A-level Chemistry independent research projects
Optical isomers:
Properties, uses, social impacts and controlled
production
Background:
Optical isomers are a sub-division of stereoisomers. The term ‘stereo’
is derived from the Greek for solid which was a word used to describe
three-dimensionality. The term ‘isomer’ is derived from the Greek
word meaning equal parts.
Thalidomide was an anti-nausea drug used in the 1960’s to alleviate the
symptoms of morning sickness in pregnant women. Its usage led to
some devastating consequences which are still affecting people’s lives
to this day. Despite this, Thalidomide is once again being used by
doctors, this time for positive effect.
Task:
Using this, or an example of your choice, research the properties and
production of a pair of optical isomers. Produce a five minute
presentation which will be delivered to the rest of the class, along
with a worksheet which will help students to understand what optical
isomers are.
Success criteria:
You should be able to define, identify and draw optical isomers and
discuss similarities and differences in their chemical and physical
properties. You should be able to discuss the considerations
manufacturers must take when producing an optically active product.
Curriculum links:
 This project has curriculum links with Unit 4 Isomerism
 Key words include: stereoisomer, optical isomer, plane polarised
light, enantiomer, race mate, racemic, chiral centre, optical
enzyme/catalyst