Helping Globetrotting Students Travel Safely Kelly Holton Division of Global Migration and Quarantine Centers for Disease Control and Prevention Travelers’ Health Epidemiology 42 40 38 36 34 32 *ITA, includes travel to Canada and Mexico 20 07 20 06 20 05 20 04 20 03 20 02 20 01 30 20 00 Number of Travelers (millions) Number of US Residents Traveling Abroad, 2000-2007 Study-Abroad Students Academic Year Number of Students 1994/95 84,403 1995/96 89,242 1996/97 99,448 1997/98 113,959 1998/99 129,770 1999/2000 143,590 2000/01 154,168 2001/02 160,920 2002/03 174,629 2003/04 191,321 2004/05 205,983 2005/06 223,534 2006/07 241,791 Source: Open Doors (Institute of International Education) Open Doors (Institute of International Education) Leading Destinations of U.S. StudyAbroad Students, 2006/07 United Kingdom Japan Italy Argentina Spain Greece France South Africa China Czech Republic Australia Chile Mexico Ecuador Germany Austria Ireland New Zealand Costa Rica India Source: Open Doors (Institute of International Education) Health Risks to Student Travelers Travelers’ Health Risks Of 100,000 travelers to a developing country for 1 month: – 50,000 will develop some health problem – 8,000 will see a physician – 5,000 will be confined to bed – 1,100 will be incapacitated in their work – 300 will be admitted to hospital – 50 will be air evacuated – 1 will die Steffen R et al. J Infect Dis 1987; 156:84-91 Deaths Related to International Travel Cardiovascular Medical Injury Homicide/Suicide Infectious Disease Other N = 2463 Hargarten S et al, Ann Emerg Med, 1991. 20:622-626 Injury Deaths and International Travel Motor Vechicle Drowning Air Crash Homicide/Suicide Poisoning Other N = 601 Hargarten S et al, Ann Emerg Med, 1991. 20:622-626 Infectious Disease Risks to the Traveler Schistosomiasis Tuberculosis Leptospirosis Polio Yellow Fever Measles Mumps Rubella Tetanus Japanese encephalitis Malaria Diarrhea Leishmaniasis Rabies Dengue Fever Chikungunya Fever Meningococcal Meningitis Varicella Influenza Hepatitis A Hepatitis B ETC. Malaria Mosquito-borne disease Parasite: Plasmodium May lead to severe complications or death ~500 million cases/year worldwide Risk in over 100 countries Prophylactic medication – before, during, and after travel Malaria Risk Areas Yellow Fever Mosquito-borne viral infection – Aedes aegypti Varying severity: – influenza-like syndrome to severe hepatitis and hemorrhagic fever 200,000 YF infections cause 30,000 deaths per year Distribution of Yellow Fever Japanese Encephalitis Flavivirus transmitted via bite of Culex mosquito 50,000 cases and 15,000 deaths yearly Supportive care only Up to 50% of survivors have significant neurologic sequelae Distribution of Japanese Encephalitis Dengue Fever Mosquito-borne flavivirus endemic in most tropical areas of the world No vaccine and no medication for dengue Illness usually mild; it can be severe and cause dengue hemorrhagic (bleeding) fever (DHF) Distribution of Dengue Chikungunya Fever Mosquito-borne disease - primary vector is aedes aegypti Mainly occurs in areas of Africa and Asia Symptoms can include sudden fever, chills, headache, nausea, vomiting, joint pain with or without swelling, lower back pain, and a rash. No specific drug treatment People usually recover on their own; fatalities are rare Hepatitis A Viral infection transmitted via fecal-oral route – Contaminated food and water – Person to person Asymptomatic, or ranges in severity from a mild illness to severely disabling disease lasting months Treatment is supportive Distribution of Hepatitis A Hepatitis B Viral infection transmitted via bloodborne route – Sexual contact – Transfusions, surgical or dental procedures – Shared injection needles Ranges in severity from no symptoms to fulminant hepatitis Treatment is supportive Risk determined by behavior and prevalence of chronic infections at destination Distribution of Hepatitis B Typhoid Acute, life-threatening febrile illness caused by Salmonella enterica serotype Typhi Transmission via fecal-oral route, usually contaminated food or water Chronic asymptomatic carrier Worldwide: 22 million cases and 200,000 related deaths each year Distribution of Typhoid Source: sanofi pasteur MSD Traveler’s Diarrhea > 50% of travelers away from home even for only 2 weeks develop TD ~ 40% will have to alter itineraries ~ 20% will be confined to bed Polio Viral infection Acute onset flaccid paralysis Transmitted via fecal-oral route or pharyngeal spread High transmission areas are India, Pakistan, Afghanistan, Nigeria Polio Risk Areas WHO/POLIO database, as of Sept. 2007 Meningococcal Meningitis Bacterial infection transmitted via the respiratory route Outbreaks in Africa during dry season (December to June) Associated with crowded conditions Distribution of Meningococcal Disease (“Meningitis Belt”) Rabies Acute viral encephalomyelitis Invariably fatal Humans contract rabies by being bitten or occasionally by being scratched by an infected animal 55,000 deaths per year Distribution of Rabies Schistosomiasis Parasite found in some areas of tropical S. America, Africa, and the Far East Second only to malaria in terms of morbidity – over 200 million infected Transmitted while swimming in fresh water lakes, streams, rivers Most will have no symptoms; if exposed, requires testing on return, and then treatment if infected Missionaries and VFRs more likely to be infected* *Nicolls D & GeoSentinal, ISTM 2005 Geographic Distribution of Schistosomiasis Travel Vaccinations Immunizations for Adult Travelers 1. Routine immunizations 2. Required immunizations for travel 3. Recommended immunizations for travel Routine Immunizations Diphtheria Tetanus Pertussis Measles Mumps Rubella Varicella Pneumococcus * Td or Tdap Influenza + MMR Human papillomavirus (HPV) Required Immunizations for Travel Yellow Fever Meningococcal Recommended Immunizations for Travel Hepatitis A Hepatitis B Typhoid Japanese encephalitis Polio Rabies Medications Travel Medications: Prophylaxis & Self Treatment Malaria – chloroquine, atovaquone/proguanil (Malarone), doxycycline, mefloquine (Lariam), primaquine Diarrhea – quinolone (Cipro), azithromycin Altitude sickness – acetazolamide – dexamethasone Motion sickness – scopolamine, dimenhydrinate (Dramamine) Practice Healthy Behaviors Food and Water Precautions Drinks that are bottled and sealed Selection of foods – well-cooked and hot – fruits you can peel Avoidance of – salads, raw vegetables – unpasteurized dairy products – food from street vendors – Ice Handwashing Insect and Mosquito Precautions Protect yourself outside – – – – – Cover exposed skin Use insect repellent Inspect for ticks Treat clothing with permethrin Use pyrethroid coils outdoors Protect yourself inside – Stay in air-conditioned rooms OR – Use window screens – Use permethrin-impregnated bed nets – Use aerosol insecticide indoors Animal Precautions Animal bites and scratches Envenomations – Snakes, scorpions, spiders – Marine animals Avoid all animals, even pets If you are bitten or scratched, seek medical care right away Bloodborne and STD Precautions Prevalence of – – – – STDs Hepatitis B Hepatitis C HIV Unprotected sexual activity Commercial sex workers Tattooing and body piercing Auto accidents Blood products Dental and surgical procedures Environmental Precautions Sun protection Extreme heat and cold – dehydration, heat stroke – hypothermia, frostbite Altitude Water recreation – Drowning, boating, & diving accidents – Risk of schistosomiasis or leptospirosis – Biological and chemical contamination Safety Precautions Wear a helmet Wear seatbelts Drink responsibly Stay alert in crowds Follow local laws and customs Understand local crime risks Travel Health Kit Copy of medical records and extra pair of glasses Prescription medications Over-the counter medicines and supplies – Analgesics – Decongestant, cold medicine, cough suppressant – Antibiotic/antifungal/hydrocortisone creams – Pepto-Bismol tablets, antacid – Band-Aids, gauze bandages, tape, Ace wraps – Insect repellant, sunscreen, lip balm – Tweezers, scissors, thermometer Travel Health Insurance Health insurance may not cover services abroad Consider supplemental health insurance and evacuation insurance US Department of State consular offices can assist in finding medical facilities Health Monitoring Post-travel checkup is recommended for – Long term travelers – Adventure travelers – Expatriates in developing world Post-travel care is recommended for – Fever, chills, sweats – Persistent diarrhea – Weight loss Sources of Information Travel Health Resources CDC Travelers’ Health Website – www.cdc.gov/travel Health Information for International Travel – CDC “Yellow Book” World Health Organization – www.who.int/int International Travel and Health – WHO “Green Book” State Department – travel.state.gov International Society of Travel Medicine – www.istm.org Travelers’ Health Website www.cdc.gov/travel Travel Notices & Announcements Situation Info Advice for Travelers Disease Info Provider Info Resources for more information and Data Sources Destination Pages Study Abroad Information Your Survival Guide to Safe and Healthy Travel Podcasts Questions?