 drawings/examples


Heterotroph
Definition in own words
 2 drawings/examples

PAGE 42 <PHOTOSYNTHESIS>
Location:
Reactants:
Products:
Organisms:
_______
captured
43 <CELL RESPIRATION >
# ATP produced
Glycolysis:
Kreb Cycle:
ETC:
_______
_______
_______
_______ released
_______
Equation:
Equation:
Location:
Reactants:
Products:
Organisms:
PAGE 42 <PHOTOSYNTHESIS>
Location: chloroplast
Reactants: 6CO2 + 6H2O +energy
Products: C6 H12 O6 + 6O2
Organisms: Autotrophs
Sunlight
energy
43 <CELL RESPIRATION >
# ATP produced
CO2
Glycolysis: 2
Krebs Cycle: 2
ETC: 32
TOTAL=36 ATP
H2O
C6 H12 O6
ATP for work
O2
Location: Mitochondria
Reactants: C6 H12 O6 + 6O2
Products: 6CO2 + 6H2O + energy
Organisms: Autotroph & heterotroph
Equation:
6CO2 + 6H2O +energy → C6 H12 O6 + 6O2
Equation:
C6 H12 O6 + 6O2 →6CO2 + 6H2O + energy
PAGE 42 <PHOTOSYNTHESIS>
Location: chloroplast
Reactants: 6CO2 + 6H2O +energy
Products: C6 H12 O6 + 6O2
Organisms: Autotrophs
Sunlight
energy
43 <CELL RESPIRATION >
# ATP produced
CO2
Glycolysis: 2
Krebs Cycle: 2
ETC: 32
TOTAL=36 ATP
H2O
thylakoid
matrix
cristae
Outer membrane
grana
stroma
C6 H12 O6
ATP for work
O2
Location: Mitochondria
Reactants: C6 H12 O6 + 6O2
Products: 6CO2 + 6H2O + energy
Organisms: Autotroph & heterotroph
Equation:
6CO2 + 6H2O +energy → C6 H12 O6 + 6O2
Equation:
C6 H12 O6 + 6O2 →6CO2 + 6H2O + energy
PAGE 44 <CHROMOSOMES> draw and color
CHROMOSOME
chromatid
chromatid
Centromere
PAGE 45 <CELL CYCLE> draw and color
PAGE 46-47 <MITOSIS>
INTERPHASE
(G1, S, G2)
PROPHASE
CYTOKINESIS
METAPHASE
TELOPHASE
ANAPHASE
PAGE 47 <MITOSIS>
INTERPHASE
(G1, S, G2)
PROPHASE
CYTOKINESIS
METAPHASE
TELOPHASE
ANAPHASE
PAGE 48 <DNA>
Color code and fill in blanks
DNA stands for: ___________________________________
Monomers are called: ______________________________
Each monomer contains: 1234 different Nitrogen bases: __________________________
________________________________________________
______ bonds with ______ and ______ bonds with ______
PAGE 48 <DNA>
Color code and fill in blanks
DNA stands for: deoxyribonucleic acid
Monomers are called: nucleotides
Each monomer contains: 1-sugar (deoxyribose)
2- phosphate
3-nitrogen base
4 different Nitrogen bases: adenine, thymine, guanine, cytosine
A bonds with T and C bonds with G
PAGE 49 <3 Types of RNA>
______
__ RNA
__ RNA
__ RNA
______
RNA stands for: ___________________________________
Monomers are called: ______________________________
Each monomer contains: 1234 different Nitrogen bases: __________________________
________________________________________________
______ bonds with ______ and ______ bonds with ______
PAGE 49 <3 Types of RNA>
codon
______
m
__ RNA
t RNA
__
r RNA
__
anticodon
______
RNA stands for: ribonucleic acid
Monomers are called: nucleotides
Each monomer contains: 1-sugar (ribose)
2- phosphate
3-nitrogen base
4 different Nitrogen bases: adenine, uracil, guanine, cytosine
A bonds with U and C bonds with G
PAGE 50 <Protein Synthesis>
Label the following structures:
•Cell Membrane
•amino acid
•nucleus
•polypeptide chain (protein)
•nuclear envelope
•codon
•nuclear pore
•anticodon
•tRNA
•ribosome
•mRNA
PAGE 50 <Protein Synthesis>
polypeptide
chain (protein)