Name of Group Members: Amber and Elizabeth Name of Disorder: Schizophrenia General Description: (Elizabeth) Schizophrenia a serious and long term mental illness that typically begins to appear in men around their late teens and early twenties, and for women in their late twenties and early thirties. This illness changes the way a person sees the world around them and the way they emotionally express themselves. There are four different types of schizophrenia; paranoid, disorganized, catatonic, and undifferentiated. The illness commonly forms in a person through hallucinations, hearing voices (mainly threatening), and disorganized speech. If a person can hear two people talking together or smell scents that others cannot, this is a sign of a bad case of schizophrenia. Schizophrenia can happen in a person if a family member before them has the illness, or it can be caused by their environment. A person with a past relative with schizophrenia is more susceptible to getting the illness by 10%, than a person without. Signs/Symptoms: Emotional: (Elizabeth) Physical: (Elizabeth) Hallucinations and Delusions will cause a schizophrenic person to see things differently (ex. Looking at their best friend and seeing a threatening animal) affecting the way they emotional react towards things (ex. Reacting in fear instead of happiness at seeing their best friend) Grandiosity cause the persons perception of events to be blown out of proportion, believes that things a larger than they really are (ex. Paper cut might be perceived as a lot more serious of an injury and cause hysteria), and the person cannot tell the difference between their perception and reality. Affective Flattening and Alogia is a symptom that causes a schizophrenic person to lack emotional expression. The person will no longer express their emotions through facial expressions or body language, the voice will be very monotone and might not respond well to conversations. However this does not mean that they don’t feel the emotions, they still feel at the same level as a person without schizophrenia. Lack of Personal Hygiene –a person will stop bathing regularly, brushing their teeth, or changing and cleaning their clothing and linens. Oversleeping/ Insomnia –begin to sleep up to 15 hours a day seemingly non-stop, or not sleep for more than 2 hours over a period of three days. Forgetfulness and Difficulty Concentrating –will have a hard time remembering basic tasks and won’t be able to answer spontaneous questions with ease. Depression Social Withdrawal –will no longer attend social events, or regularly keep up with friends and family. Strange Speaking Habits –can be seen through a person rapidly going through multiple topics in a very short amount of time. Making up words that only have meaning to that person. Repeating the same sentence or word multiple times. Avolition causes the person to lack any ambition towards completing projects or daily activities. This is very noticeable in their personal relationships as the person will no longer express no interest in people or social expressions. Inappropriate Effect or “disorganized” is when the person displays the wrong emotions at the wrong time (ex. Laughing at a funeral).This can also be expressed through bouts of anxiety during times that are supposed to be calming, and can further lead to depression. Coming up with non-sensical rhymes. Inability to Cry –physical effect of affective flattening and alogia. Possible Impacts on Life: (Amber) ● loss of contact with family members and/or friends ● homelessness ● become withdrawn no longer willing to participate in things they previously enjoyed, such as sports or music ● cognitive impairment may lead to a drop in grades ● tendencies to withdraw and inappropriate mood behaviours and/or inappropriate behaviours in general may make relationships with other difficult Therapies/Treatments and their Effectiveness: (Amber) ● prior to 1950s, hospitalized for extended periods of time and frequently became institutionalized ● insulin coma therapy (the administration of large doses of insulin to induce coma), electroconvulsive therapy (the application of electrical current to the temples to induce a seizure), and prefrontal lobotomy (a surgical procedure in which the tracts connecting the frontal lobes to other areas of the brain are severed). ● 1950s class of drugs referred to as antipsychotic medications (Typical and Atypical) discovered to be effective in treating schizophrenia. Antipsychotic drugs significantly reduce some of the symptoms of schizophrenia in many patients. ● people taking antipsychotic drugs are only 20% likely to relapse. 80% of people who have stopped taking the antipsychotic drugs are likely to relapse. ● First generation antipsychotics (conventional, or typical antipsychotics) are not normally the first choice to treat schizophrenia due to side effects that can severely affect body movements; however, those who do not respond to second generation antipsychotics (atypical antipsychotics) may respond to first generation antipsychotics. ● Typical antipsychotics are known to induce movement disorders (tardive dyskinesia) in more than 1-in-3 patients. Some movement disorders may be permanent, even after the medication is stopped. Movement side effects can include: ○ Inner restlessness ○ Painful muscle cramps ○ Tremor ○ Involuntary and repetitive movements ● also known to be related to high levels of prolactin (a hormone) in the blood, and a severe neurological side effect known as neuroleptic malignant syndrome (NMS). Blood tests are often required to check for possible problems with this type of schizophrenia treatment. ● Atypical antipsychotic associated with weight gain as well as blood sugar and cholesterol issues. People on these medications can develop type 2 diabetes. Movement disorders can also occur with this type of treatment but they are far less prevalent. ● Other possible treatments may include: ○ Skills training ○ Cognitive behavioral therapy (CBT) – a type of psychotherapy focused on building skills and changing behaviors ○ Cognitive remediation – uses brain exercises to improve the cognitive impairment typical in schizophrenia ○ Social cognition training – focuses on creating an understanding of social relationships and interactions ○ Going to support groups Typical Antipsychotics: ● developed in the 1950s for the treatment of psychosis ● block two types of chemical receptors in the brain – receptors for dopamine and serotonin. ● Chlorpromazine (Thorazine) was the first conventional antipsychotic developed for schizophrenia. ● Conventional antipsychotics, measured via potency when compared to chlorpromazine (Thorazine). Potency of antipsychotic medication indicates how much medication is needed in order to achieve the desired effects to that of 100 mg of chlorpromazine (Thorazine). ● Low potency conventional antipsychotics include: ○ Chlorpromazine (Thorazine) ○ Thioridazine (Mellaril) ● Medium potency conventional antipsychotics include: ○ Loxapine (Loxapac, Loxitane) ○ Molindone (Moban) ○ Perphenazine (Trilafon) ○ Thiothixene (Navane) ○ Trifluoperazine (Stelazine) ● High potency conventional antipsychotics include: ○ Haloperidol (Haldol, Serenace) ○ Fluphenazine (Prolixin) ○ Zuclopenthixol (Clopixol) Atypical Antipsychotics: ● discovered in 1950s, not put into practice until the 1970s ● alter dopamine and serotonin pathways in the brain but do so to a lesser extent. ● The first atypical antipsychotic was clozapine (Clozaril) but it has fallen out of use due to white blood cell side-effect concerns. ● Atypical antipsychotics for schizophrenia include: ○ Aripiprazole (Abilify) ○ Asenapine (Saphris) ○ Clozapine (Clozaril) ○ Lurasidone (Latuda) ○ Olanzapine (Zyprexa) ○ Paliperidone (Invega) ○ Quetiapine (Seroquel) ○ Risperidone (Risperdal) ○ Ziprasidone (Geodon) Antidepressants: ● The two most commonly used antidepressant types are SSRI's and SNRI's Selective serotonin reuptake inhibitors (SSRI) ● Sertraline (Zoloft) ● Escitalopram (Lexapro) ● Fluoxetine (Prozac) ● Citalopram (Celexa) ● Paroxetine (Paxil) Serotonin and norepinephrine reuptake inhibitors (SNRI) ● Duloxetine (Cymbalta) ● Venlafaxine Antianxiety Medications: ● Alprazolam (Xanax) ● Clonazepam (Klonopin) ● Diazepam (Valium) ● Lorazepam ( Ativan) Sources Cited: (use APA format) (Amber) Walker, Elaine F. and Ingraham, Loring J. (2009). Schizophrenia: Background, types, and symptoms. In N. Piotrowski (Ed.), Psychology and Mental Health. Hackensack: Salem. Retrieved November 14, 2015, from http://online.salempress.com Tracy, Natasha (2015, September 27). Schizophrenia Symptoms and Impact on Everyday Life. Retrieved November 14, 2015, from http://www.healthyplace.com Tracy, Natasha (2015, September 27). Schizophrenia Treatments: How do you Treat Schizophrenia? Retrieved November 14, 2015, from http://www.healthyplace.com Tracy, Natasha (2015, September 27). Schizophrenia Medications: Types, Side Effects, Effectiveness. Retrieved November 14, 2015, from http://www.healthyplace.com Bouthner, Gerald (n.d). Schizophrenia. Retrieved November 15, 2015, from http://www.thechallengesofmentalillness.com/p/what-is-schizophrenia.html (Elizabeth) Bengston, M. (2013). Types of Schizophrenia. Retrieved November 16, 2015, from http://psychcentral.com/lib/types-of-schizophrenia/ Joyner, J. (2010, April 13). Emotional Symptoms of Schizophrenia. Retrieved November 16, 2015, from http://www.livestrong.com/article/105744-emotional-symptoms-schizophrenia/ Schizophrenia - Canadian Mental Health Association. (n.d.). Retrieved November 16, 2015, from https://www.cmha.ca/mental_health/facts-about-schizophrenia/ Smith, M. (2015, August 1). Schizophrenia. Retrieved November 16, 2015, from http://www.helpguide.org/articles/schizophrenia/schizophrenia-signs-types-and-causes.htm Our Case Study: Lindsay's Story http://www.rcpsych.ac.uk/mediacentre/pressreleases2012/nationalauditofschizo phreni/casestudies.aspx