CHAPTER 56: CARE OF THE PATIENT WITH HIV/AIDS Acute Interventions to Outlook For The Future Acute Interventions Acute Interventions Early intervention after detection of an HIV infection can promote health and limit or delay disability Assessment is of primary importance because the course of HIV is extremely variable Nursing interventions will be based on and tailored to any patient needs noted during assessment Nursing assessment of HIV disease should focus on the early detection of constitutional symptoms, opportunistic diseases, and psychosocial problems Box 56-6: Conducting a Risk Assessment Pg 2043 Conducting a Risk Assessment Risk assessment specific to HIV and sexually transmitted diseases (STDs), as well as blood borne diseases, is crucial in health care delivery today. Risk assessment should be done on a regular basis with all patients and performed with the evaluation of any new patient. Sexual and drug use risks should be determined along with other risks during routine history taking. Key Questions To Ask Any “yes” responses require further assessment and evaluation: Have you ever had a blood transfusion? Have you ever received any other kind of blood product? Before 1985? Do you now or have you ever shared injection equipment? Are you now or have you ever been sexually active? Key Points to Consider Begin by assuring confidentiality and telling the patient why asking these questions is important: “I am going to ask some personal questions. I ask all my patients these questions so I can provide better care. All of your responses will be kept confidential. Is it OK to proceed?” Key Points to Consider (cont) Ask direct questions about specific behaviors: “When was the last time you….?” “How often do you….?” “Have you ever exchanged sex for money or drugs?” Key Points to Consider (cont) Exploratory questions may help (especially with adolescents and young adults): “Do your friends use condoms?” “What happens at parties?” “How easy is it to get drugs?” Key Points To Consider (cont) Honest responses may be more forthcoming if the behaviors are normalized: “Some of my patients who use drugs inject them. Do you inject drugs or other substances? “Sometimes people have anal intercourse. Have you ever had anal intercourse?” Drug Use Assessment It is important to be nonjudgmental and nonmoralistic: Injection drug use is illegal in the U.S. and many patients are afraid to be honest unless trust is established Drug Use Assessment (cont) Start with less threatening questions: “What over-the-counter (OTC) or prescription medications are you taking?” “How often do you use alcohol? Tobacco?” “Have you ever used drugs from a nonmedical source?” “Have you ever injected any kind of drug?” Drug Use Assessment (cont) Do not assume anything: Drug use occurs in all socioeconomic strata. Do not forget that people inject substances such as insulin, steroids, and vitamins. Any sharing, even one time, can result in HIV exposure Drug Use Assessment (cont) Look for other clue in the history and physical exam: Antisocial behavior, recurrent criminal arrests, needle tracks Drug Use Assessment (cont) If there is a positive history of drug injection use, get more information: “Do/Did you share needles/other equipment?” “Is/Was the equipment you use(d) clean? How did you know it was clean?” “What drugs did you inject?” Sexual Risk Assessment Direct and nonjudgmental questions work best: “Do you have sex with men, women, or both?” “Do you have oral sex? Vaginal sex? Anal sex?” “What do you know about the sexual activities of your partners?” “What do you do to protect yourself during sex? “Do you use condoms? How often?” “Have you ever had sex with someone you didn’t know or just met?” Sexual Risk Assessment (cont) Ask for an explanation of sexual practices: “When you say you had sex, what exactly do you mean?” “I don’t know what you mean; could you explain….?” Sexual Risk Assessment (cont) Do not assume anything: Marriage does not always mean an individual is monogamous or heterosexual People who identify as homosexual may also have heterosexual sex Sexual Risk Assessment (cont) Use specific terms: Use “men who have sex with men” or “women who have sex with women” instead of gay. Some men do not consider themselves “gay” if they practice anal insertive intercourse, but their receptive partners are considered to be gay (can be culturally related). Clinical Risk Assessment Assess the patient for constitutional signs, history of chronic infection and HIV, and associated problems: Headaches; diarrhea; fatigue; shingles; history of STD, hepatitis, or TB; fever, chills, night sweats; skin lesions; weight loss; oral thrush; generalized lymphadenopathy Acute Interventions continuation Acute Interventions HIV disease progression may be delayed by promoting a healthy immune system Useful interventions for the HIV infected patient include the following: Nutritional changes that maintain lean body mass, increase weight, and ensure appropriate levels of vitamins and micronutrients; Elimination of smoking and drug use; Elimination or moderation of alcohol intake; Regular exercise; Stress reduction; Avoidance of exposure to new infectious agents; Mental health counseling; Involvement in support groups; Safer sexual practices Acute Interventions (cont) Nurse needs to help patients gain control of the situation and their emotions Facilitating empowerment is particularly important, because the individual with an HIV infection often experience loss, including an overwhelming feeling of loss of control Empowerment is facilitated through education and honest discussions about the patient’s health status Acute Interventions (cont) Patient should be taught to recognize clinical manifestations that may indicate progression of the disease This will ensure that prompt medical care is initiated Early manifestations that need to be reported: Unexplained weight loss, night sweats, diarrhea, persistent fever, swollen lymph nodes, oral hairy leukoplakia (OHL), oral candidiasis (thrush), persistent vaginal yeast infections Acute Interventions (cont) Patients should also report: Unusual headaches, changes in vision, nausea and vomiting, numbness and tingling in the extremities Patient should be given as much information as needed to make health care decisions Decisions will dictate the appropriate medical and nursing interventions Acute Interventions (cont) Nursing interventions become more complicated as the patient’s immune system deteriorates and new problems arise to compound existing difficulties Nursing focus should be on quality-of-life issues and symptom management, rather than on issues regarding a cure Acute Interventions (cont) When opportunistic diseases develop, symptomatic nursing interventions, education, and emotional support are necessary Example: acute case of PCP Interventions include monitoring the respiratory status, administering medications and oxygen, positioning the patient to facilitate breathing, managing anxiety, promoting nutritional support, and helping the patient conserve energy to decrease oxygen demand Because the potential for death is associated with advanced HIV disease, emotional support for the patient, caregiver, or significant other is particularly important Nursing Care Plan Box Pg 2044 to 2045 Nursing Diagnosis #1 Risk for caregiver role strain, r/t advancing disease in care receiver, lack of caregiver Patient Goals/Expected Outcomes: Caregiver will use available community and personal resources Caregiver will have the ability to complete necessary care giving tasks Effective support for caregiver Nursing Diagnosis #1 (cont) Nursing Intervention: Assess needs and capabilities of patient and caregiver Assess factors that contribute to caregiver strain (unrealistic expectations, poor insight, inability to use resources, unsatisfactory relationship with care receiver, insufficient financial and psychosocial resources) Develop supportive and trusting relationship with caregiver Nursing Diagnosis #1 (cont) Nursing Interventions (cont): Enlist help of other family members or friends to assist Teach caregiver to perform care activities in a safe, efficient, and energy-conserving manner Teach stress-reduction techniques Encourage caregiver to attend to own personal and health needs Nursing Diagnosis #1 Evaluation: The caregiver: Provides safe, supportive care to the HIV-infected patient Acknowledges need for personal support and accesses resources in family and community Shares frustrations about difficulty of care for significant other Receives assistance from family members and/or professional caregivers Nursing Diagnosis #2 Imbalanced nutrition: less than body requirements, r/t chronic infections and/or malabsorption, nausea/vomiting/diarrhea, fatigue, or side effects of medications as e/b 10% or greater loss of ideal body mass Patient Goals/Expected Outcomes: Patient’s weight will remain stable Patient’s nutritional intake will exceed metabolic needs Patient will regain lost weight Nursing Diagnosis #2 (cont) Nursing Intervention: Assist with diagnosis of underlying opportunistic infections Assess patient’s knowledge of optimal nutritional intake Increase protein, calorie, and fat intake Offer nutritional supplements (Carnation Instant Breakfast, Boost, Sustacal, etc.) Nursing Diagnosis #2 (cont) Nursing Intervention (cont): Schedule procedures that are painful, stressful, or nauseating so they do not interfere with mealtimes Eat several small meals throughout day as opposed to three larger meals Provide referrals to dietitians, social workers, and case managers Weigh patient daily Nursing Diagnosis #2 (cont) Evaluation: Weight will remain stable or increase Patient reports increased energy level Patient able to complete ADLs Patient experiences increase in lean muscle mass Acute Interventions continuation Acute Interventions Nursing interventions for diarrhea, which is a long-term problem for HIV-infected people include: Recommending dietary interventions Encouraging adequate fluid intake to prevent dehydration Instructing the patient about skin care Managing excoriation around the perianal area In some cases, nurse must administer antidiarrheals to help control and prevent further complications Recommend use of incontinence products to prevent soiling of the clothes and bed linens Table 56-11: Nutritional Management for HIV Infection Pg 2045 Dietary Recommendation Diarrhea Lactose-free, low-fat, low-fiber, and high-potassium foods Constipation High-fiber Nausea and Vomiting Low-fat foods foods Candidiasis Soft or pureed foods Dietary Recommendation (cont) Fever High-calorie, Altered Taste Diet as tolerated Anemia High-iron high-protein foods foods Fatigue High-calorie foods Intervention Diarrhea Avoid dairy products, red meat, margarine, butter, eggs, dried beans, peas, raw fruits and vegetables. Cooked or canned fruits and vegetables will provide needed vitamins. Eat potassium-rich foods such as bananas and apricot nectar. Discontinue foods, nutritional supplements, and medications that may make diarrhea worse (Ensure, antacids, stool softeners). Avoid gas-producing foods. Serve warm, not hot foods. Plan small, frequent meals. Drink plenty of fluids between meals. Intervention (cont) Constipation Eat fruits and vegetables (beans, peas), cereal, and whole wheat breads. Gradually increase fiber. Drink plenty of fluids. Exercise. Nausea and Vomiting Avoid dairy products and red meat. Plan small, frequent meals. Prepare nonodorous foods. Eat dry, salty foods. Serve food cold or at room temperature. Drink liquids between meals. Avoid gas-producing, greasy, spicy foods. Eat slowly in a relaxed atmosphere. Rest after meals with head elevated. Take antiemetics 30 minutes before meals. Intervention (cont) Candidiasis Serve moist foods. Drink plenty of fluids. Avoid acidic and spicy foods. Use straw and tilt head back and forth when drinking. To decrease discomfort, eat soft foods, such as puddings and yogurt. Fever Use nutritional supplements. Increase fluid intake. Intervention (cont) Altered Taste Try herbs and spices. Marinate meat, poultry, and fish. Serve food cold or at room temperature. Drink plenty of fluids. Add salt or sugar. Introduce alternative protein sources. Anemia Eat organ meats and raisins. Drink orange juice when taking iron supplements to facilitate absorption. Intervention (cont) Fatigue Cook in large quantities and freeze in meal-size packets. Use microwave and convenience foods. Use easy-to-fix snack foods. Use social support system to assist with meal planning and preparation. Access inhome homemaker services. Access community Meals on Wheels programs. Acute Intervention Wasting and Lipodystrophy Syndromes Wasting and Lipodystrophy Syndromes AIDS wasting has been a common clinical manifestation of HIV disease since early in the epidemic Wasting is due to disturbances in metabolism, which interferes with the effective use of nutrients, resulting in the loss of lean (muscle) body mass Wasting is characterized by depletion of lean body mass, without reduction of body fat This loss of lean body mass is a primary cause of functional decline in wasting Wasting and Lipodystrophy Syndromes (cont) Loss of lean body mass increases the risk for opportunistic infections, reduces quality of life, and reduces survival Causes of Wasting Most likely multifactorial Food intake may be inadequate because of mechanical difficulties Loss of appetite Psychological factors such as depression and anxiety Decreased absorption in intestines due to infections and a damaged mucosal barrier Some patients just stops eating to decrease the number of bowel movements per day Wasting and Lipodystrophy Syndromes (cont) Wasting causes disturbances in self-concept and self image Useful interventions for these disturbances Creating an atmosphere of acceptance and reassurance Encouraging a focus on past accomplishments and personal strengths Facilitating the use of positive affirmation Decreased levels of testosterone have been reported in 35 to 50% of HIV-infected men Wasting and Lipodystrophy Syndromes (cont) Testosterone has two distinct biologic properties: Virilizing activity (androgenic effect) Protein building (anabolic effect) A deficiency of testosterone may cause a loss of body cell mass, contributing to HIV wasting Women Due to testosterone being an anabolic hormone Lose a significant amount of body fat, but body cell mass is not significantly decreased Men Tend to lose a significant amount of lean body mass (skinny arms and legs) with the preservation of fat Wasting and Lipodystrophy Syndromes (cont) With the advances in HIV treatment and opportunistic infection prophylaxis, serious malnutrition is less evident However, nutrition does not return to normal after antiHIV treatment begins, and a syndrome of increased truncal obesity (abdomen), and metabolic abnormalities are developing Wasting and Lipodystrophy Syndromes (cont) Characteristic alterations in body composition of both men and women include: Development of truncal (visceral, abdominal) obesity Subcutaneous fat loss on the extremities and face Also called lipoatrophy Hyperlipidemia Insulin resistance Wasting and Lipodystrophy Syndromes (cont) 3 hypotheses to explain the mentioned changes: Changes are a side effect of either protease inhibitors or nucleoside reverse transcriptase inhibitors (AZT, d4T) Changes may represent an altered stress response, with mild chronic hypercortisolism in some patients Changes are part of long-term HIV disease and have only been noticed in recent years because of increased survival time Wasting and Lipodystrophy Syndromes (cont) The management of wasting and lipodystrophy is difficult Requires multiple interventions Nurse can assist by assessing for and documenting the presence of diminished appetite and weight Nursing interventions include: Encouraging nutritional supplementation; increasing protein intake; providing enteral supplements (through nasogastric or gastric tubes if necessary); and, assisting with total parenteral nutrition (TPN) Wasting and Lipodystrophy Syndromes (cont) May use appetite stimulants such as Megestrol (Megace) or Dronabinol (Marinol) These medications tend to increase body fat and not lean muscle mass unfortunately Testosterone (anabolic steroid) can be administer PO, IM, or transdermally to increase lean body mass and weight Effect of testosterone can be enhanced by the addition of a low-weight resistance-training program (weightlifting) because it maintains muscle tone and improves appetite Wasting and Lipodystrophy Syndromes (cont) Nutritional counseling is vital to ensure that individuals with HIV disease maintain a well balanced diet and include supplements if necessary Teaching about food safety is of paramount concern because enteric infections (cryptosporidiosis, microsporidiosis, and amebas) in HIV diseases are often not treatable or are relapsing In some cases, enteral and parenteral feeding becomes necessary Wasting and Lipodystrophy Syndromes (cont) Management of elevated triglycerides and lipids (cholesterol) is becoming common in HIV disease These elevations can lead to: Cardiac and vascular diseases Some cases, diabetes Lipid-lowering agents such as the statins may be effective in treating this complication A program of diet control, exercise, and medications can safely lower lipids and reduce the chances of a cardiovascular event occurring Wasting and Lipodystrophy Syndromes (cont) Insulin resistance and/or diabetes sometimes responds to oral hypoglycemic agents Some cases, anti-HIV therapy needs to be changed to a protease-sparing combination Managing diet, stopping smoking, weight loss, and exercise can help control the elevated blood sugars that can occur with the use of anti-HIV medication Wasting and Lipodystrophy Syndromes (cont) Metabolic needs of the HIV-infected individual increase by as much as 40% Results in the need for a higher energy expenditure than is provided by the number of calories taken in by the patient Malnutrition, weight loss, and generalized wasting are common problems in patients with HIV disease Estimated that as many as 70 to 90% of patients with HIV disease will experience wasting Wasting and Lipodystrophy Syndromes (cont) When a patient’s weight is reduced to 60% of his or her ideal body weight, death can occur, regardless of the underlying condition Malnutrition may influence morbidity and mortality in several ways Malnutrition contributes to wasting, and wasting hastens the negative immune consequences of HIV infection. HIV wasting contributes to slower recovery from infection, impaired wound healing, increased risk of secondary infection and decreased cardiac and respiratory function, and can lead to death Although typically seen in later stages HIV disease, malnutrition and wasting can occur in the early stages of HIV infection Acute Intervention Neurological Complications Neurological Complications: AIDS Dementia HIV-associated cognitive motor complex (previously known as AIDS dementia) is the term preferred by the WHO and the American Academy of Neurology (AAN) to describe a common CNS complication of HIV disease Frequency: Being anywhere between 20 and 33% of all adults and up to 50% of children with end-stage disease Neurological Complications: AIDS Dementia (cont) This condition is a complex combination of signs and symptoms: Dementia; impaired motor function; and, at times, characteristic behavioral changes that resemble an injury similar to a stroke or head trauma Generally does not cause alterations in the level of consciousness or psychiatric disturbances Usually described as a triad of cognitive, motor, and behavioral dysfunction that slowly progresses over a period of weeks to months Neurological Complications: AIDS Dementia (cont) Cognitive changes: Primarily involve a mental slowing and inattention. Patients typically lose their train of thought and complain of a slowness of thinking. Motor dysfunction: Develops after those of cognitive impairment. Includes poor balance and coordination (falling and tripping, dropping things); slower hand activities (writing, eating); and ultimately, leg weakness that can limit ambulation Neurological Complications: AIDS Dementia (cont) Diagnosis of this type of dementia can be made by conducting a simple physical examination, neurological testing, MRI/CT exams, and CSF analysis Nursing interventions for the treatment of neurocognitive dysfunction: Administration of anti-HIV medications and psychotropic medications (cautiously); supervise patient (this includes a home safety assessment); ensure that orientation cues such as clocks and calendars are present, hallways and living areas are brightly lit, walkways are clear of electrical cords or throw rugs, and potentially dangerous objects (knives, poisons) are safely stored away Neurological Complications: AIDS Dementia (cont) Caring for patients with dementia is a collaborative effort between health care provider and family It is advisable to seek advise from a social worker, home health care department, and a psychologist in developing a plan to care for an impaired individual AIDS-dementia complex (ADC), caused by HIV infection in the brain, is a common neurological disorder associated with HIV Neurological Complications: AIDS Dementia (cont) Dementia symptoms are sometimes reversible if a treatable cause can be diagnosed Treatable causes include: Dehydration Depression Medication toxicity or side effects Clinical manifestations Cognitive, behavioral, and motor abnormalities Neurological Complications: AIDS Dementia (cont) Symptoms: Decreased ability to concentrate, apathy, depression, social withdrawal, personality changes, confusion, hallucinations, altered levels of consciousness, slowed response rates ADC can lead to coma Nursing interventions are focused on patient safety and caregiver support Neurological Complications: Peripheral Neuropathy Diseases that affect the peripheral nervous system They can affect sensory, motor, or autonomic nerves Cause of neuropathies can be related to HIV disease itself, or more frequently, the side effects of many antiHIV medications Symptoms: Numbness, localized tingling, hypesthesia (diminished sensitivity to stimulation) or anesthesia, loss of vibration and position sense (proprioception), and decreased or increased sensitivity to pain Neurological Complications: Peripheral Neuropathy (cont) Most cases, patient complains of numbness in the fingers, hands and feet, and pain on walking May also experience autonomic neuropathy Symptoms such as mild positional hypotension to cardiovascular collapse, as well as chronic diarrhea, are suggestive of autonomic neuropathy Neurological Complications: Management of OIs With the advent of effective antiretroviral therapy and better understanding of OI prophylaxis, the frequency of OIs has decreased dramatically OIs still occur in the severely immunocompromised patients Nurses must be familiar with the recognition, treatment, and prophylaxis of these diseases OIs typically seen in: Those who are not adherent to their antiretroviral therapy, not adherent to OI prophylactic regimens, or at the end stage of HIV and in those who do not consistently access the health care system Neurological Complications: Health Promotion Because patients with HIV disease are living longer, more productive lives, attention to the promotion of health and healthy behaviors is important Patients should be encouraged to: Eat well-balanced meals, stop or at least reduce the number of cigarettes smoked, get adequate sleep and rest periods, use stress-reduction modalities (biofeedback, referral for counseling), obtain dental care regularly, keep scheduled appointments with all health care providers, get all immunizations and keep them up to date, female patients should regularly receive gynecologic care, participation of the patient and significant others in treatment decision making and arrange for home care follow-up if indicated Neurological Complications: Health Promotion Considerations (p 2048) Patient infected with HIV Remind patients that a positive diagnosis is not an immediate “death sentence”. Patients are living increasingly longer after diagnosis because of medications, more specialized care, and decreased morbidity and mortality related to opportunistic diseases Stress the importance of health-promoting behaviors to reduce the risk of comorbidity Encourage patients to maintain good nutritional status by eating regular, well-balanced meals that are high in protein and calories. Increased protein is necessary for cell and tissue repair- especially in patients who may be hypermetabolic Neurological Complications: Health Promotion Considerations (cont) Encourage patients to limit their intake of alcoholic beverages and avoid the use of illicit or recreational drugs Encourage patients to maintain an adequate sleep schedule Encourage patients to use stress reduction practices such as biofeedback, massage, or progressive relaxation. Engage in relaxing or pleasurable activities Encourage patients to use safer sexual practices to avoid reinfection and exposure to other sexually transmitted diseases Neurological Complications: Health Promotion Considerations (cont) Encourage patients to establish an exercise regimen that includes aerobic activity as well as low-resistance weightlifting of possible Most important, support patients in setting short- and long-term goals and assist them in achieving those goals Prevention of HIV Infection HIV Testing and Counseling to Other Methods to Reduce Risk Prevention of HIV Infection HIV disease is preventable Prevention takes cooperation and efforts of public health care providers, medical providers, nurses in all specialties, families, communities, churches, and schools Education on prevention is the only truly effective “vaccine” available to curb the HIV pandemic Nurses have a responsibility to assess each patient’s risk for HIV infection and counsel those at risk about HIV testing and the behaviors that put them at risk, and about how to reduce or eliminate those risks Prevention of HIV Infection Today, every nurse is in an HIV nurse, implying that all nurses are responsible for teaching methods to reduce risk of transmission Nurse must be able to discuss the details of behaviors relating to sexual activity and drug use in a forthright, relaxed, and nonjudmental manner Nurse must be able to establish rapport before asking sensitive, explicit questions and one must be comfortable with the discussion of risk-reduction techniques Harm-reduction education is a fundamental element of HIV prevention methods Prevention of HIV Infection Harm reduction does not completely eliminate the risk of HIV transmission. Instead, it focuses on minimizing the personal and social harms and costs associated with these activities HIV Testing and Counseling This is an integral part in the prevention of HIV transmission Patients should not be pressured to be tested Test decision counseling is the process of assisting patients in making decisions about when, if, and how to be tested It is important that the nurse takes every opportunity to provide pretest counseling Aside from providing the testing information, the nurse must also explain and obtain an informed consent before actually drawing blood This involves explaining the purpose, possible uses, limitations, and meaning of the test results HIV Testing and Counseling Consent policies are established by state laws and vary from state to state The most common and acceptable policy is to obtain informed written consent before HIV antibody testing All states have some exceptions to informed consent, usually relating to critical or emergency situations However, these situations are rare and every effort should be made to obtain consent HIV Testing and Counseling When obtaining consent, explain the applicable limits of confidentiality in the office, clinic, or hospital setting where the patient is being tested Patient should be told who will have access to the test results, such as the health department or insurance company, and what will be done with that information Ex: contact tracing or partner notification HIV antibody testing may take place in a physician’s office or at a designated HIV counseling and testing sites HIV Testing and Counseling Nurses must be aware of the various options for HIV antibody testing in their state or community in order to advise patients appropriately HIV testing can be done in one of two ways: confidentially or anonymously Confidential testing: individuals are asked to provide identifying information, including a name, address, and often demographics such as sex, age, race, and occupation HIV Testing and Counseling Anonymous testing: individuals are not asked to provide identifying information. Records are kept through assigned numbers, and the patient must retain this number to obtain results In either form of testing, pretest and posttest counseling can be performed by the nurse Risk Assessment and Risk Reduction Nurse should encourage early detection of HIV infection Testing for HIV is important part of the public health response to HIV disease Risk assessment should be patient centered, a joint process between nurse and patient Patient should take “ownership” of the risk for HIV infection Patients need to be assessed for manifestations that would be indicative of risky behaviors, such as STDs Risk Assessment and Risk Reduction Basic Questions Have you ever had a transfusion or used clotting factors? Was it before 1985? Have you ever shared needles, syringes, or other injecting equipment with anyone? Have you ever had a sexual experience in which your penis, vagina, rectum, or mouth came into contact with another person’s penis, vagina, rectum, or mouth? Risk Assessment and Risk Reduction Positive response to any of the mentioned questions will require the nurse to investigate further with the patient Nurse should be prepared to refer patient to centers that provide testing and counseling services Barriers to Prevention There are numerous barriers to HIV prevention, not the least of which is a denial of risk, an attitude that “it won’t happen to me” Fear, misunderstanding, and the potential for social stigma are significant barriers Cultural and community attitudes, values, and norms can affect the success of prevention efforts Prevention of HIV transmission requires a commitment to change behaviors that put one at risk Education to alter behaviors is a long-term process Risk Assessment and Risk Reduction Nurses need to take every opportunity to educate their patients on how to avoid or reduce the risk for HIV infection Collective efforts will have the greatest effect Fear of alienation and discrimination are significant additional barriers to prevention Reducing Risks Related to Occupational Exposure Risk of acquiring HIV through occupational exposure is quite rare CDC and OSHA have instituted policies to ensure that employees are protected from exposure to blood and other potentially infectious fluids Use of standard precautions and body substance isolation have been shown not only to reduce the risk of bloodborne pathogens, but also to reduce the risk of transmission of other diseases between patient and health care worker This also reduces the risk of transmission between patients Handwashing still remains the single most effective means of preventing the spread of infection Reducing Risks Related to Occupational Exposure Recommendations for an occupational exposure is to begin antiretroviral therapy with at least 2 or 3 medications Exposed health care worker should begin therapy within 1 to 4 hours following a high-risk exposure For best prophylactic effect, initiation of postexposure prophylaxis must occur within 36 hours Completion of a 4 week course of therapy after an occupational exposure is essential Reducing Risks Related to Occupational Exposure Hospitals or agencies should have policies in place that specifically address occupational HIV exposure because instituting chemoprophylaxis needs to occur immediately Optional HIV testing may be done at 6 wks and 3 months after exposure Maintaining of confidentiality for both exposed health care worker and source patient is of utmost importance Appropriate counseling and necessary referrals should be made for the health care worker and patient when HIV testing is indicated Outlook for the Future Outlook for the Future As we enter the third decade of the HIV pandemic, much has been learned about transmission and ways to prevent infection With no cure in sight, prevention of infection through education, prevention of mother-to-child transmission, and in some cases postexposure prophylaxis can limit the effect this disease has on the human population The field of HIV and AIDS nursing changes frequently, and nurses must constantly refresh their base of knowledge As new therapies emerge, the nurse will be in the unique position to educate patients and the public regarding what is undoubtedly the most challenging infectious disease discovered in the 20th century