Introduction to Health Careers Clay Day Notes Build the Digestive System Part of Digestive Function System Digestive Tract Break down and absorption of nutrients needed for the body to survive. Mouth The mouth secretes enzymes that break down food so they can flow to the esophagus. Esophagus Food goes through a person's throat (AKA: esophagus) to deliver food into the stomach. Introduction to Health Careers~Delaine A. Stendahl Facts and Reminders Digestive tract is a series of __________________ organs joined in a long, _______________ tube from the mouth to the anus—and other organs that help the body break down and absorb food (see figure). Before you even take a bite, your nose ________________it and signals the _____________________, which sends word to the ___________________ controlling your mouth's salivary (spit) glands. Once the glands have their cue, they get busy secreting juices, making your mouth water. When you bite into the sandwich, the salivary glands get even more excited and secrete more saliva, making the ________________moister and easier to swallow. This region prevents the highly acidic stomach "________________" from flowing backward. People who have damage to this portion of the esophagus often suffer from acid ______________. Symptoms can include a severe burning sensation in both the chest and stomach that can be ______________________. Esophagus is made up of stratified squamous cells, which are right before the _________________ ____________________ muscle. As the esophagus meets the stomach, the cells become stratified columnar, which is not _____________ ____________ ________________ cell tissue Chronic acid reflux is a pH of _________. __________________ will wear down the muscle cells and change them to stratified squamous which can cause cancer during Name________________________________ Score_____/63 Steps for Construction Create a long worm out of white clay about ¼ inch in diameter. Lead the worm from the mouth to the liver as shown above. We will do a ‘fake and break’ technique and reconnect at the stomach. Introduction to Health Careers Clay Day Notes Part of Digestive System Function Facts and Reminders Steps for Construction the process of cell change over. Goes ________________ to Cancer. Fat People: Acid reflux happens when the ________________ of the stomach puts pressure when laying down. Aortic rise sits between the esophagus and heart and can suffer from erosion from chronic drinking. If so, it is ________________ immediately. Stomach Produces chime by pushing and churning the contents of the stomach with the gastric juices like a blender to make the food into a usable form. Introduction to Health Careers~Delaine A. Stendahl _____________________________ a house is important because chemical burns in the throat cause scar tissue that makes for problems swallowing their ___________________ life. The stomach is lined with thick _____________ to prevent the stomach muscle from being broken down by the hydrochloric acid in the stomach. Hydrochloric acid is very ________________ which means it ______________. Stomach acids vary in acidity from 1-3 on the pH scale. If you want to lose weight, you need to eat a little less each meal and soon your brain tells your body you are full with less food; the opposite is also true. The stomach does not absorb nutrients. There are 3 things it can absorb___________________ , ______________, ________________. The stomach has three layers of muscle, which are used to churn the contents into chime. After churning, it reorganizes the contents into the nutrients as follows. These are listed in the order they enter the next part of the digestive system… We will create two stomachs, one to use as a model and one to put on your clay person. Take a peanut m&m size of white clay and make a double pointed tear drop. Angle the drops to make an S shape off of the main part of the stomach. Place one stomach on the left side of the lungs and attach a small piece of esophagus to the top portion of the stomach. Take the second stomach and cut it in half lengthwise. Using the lead of a pencil, make three impressions representing the different nutrient sectioning of the digestion process. Line with green clay representing mucus that lines the stomach. Skip to the pancreas construction at this point. Introduction to Health Careers Clay Day Notes Part of Digestive System Liver Function The liver has four main functions. 1. To Make Bile: bile metabolizes everything-bilirubin, cholesterol, and salt. 2. To Store Nutrients: Serve as a ‘grocery store’ to store everything absorbed from the stomach and the intestines. 3. To Detoxify: the liver removes anything that is dangerous from the blood stream; taking it out of circulation in the body. 4. Clotting Factors: Liver will help the blood to clot. Introduction to Health Careers~Delaine A. Stendahl Facts and Reminders Carbohydrates, proteins, fats…remember ____ +_____=_____! Notice that the first food to be digested and enter the blood stream burns the fastest…only 4 calories! That is why sugars give you quick energy but you get hungry again quickly if you do not eat a _______________ meal. A balanced meal provides energy needed at a constant __________. Throw up is reverse peristalsis. After churning, the stomach reorganizes its contents. The liver is a large (largest internal organ), meaty organ that sits on the right side of the belly. Weighing about ____ pounds, the liver is reddish-brown in color and feels _______________ to the touch. Normally you can't feel the liver, because it's protected by the _______ cage. The liver has two large sections, called the right and the left __________. The gallbladder sits under the liver, along with parts of the pancreas and intestines. The liver and these organs work together to digest, absorb, and process food. You need____% of your liver to maintain quality of life. Heard of babies having jaundice? They appear _________________ because the liver is not processing _____________________. The liver is not working efficiently at this point as it breaks up old red blood cells in the baby’s body. Sometimes babies are put under certain ______________ but putting them in ___________________ also helps to break down the bilirubin for the body to break it down easier. Morning sickness is related to _________________ levels that are changing. Steps for Construction Using a peanut M&M size ball of terra cotta clay, make a tongue by creating a short tube and flattening by rolling once. Mark with diagonal lines like searing a steak on the grill. Cut into a teardrop. Using the point of your pen or pencil, make an indenture, which will be the hole for the gall bladder. Your indenture will be in the location indicted by the diagram to the left. This hole will be the duct that leads to the gallbladder. The two sections of the liver are connected with the falciform ligament. Notice we have built only the right lobe at this point. Second lobe (left lobe): Make another small tube with your remaining terra cotta clay and roll to make a tongue. Cut a triangular piece like the diagram and make the diagonal lines again like the right lobe. Put them side-by-side. Introduction to Health Careers Clay Day Notes Part of Digestive System Bile Function Breaks up, dissolves, and digests fats. Introduction to Health Careers~Delaine A. Stendahl Facts and Reminders Steps for Construction Think of the liver as the back of the store. It has stockers who restock the shelves. The trucks are the Hepatic portal or the brain and released as needed. When people take ________________________, the meds go through the blood stream to the liver. The liver will sometimes store them and end their effectiveness and then you would need to take them more than ____________a day. Some drugs must go through the liver to become ______________. Chugging! Alcohol goes straight to the brain ________! NOT GOOD. This will stop what is called the ________ trigger, which is vomiting. VOMITING IS SURVIVAL. The person MAY NOT LIVE! We _________ do ANYTHING about alcohol poisoning. First affects motor, then _______, then sensory systems by slowing them down. If the liver gets continual alcohol it will look like a Nestles __________ bar-good as candy, not as liver! This is called cirrhosis of the liver. Alcohol changes to be less toxic in the liver but still is toxic to the _______. Ethyl alcohol is very dangerous. Too much alcohol causes the brain stem to become __________________ and limits _______ to the brain and leads to alcohol poisoning. It is like a windshield wiper. It sweeps from the __________ of the brain to the back. Alcoholics will __________ and bruise a lot. This is due to lack of Vitamin ____. Marijuana is a CTC and nausea depressant. Liver and lungs often acquire ___________ because their job is to capture toxins with the use of extra enzymes. Stored in the gallbladder. Secreted when food is eaten and used in Bile is stored in the gallbladder so we do not construct anything here. Introduction to Health Careers Clay Day Notes Part of Digestive System Function Gallbladder In response to signals, the gallbladder squeezes stored bile into the small intestine through a series of tubes called ducts. Bile helps digest fats, but the gallbladder itself is not essential. Removing the gallbladder in an otherwise healthy individual typically causes no observable problems with health or digestion yet there may be a small risk of diarrhea and fat malabsorption. Pancreas-a cuboidal exocrine gland Exocrine Function: The pancreas contains exocrine glands that produce enzymes important to digestion. When food enters the stomach, these pancreatic juices are released into a system of ducts that culminate in the main pancreatic duct. The pancreatic duct joins the common bile duct to form the ampulla of Vater, which is located at the first portion of the small intestine, called the duodenum. The common bile duct originates in the liver and the gallbladder and produces another important digestive juice called bile. The pancreatic juices and bile that are released into the duodenum, help the body to digest fats, carbohydrates, and proteins. Endocrine Function: The endocrine component of the pancreas consists of islet cells that create and release important hormones directly into the bloodstream. Two of the main pancreatic hormones are insulin, which acts to lower blood sugar, and glucagon, which acts to raise blood Introduction to Health Careers~Delaine A. Stendahl Facts and Reminders Steps for Construction _________________________. The gallbladder is a small _______________ that sits just under the liver. The gallbladder stores bile produced by the liver. After meals, the gallbladder is ___________ and flat, like a deflated balloon. Before a meal, the gallbladder may be full of bile and about the size of a small ________________. Using green clay, make a pea-size ball of clay and take one strand of green clay from the extruder. The strands will are the ducts that transport bile to the liver. Do not connect the ducts until we have the pancreas. Set-aside for now. The pancreas is located behind the ___________________ and is surrounded by organs including the small intestine, liver, and spleen. It is about six inches long and is shaped like a flat pear. The wide part, called the _________ of the pancreas, is positioned toward the center of the abdomen; the middle section is called the __________ and the body of the pancreas; the thin end is called the ______________and extends to the left side. Several major blood vessels surround the pancreas, the superior mesenteric artery, the superior mesenteric vein, the portal vein and the celiac axis, supplying _____________ to the pancreas and other abdominal organs. Proteins level out glucose levels-So PBJ is better than a _______________! Draw the illustration given in class in open space on the sheet. Look at your palm. Two palms of ________________ to one palm of __________________. Using orange clay the size of a small peanut M&M, create a long teardrop from a ball of clay. Using netting from orange bag, give the pancreas a texture. Shape into a long, thin teardrop. Position the pancreas below the liver as in the illustration. Connect the gallbladder with the clay ducts attaching one to the pencil hole you made in the liver. Attach two more as shown in the illustration. Set the liver, gallbladder and pancreas aside as we will need to attach the intestines before they are put on your figure. Introduction to Health Careers Clay Day Notes Part of Digestive System Duodenum Lesser Omentum Intestines: Cecum Rectum Function sugar. Maintaining proper blood sugar levels is crucial to the functioning of key organs including the brain, liver, and kidneys. The duodenum and pyloric opening join the stomach and the intestines together. The lesser omentum is the portion of interior anatomy that holds both the liver and stomach together. More than just a reservoir for liquids, the cecum is responsible for the absorption of salts and electrolytes into the body from liquids. Another important function of the cecum is to lubricate the solid waste that passes into the large intestine, mixing this waste with mucus. A thick mucus membrane lines the cecum, and produces the mucus necessary to lubricate the solid waste. The cecum is also responsible for breaking down the cellulose fibers from digesting plant matter. The rectum (Latin for "straight") is an 8inch chamber that connects the colon to the Introduction to Health Careers~Delaine A. Stendahl Facts and Reminders Steps for Construction Also known as the small intestine. The small intestine is about 12-20 feet long and about 5 times a person’s height. It is known as the digestive organ. It will take all the material from the stomach and send nutrients out into the blood stream. Think about Quality In and Quality Out. You are only as healthy as the food you choose to eat. High Quality food will give health and longevity! Low Quality food will keep you ___________ but lessen your quality of life and longevity. So, choose your food wisely. MORE ________________ IS BETTER-antioxidants found in fruits and vegetables are key to prevention of cancers. Use a peanut M&M of clay from the scrap clays to make a snake about 1 ½ inches long. Connect one end to the stomach on the right side (lower end.) We will not construct this. The cecum or large intestine will pull ________________ out of the waste and back into the body. If food passes through the intestines too quickly (diarrhea) it will not be firm, as the intestine has not had time to remove the water. Diarrhea and vomiting are the body’s way to remove bad things _______________________. Take a grape size piece of clay scraps and make another long worm of clay about ¼ inch in diameter for the small intestines. Curl up in your hand, but do not roll. Connect one end to the duodenum. Children do not have sphincter control until about ___________ years old. It is Angle the other end of the small intestine toward the anus and thus Introduction to Health Careers Clay Day Notes Part of Digestive System Anus Function Facts and Reminders Steps for Construction anus. It is the rectum's job to receive stool from the colon, to let you know there is stool to be evacuated, and to hold the stool until evacuation happens. When anything (gas or stool) comes into the rectum, sensors send a message to the brain. The brain then decides if the rectal contents can be released or not. If they can, the sphincters (muscles) relax and the rectum contracts, expelling its contents. If the contents cannot be expelled, the sphincters contract and the rectum accommodates, so that the sensation temporarily goes away ______________ to punish young children for not controlling their stools’ and urine. If muscle control is not yet developed, they _________ ‘help it.’ Often ‘potty training’ is a ____________ struggle between child and adult. Children will at times refuse to be trained if parents are too controlling. It is the only thing the parents cannot make a toddler ‘do’ and so the toddler exercises his or her power by controlling their sphincter muscles. If the parent loosens up, children will chose to comply. Disposable diapers have __________________ toilet training of children so now they have created pull-ups where kids FEEL the wetness and then learn sphincter controlquite a ______________________ strategy! The anal sphincters provide fine ________________ of stool. The internal sphincter keeps us from going to the bathroom when we are __________________, or otherwise unaware of the presence of stool. When we get an urge to go to the bathroom, we rely on our external sphincter to keep the stool in until we can get to the toilet. forming the rectum. The anus is the last part of the digestive tract. It consists of the pelvic floor muscles and the two anal sphincters (internal and external muscles). The lining of the upper anus is specialized to detect rectal contents. It lets us know whether the contents are liquid, gas, or solid. The pelvic floor muscle creates an angle between the rectum and the anus that stops stool from coming out when it is not supposed to. The anus is a muscular structure we will not need to construct. How The Digestive System Works - Did U Know? Liver Conditions Hepatitis: Inflammation of the liver, usually caused by viruses like hepatitis A, B, and C. Hepatitis can have non-infectious causes too, including heavy drinking, drugs, allergic reactions, or obesity. Cirrhosis: Long-term damage to the liver from any cause can lead to permanent scarring, called cirrhosis. The liver then becomes unable to function well. Liver cancer: The most common type of liver cancer, hepatocellular carcinoma, almost always occurs after cirrhosis is present. Liver failure: Liver failure has many causes including infection, genetic diseases, and excessive alcohol. Ascites: As cirrhosis results, the liver leaks fluid (ascites) into the belly, which becomes distended and heavy. Gallstones: If a gallstone becomes stuck in the bile duct draining the liver, hepatitis and bile duct infection (cholangitis) can result. Hemochromatosis: Hemochromatosis allows iron to deposit in the liver, damaging it. The iron also deposits throughout the body, causing multiple other health problems. Primary sclerosing cholangitis: A rare disease with unknown causes, primary sclerosing cholangitis causes inflammation and scarring in the bile ducts in the liver. Primary biliary cirrhosis: In this rare disorder, an unclear process slowly destroys the bile ducts in the liver. Permanent liver scarring (cirrhosis) eventually develops. Introduction to Health Careers~Delaine A. Stendahl Introduction to Health Careers Clay Day Notes Problems With and Removal of the Gall Bladder Sometimes, problems arise with the gall bladder, necessitating treatment or even removal. The gall bladder can become irritated and swell up, develop stones or have a blockage in the tunnel running from the gall bladder to the intestines. The gall bladder is only removed when there is a chance that it might burst. If removed, there will no longer be a good flow of bile between the liver and the digestive tract. For this reason, such individuals must be careful about how much fat they eat, and some might also need to take digestive enzymes and bile supplements as well. Party Rules: 1. Don’t go iffy or someone will choose for you. 2. Limit-2 drinks - IF you drink at ALL! Drink before the age of 21 and you are 10 times more likely to become an alcoholic. Brain is greatly influenced by alcohol at an early age! 3. BYO-date rape drugs, demented people 4. Never leave drink unattended 5. Eat foods with fat; alcohol will be absorbed by food, not stomach 6. Never drink punch or eat fruit on the table. It is likely spiked. 7. If someone gives you a drink, dump it-you NEVER know what can be in it! What are stem cells? How are they regulated?-From FDA Stem cells are cells that have the ability to divide and develop into many different cell types in the body during early life and growth. Stem cells may also help repair the body by dividing to replenish cells that are damaged by disease, injury, or normal wear. When a stem cell divides, each new cell has the potential either to remain a stem cell or to become another type of cell with a more specialized function, such as a nerve cell, a skin cell, or a red blood cell. Three types of stem cells have been identified: 1. adult stem cells 2. human embryonic stem cells 3. induced pluripotent stem cells These three types of stem cells share properties: They are capable of surviving over long periods and divide to make additional stem cells. They are unspecialized (“blank slates” that can become specific types of cells). They can develop into specialized cell types (cells that do specific work in the body). Adult stem cells can be found throughout the body. They are found as unspecialized cells among the specialized cells in tissues and organs as well as in umbilical cord blood and peripheral blood (that is, hematopoietic stem cells). An adult stem cell can either divide to make more adult stem cells, or differentiate to produce some or all of the major specialized cell types of the tissue or organ. Human embryonic stem cells (hESC) come from embryos that develop from eggs that have been fertilized in vitro (in a test tube or another artificial environment). Embryonic stem cells can develop into any specialized cell type in the body. Induced pluripotent stem cells (iPS) are generated by reprogramming adult cells that have already differentiated into a specific cell, such as a skin cell. After reprogramming, iPS cells are able to develop into any specialized cell type in the body. Stem cells, like other medical products that are intended to treat, cure or prevent disease, generally require FDA approval before they can be marketed. At this time, there are no licensed stem cell treatments. Source: http://www.webmd.com/digestive-disorders/picture-of-the-liver, www.digestive.niddk.nih.gov/ddiseases/pubs/yrdd/ http://www.ehow.com/howdoes_4565028_the-stomach-work.html, How Does the Gall Bladder Work? | eHow.com http://www.ehow.com/how-does_4672691_gall-bladderwork.html#ixzz2NGTMNDmG http://www.fda.gov/aboutfda/transparency/basics/ucm194655.htm Introduction to Health Careers~Delaine A. Stendahl