Digestive System By: Isaías Quezada, Emely Rivera, Carlos Sandoval Per.5 Overview The digestive system consists of the Alimentary canal: 1.Mouth 2.Pharynx 3.Esophagus 4.Stomach 5.Small intestine 6.Anal canal Accessory structures: 1.Salivary glands 2.Liver 3.Gallbladder Structure of the Alimentary Canal’s Walls Its' walls consist of four distinct layers that are developed to different degrees from region to region. Certain regions are specialized for certain functions. These layers are: 1.Mucosa 2.Submucosa 3.Muscular Layer 4.Serosa Mucosa formed of surface epithelium, lamina propria(connective tissue), and a small amount of smooth muscle Function are protection, secretion, and absorption Submucosa Contains loose connective tissue, glands, blood vessels, lymphatic vessels, and nerves Function is to nourish surrounding tissues and carry away any absorbed materials Muscular Layer consists of two coats of smooth muscle tissue arranged in circular and longitudinal groups Provides movement of the tube and its contents Serosa outer covering of the tube and comprised of visceral peritoneum, which is formed of epithelium on the outside and connective tissue beneath Its function is both protection and lubrication Types of Movement There are two main motor functions of the alimentary canal; mixing & propelling Types of Movement: Mixing Occurs when smooth muscles in small segments of the tube contract rhythmically When the stomach is full, waves of muscular contractions move along its wall from one end to the other. The waves occur every twenty seconds and they mix foods with the digestive juices that the mucosa secretes Types of Movement: Propelling a wave-like motion called peristalsis occurs a ring of contraction appears in the wall of the tube, yet just ahead the muscular wall relaxes This action begins when food expands the tube Mouth First portion of alimentary canal Receives food Begins mechanical digestion Breaks food into smaller pieces Organ of sensory and speech Cheeks Lateral walls of mouth Consist of outer layers of skin Pads of subcutaneous fat Muscles that help with expressions and chewing Moist inner layers moist, stratified squamious epithelium Lips Mobile structures surrounding mouth Contain skeletal muscle Judges temperatures and texture of food Reddish color comes from amount of blood cells External borders mark boundaries between skin of face and mucous membrane that lines in alimentary canal Tongue Muscular organ rest on the bottom of the mouth Covered by mucous membrane Connected by midline to the floor by membranous fold, lingual frenulum Composed of skeletal muscle fibers that run in several directions Papillae Root held by hyoid bone Palate Roof of oral cavity Hard anterior , soft posterior Hard palate formed by palatine processes of maxillary soft palate forms a muscular arch Uvula Muscles here help with swallowing Palatine tonsils Pharyngeal tonsils. Teeth Hardest structures in body Not considered part of the skeletal system Develop in sockets in alveolar process of mandibular and maxillary bones Permanent teeth come at about six years old They break food into smaller particles, thus beginning the mechanical process Helps mix food with saliva Salivary Glands Secretes saliva minor glands are found on mucosa of the mouth Constantly secreting fluid to keep mouth moist There are 3 pairs of major glands, parotid, submandibular, sublingual Secretion Secretory cells within the glands, Serous, and Mucous cells Serous cells contain salivary amylase. Enzymes split starch and glycogen molecules, they then become disaccharides This begins chemical digestion Mucous cells secrete mucus Glands have parasympathetic and sympathetic nerves Pharynx Connects nasal and oral cavity with larynx and esophogus Nasopharynx o Located: superior to the soft palate o Communicates with the nasal cavity and provides a passageway for air during breathing Oropharynx o Located: posterior to the mouth o Passageway from the mouth for air moving to and from the Pharynx (continued) Laryngopharynx o Located: inferior to the oropharynx o Extends from the upper boarder of the….downward to the lower boarder of the cyroid cartilage of the larynx and is a passageway to the esophagus Esophagus Straight, collapsible tube that is about 25 cm. long Provides a passageway for food Cardiac Sphincter Remain contracted Close entrance to the stomach Prevents regurgitation Parts of the Stomach: Cardiac Region A small are near the esophageal opening, or cardia This is where the contents of the esophagus empty into the stomach Parts of the Stomach: Fundic Region Serves as a temporary storage area and sometimes fills with swallowed air This produces a gastric air bubble which may be used as a landmark on a radiograph of the abdomen Parts of the Stomach: Body Region The main portion of the stomach and located between the fundic and pyloric portions The main chamber for containing food Parts of the Stomach: Pyloric Region Funnel-shaped Shape narrows and becomes the pyloric canal as it approaches the small intestine At the end, the circular layer of fibers in its muscular wall thickens and forms the muscle Pyloric Sphincter, which acts as a valve that controls gastric emptying Gastric Secretions The stomach’s mucous membrane is studded with gastric pits, located at the ends of tubular gastric glands Their structure and composition of their secretion vary in different parts of the stomach All gastric glands generally contain 3 types of secretory cells Secretory Cells Mucous Cells: found in the necks of the glands near the openings and is responsible for lining the stomach from digestive juices Chief Cells: also known as peptic cells are a key component of gastric juices Parietal Cells: also known as oxyntic cells. When the chief cells secrete enzymes and parietal cells release a hydrochloric acid solution, they form the gastric juices Major Components of Gastric Juices Components Source Function Pepsinogen Chief Cells of the Gastric glands Inactive form of pepsin Pepsin Pepsinogen in the presence of hydrochloric acid Protein-splitting enzyme that digests all dietary protein Hydrochloric acid Pepsinogen in the presence of hydrochloric acid Protein-splitting enzyme that digests all dietary protein Mucus Goblet cells and mucous glands Provides viscous alkaline protective layer on the inside of the stomach wall Intrinsic factor Parietal cells of the gastric glands Aids in vitamin B12 absorption Phases of Gastric secretions Phase Action Cephalic phase Sight, taste, or thought of food triggers parasympathetic reflexes. Gastric juice is secreted in response Gastric phase Food in stomach chemically & mechanicaly stimulates release of gastrin, stimulating secretion of gastric juice; reflex response also stimulate gastric juice secretion Intestinal phase As food enters small intestine, it stimulates intestinal cells to release intestinal gastrin, promoting the secretion of gastric juice from the stomach wall. Pancreas Endocrine Gland/exocrine function Secretes pancreatic juices Pancreas (structure) Located posterior to parietal peritoneum Pancreatic acinar cells: produce pancreatic cells Aclai: clusters around tiny tubes which release their secretions Small tubes connect to pancreatic duct Pancreatic duct connects with duodenum Stomach A J-shaped pouch like organ in the abdominal cavity It receives food from the esophagus, mixes it with gastric juices, initiates the digestion of proteins, carries on limited absorption, and transports food into small intestine Divided into four sections; 1.Cardiac region 2.Fundic section region 3.Body regions 4.Pyloric regions Liver • • • • • • • Largest gland in the body Weights 3.2 – 3.7 pounds Detoxifies blood Creates bile for stomach Stores vitamins, iron, simple sugar glucose Converts ammonia to urea Very Likely to get disease due to the mass of functions it carries out Gallbladder • • • • Pear shaped Stores conventrate bile Stores any bile that is not used Cholecystokinin causes the release of bile to small intestine • Cholestoral, bile salts, can create Gallstones Regulation of Bile Release Small Intestine A tubular organ that extends from the pyloric sphincter to the beginning of the large intestine Recieves secretions from the pancreas and liver Completes digestion of the nutrients in chym Macromolecules Carbohydrates Begins in the mouth Parctially digested carbs travel to esophagus and then the stomach Move to the small intestine where they are broken down by enzymes from the pancreas Then absorbed into the blood stream Fiber passes through undigested Lipids Some digested in mouth and stomach Mainly in the small intestine Bile produced in liver is sent to gallbladder Fatty acids combine with cholesterol and bile Transported to veins of chest and the blood carries fat to be stored in adipose tissue Macromolecules (cont) Proteins Digested into amino acids Begins in stomach with gastric juice Potent enzymes from pancreas Continues to the small intestine Amino acids absorbd into the blood Duodenum Shortest and most fixed portion of the small intestine C-shaped Recieves the partly digested food Jejunum Greater diameter Thicker wall More vascular More active Support absorption of carbohydrates and protiens Ileum More lymph nodules Higher bacterial population Absorb chyme Large Intestine 1.5 meters long Consists of cecum, colon, rectum, and anal canal Begins in iliac region of pelvis Joined together with small intestine Continues across and down the abdominal cavity, and ends at the anus Takes 16 hours to digest Transports waste and re-absorption of water before it gets secreted. Absorbs water and vitamins Reduces Acidity Cecum Tube like structure in lower abdominal cavity Receives undigested food from small intestine Absorbs fluids and salts that remain after intestinal digestion and absorption Mixes the contents with mucus Has a thick layer of mucous membrane Layer of muscle that makes churning and rubbing movements Colon Removes water, salt, and nutrients that form stool Muscles squeeze the contents through the intestine Bacteria is found along the walls of the colon 4 parts, descending, ascending, transverse, and sigmoid Supported by peritoneum Rectum 10 to 12 cm Dilates towards the anus Stores feces Stretch receptors in walls tell when the body needs to defecate When the rectum storage is full, the pressure pushes the feces to the anus Body temperature can checked from rectum area Anal Canal 3-5 cm Lubricates feces as it comes from rectum Has muscular sphincter system that closes lumen External anal sphincter surrounds anal canal and acts like a clamp. Similar to the puborectalis muscles that covers rectum from behind. Both of which are voluntarily controlled Internal anal sphincter relaxes so blood in anal cushions drain, which allows feces to go through Hormones Hormone Function Hormone Function Gastrin Produce acid to dissolve food Ghrelin Stimulates appetite Paptide YY Inhibits appetite Leptin Tells the body it is full Intestinal gastrin Increase activity of gastric glands Inner/Somatostatin Inhibits secretion of acid Cholecystokinin Decrease activity of gastric glands; stimulates pancrease; stimulates gallbaldder Secretin Stimulates pacreas to secrete fluid