مدرسة المشرق الدولية Mashrek International School NAME: CLASS: MYP 5 A/B/C/D TOPIC: RESPIRATION & RESPIRATORY SYSTEM DATE: / / 2011 STUDY HANDOUT BREATHING & RESPIRATION 1 UNIT QUESTION: Why do living organisms respire? SIGNIFICANT CONCEPTS Before starting with this chapter you need to revise respiration chapter and be able to answer the following: Distinguish between aerobic and anaerobic respiration Name the uses of energy in humans Differentiate between respiration and breathing Understand the production and effects of lactic acid in human muscles during vigorous exercise After completing this chapter, you will be able to: Understand the mechanism of gaseous exchange in humans To know the properties of an ideal gas exchange surface Investigate the effect of exercise on rate of depth of breathing Relate the features of alveoli to its gaseous exchange function To list some of the respiratory problems related to smoking Tobacco AREA OF INTERACTION: HEALTH AND SOCIAL EDUCATION In this unit you will gain insight into the respiration and respiratory system within the human body. You will also be encouraged to develop a better understanding of the possible medical problems associated with pollution and smoking SUMMATIVE TASKS: - Lab investigation: Criteria D, E & F Investigate the factors that affect the respiration in yeast - Unit test: Criteria C End unit test Summative tasks will be given separately from this booklet DURATION: 2 weeks 2 UNIT MAP 3 RESPIRATION: Energy is needed by all living cells to be used in a wide range of processes such as active transport, cell division and protein synthesis. ATP is an energy molecule that stores energy and used by cells. Every cell produces its own ATP by CELLULAR RESPIRATION. Define cellular respiration. ……………………………………………………………………………………. …………………………………………………………………………………………………………………. Cellular respiration has two types CELLULAR RESPIRATION Aerobic Respiration - Oxygen needs: ………………… Location in the cell: ……………………………. - Amount of energy:……………………………… - Word equation: - Symbol equation: ………………………………………………………………………………………………………….. ………………………………………………………………………………………………………….. Anaerobic Respiration - Oxygen needs: ………………… Location in the cell:…………………… - Amount of energy:……………………………… Types Lactic acid Fermentation (in muscle cells under stress) Alcohol Fermentation (in Yeast ) - Word equation: - Word equation: - Symbol equation: - Symbol equation: 4 LACTIC ACID FERMENTATION (IN MUSCLE CELLS) Work must be done to contract the muscle. The energy for this comes from aerobic respiration. The oxygen comes from the air. It is taken in at the lungs and carried around the body in the blood, pumped by the heart. Glucose comes from food digested and also carried by the blood. Muscles have blood capillaries that supply glucose and oxygen for respiration, and to carry away carbon dioxide and heat that is produced during respiration. When the muscles work very hard they use up a lot of energy. The heart and the lungs, cannot supply enough oxygen to provide this energy by aerobic respiration. In this case muscles can release energy by anaerobic respiration. Note: One measure of a person's fitness is how quickly their breathing and pulse return to normal after exercise. This is because in a fit person aerobic respiration is more efficient, so they build up less of an oxygen debt while exercising, and need less extra oxygen to breakdown any lactic acid in their muscles resulting from anaerobic respiration. TEST YOURSELF: Q. Fill in the table below to compare between aerobic and anaerobic respiration Aerobic respiration Anaerobic respiration Is oxygen needed How much energy released What are waste products Animal cell: In yeast: Where does it occur in the cell 5 GASEOUS EXCHANGE IN ANIMALS Q1. Explain why mammals need a breathing system and other unicellular organisms don’t, although they both respire? ……………………………………………………………………………………………………………….. ………………………………………………………………………………………………………………... ………………………………………………………………………………………………………………… Q2. Distinguish between breathing (ventilation), gas exchange and respiration Ventilation:………………………………………………………………………………………………………… ……………………………………………………………………………………………………………………. Gas Exchange:…………………………………………………………………………………………………….. ……………………………………………………………………………………………………………………. Respiration:………………………………………………………………………………………………………... ………………………………………………………………………………………………………………… FUNCTION OF THE RESPIRATORY SYSTEM 1. Enriching the blood with oxygen and getting rid of the carbon dioxide. 2. Excreting the excess water from the body as water vapor. 3. Smelling odors 6 STRUCTURE OF THE RESPIRATORY SYSTEM : Figure 1: Respiratory system 1. Nose The air can enter the body through either the nose or the mouth. The nose and the mouth are separated by the PALATE . Q3. List the advantages of breathing in from the nose? 1. …………………………………………………………………………………………………………………. 2. ………………………………………………………………………………………………………………….. 3. ………………………………………………………………………………………………………………….. 2. Larynx Larynx is the voice box of the body that contains the vocal cords for production of sound when air passes over them. 7 3. Trachea The trachea goes down through the neck and into the thorax (upper part of the body from the neck down to the bottom of the ribs and diaphragm) The air enters the trachea (windpipe) that strengthened by rings of cartilage to prevent it from collapsing; also it is all covered with ciliated cells and goblet cells. Q4. Describe the function of cilia and mucus that lines the respiratory tract? ……………………………………………………………………………………………………………….. ……………………………………………………………………………………………………………….. ……………………………………………………………………………………………………………….. 4. Lungs : Each lung lies in the pleural cavity which is lined by elastic membrane called pleural membrane. The thin layer of lubricating fluid between the membrane decrease friction with the chest walls while the lungs expand and contract during breathing. 5. Bronchi ( singular bronchus) In the thorax trachea divides into two bronchi, one goes to each lung and the branches out into many smaller tubes called Bronchioles Both bronchi and bronchioles supported by rings of cartilage, and covered with ciliated cells and mucus to filter the air Figure 2: Inside the Lungs 8 6. Alveoli (singular : Alveolus) At the end of each bronchiole are tiny sacs called alveoli. This is where gas exchange takes place. Figure 3: Alveoli Q5. State and explain the main characteristics that make the alveoli suitable for rapid gas exchange? 1. ……………………………………………………………………………………………………………….. ……………………………………………………………………………………………………………….. 2. ……………………………………………………………………………………………………………….. ……………………………………………………………………………………………………………….. 3. ……………………………………………………………………………………………………………….. ……………………………………………………………………………………………………………….. 4……………………………………………………………………………………………………………….. . ……………………………………………………………………………………………………………….. 9 How does oxygen diffuse from alveoli to blood? As air full of oxygen enters fills the alveolus the concentration gradient of oxygen is higher than in the blood. The O2 will dissolve in the moisture lining the alveolar walls then diffuse into the RBC and combines with the hemoglobin to form an unstable compound called oxy-hemoglobin, to be carried along to the heart through pulmonary vein. Hemoglobin + oxygen oxy-hemoglobin Note: This is a reversible reaction Figure 4: Gas Exchange Q6. Describe how does CO2 diffuse out of the blood into alveolus? ……………………………………………………………………………………………………………….. ……………………………………………………………………………………………………………….. ……………………………………………………………………………………………………………….. ……………………………………………………………………………………………………………….. MECHANISM OF VENTILATION Ventilation involves two very important muscles: 1. The diaphragm which is a large sheet of elastic tissue which stretches across your body, underneath the lungs and heart. 2. The intercostal muscles made up of enternal and external intercostal muscles Figure 5: The process of Ventilation 10 A. INHALATION or (INSPIRATION): The process by which air enters the lungs: Q6. Describe and explain process of inhalation? ……………………………………………………………………………………………………………….. ……………………………………………………………………………………………………………….. ……………………………………………………………………………………………………………….. ……………………………………………………………………………………………………………….. ……………………………………………………………………………………………………………….. B. EXHALATION or (EXPIRATION): The process by which air leaves the lungs. The steps are: Q7. Describe and explain process of exhalation? ……………………………………………………………………………………………………………….. ……………………………………………………………………………………………………………….. ……………………………………………………………………………………………………………….. ……………………………………………………………………………………………………………….. ……………………………………………………………………………………………………………….. Comparison of inspired and expired air As a result of gas exchange, the proportion of oxygen and carbon dioxide in the inhaled/exhaled air changes with the air we breathe in containing a higher percentage of oxygen and a lower percentage of carbon dioxide than the air we breathe out. (Nitrogen, the main component of air, remains unaffected by breathing and stays at the same percentage.) 11 BREATHING RATE AND LUNG CAPACITY The amount of air that enters and leaves the lungs is measured using a SPIROMETER. A person breathes in and out of a mouthpiece connected to a chamber. Inside the chamber a piston moves up and down, and its movements are measured electronically. The changes in volume during breathing are pointed on a graph called a SPIROGRAM shown below Q7. List the factors that affect lung volume (capacity) ……………………………………………………………………………………………………………….. ……………………………………………………………………………………………………………….. Q8. Define the following terms: - Tidal Volume: …………………………………………………………………………………… ………………………………………………………………………………………………………… - Vital Capacity: ……………………………………………………………………………………… ……………………………………………………………………………………………………………….. - Residual volume: ……………………………………………………………………………………… ……………………………………………………………………………………………………………….. Q9. Explain what stimulates the body to breath faster or slower? ……………………………………………………………………………………………………………….. ……………………………………………………………………………………………………………….. ……………………………………………………………………………………………………………….. 12 EFFECT OF SMOKING TOBACCO ON THE HEALTH OF THE RESPIRATORY SYSTEM When tobacco is smoked, it gives out certain chemicals that are harmful to the human body. These chemicals are the following: 1. Nicotine 2. Tar 3. Carbon monoxide Tobacco is a plant that is dried and rolled into cigarettes and smoked. The smoke given out from burning the cigarette can harm the lungs and respiratory passages for a number of reasons a. It is hot b. It has a drying effect c. It contains harmful chemicals like, Nicotine, Tar and Carbon monoxide and sulphur dioxide Nicotine is another chemical that is released when tobacco is smoked. Nicotine is a stimulant that makes the person more alert and active which affects the heart rate. Tar is a brownish chemical that is released when tobacco is smoked. Tar is very harmful to the body, as it - sticks to the teeth to cause their discoloration. The teeth become yellowish to brown. It also causes gum disease and plaque on the teeth. - damages the cilia that is found in the trachea, bronchi and bronchioles. When the cilia is damaged, the dust , the bacteria and the dirty mucus cannot be filtered and causes extra mucus made by goblet cells. These substances will remain in the lung causing infections mainly CHRONIC BRONCHITIS - will make the alveoli walls weak. Whenever the smoker coughs, the alveoli will burst. This is called EMPHYSEMA. Loosing alveoli, will make the surface area of gas exchange less. This will make patients breathless and exchausted. - Tar is the major cause of developing lung cancer and cancers of the bladder, and stomach Carbon monoxide is a gas that attaches itself to the hemoglobin of the RBC much easier than the oxygen. This means that when one smokes tobacco, less oxygen will reach the cells because carbon monoxide takes its place. When less O2 is reaching the cells, the person will feel tired, breathless , dizzy and weak. This is why smokers are tired when they do exercise. CO and nicotine will cause the blood of smokers to clot faster causing artery blockage. PASSIVE SMOKERS ( NON-SMOKERS) o People who do not smoke are called non-smokers. Non-smokers who live in an area where smoking is taking place are called PASSIVE SMOKERS because they are being exposed to the smoke of tobacco. o Non smokers are at risk of developing all the diseases that are caused by tobacco including lung cancer. For every 10 cigarettes that a smoker smokes, a passive smoker will be smoking one cigarette. o Passive smokers usually complain of the following: headaches, watery eyes and runny nose. 13 TEST YOURSELF: Q1. Write true if the statement is true or false if the statement is false. ______ 1. All organisms on earth will die without a constant supply of oxygen. ______ 2. Energy released during the breakdown of cells is used to synthesize ATP. ______ 3. The energy released from the breakdown of a single molecule of glucose can be used to synthesize up to 38 molecules of ATP ______ 4. When glucose is broken down during cellular respiration, a product is light energy. ______ 5. In eukaryotic cells, glycolysis occurs in the mitochondrion. ______ 6. All ATP synthesis in a eukaryotic cell happens in the mitochondria. ______ 7. Carbon dioxide is a product of both cellular respiration and photosynthes _____ 8. Emphysema can result in the blood being low in hemoglobin. _____ 9. The greatest contributing factor to lung cancer is inhaling the tar in cigarette smoke. _____ 10. People who produce too much mucus in the bronchial tubes have a disease called emphysema. _____ 11. A lung disorder often associated with allergies is called asthma. _____ 12. The diaphragm is a muscle beneath the lungs. _____ 13. The mucus lining of the trachea moves foreign particles to the esophagus. _____ 14. When you inhale, your diaphragm relaxes 14 Exercises: Q2 15 Q3. draw a section of an alveolus and capillary of a lung. Annotate the diagram to describe the movement of oxygen when it enters the lungs Q4. Fill in the blanks with the correct answer. 1. During respiration glucose is broken down to release………………………… 2. Energy is released in our cells inside these structures ………………………… 3. The gas produced during respiration……………………… 4. These structures are found inside your thorax and are used for breathing………………… 5. This happens to air as it passes along our air passages……………………. 6. Small air sacs that make up our lungs……………………… 7. Write down the pathway along which air passes from the larynx to the alveoli. ……………………………………………………………………………………………………. 8. Which structures protect the lungs? ………………………………………… 9. The muscles between the ribs…………………………………………. 10. A sheet of muscle separating the thorax from the rest of the body………………………………… 11. What happens to gases in the alveolus? …………………………………………… 16 12. Respiration without oxygen ……………………………………….. 13. A type of anaerobic respiration in yeast that makes alcohol…………………………………….. 14. During vigorous exercise, our muscles make this substance because they can’t get enough oxygen………….. 15. The extra oxygen needed to break down lactic acid is known as ………………………. 16. The smallest tubes in the lungs are the ____________________________ . 17. The ____________________________ prevents food from entering the larynx. 18. The pharynx is a passageway for ________________________ and ________________________ . 19. The alveoli are surrounded by ____________________________ . 20. Air entering your body is first moistened and warmed in the ___________________________ . 21. The trachea is kept open by rings made of ____________________________ . 17