Warm-Up
• Write your homework – get it stamped!
• Update your table of contents for today!
• Complete the “Before” column ONLY on the
Anticipation Guide on the front counter and tape
it on to page 14!
Date
Session
#
1/22 &
1/26
7
Activity
Page
#
Anticipation Guide & Background Notes
14
“Milk…How Sweet Is It?” Lab Guide
15
Warm-Up
• What were your answers on the
Anticipation Guide?
• What do you think coevolution is?
• Starting with the next slide, whatever is
in black are the notes you should be
writing!
Coevolution
Coevolution – when 2 (or more)
organisms or things affect each
other’s evolution/evolve together
dependent on each other
Lactose Vs. Lactase Notes
• Lactose = a sugar found only in milk
• Lactase = an enzyme found in the lining
of the small intestine that breaks lactose
down into glucose, which can be digested
by the body
Just FYI…
Enzyme = a substance produced by a living
organism that acts as a catalyst to bring
about a specific biochemical reaction
Lactose Vs. Lactase
• What does lactose intolerance mean?
• So what do you think lactase persistence
means?
• These are genetic characteristics…so, do
you think that it is more likely for people to
be lactose intolerant or lactase persistent?
The Facts About Lactose Intolerance:
Remember, Milk has Sugar, Fats & Proteins!
• Lactose intolerant people cannot digest the sugar (lactose)
in milk because they do not create enough of the lactase
enzyme.
• Because the milk “races through” the digestive system very
little of the other nutrients (fats & proteins) can be
absorbed
Milk – How Sweet Is It? Lab
• Your group will have a sample of the “intestinal
fluid” of a patient. You will test the fluid to
determine if your patient has the gene for lactase
persistence and is able to digest milk.
• Follow the lab directions and share your data with
the class by adding your data to the table on the
board.
• Answer the lab questions on your sheet.
Milk – How Sweet Is It? Lab Roles
• Group Leader – reads all directions and keeps group on
task; reinforces the jobs of others
• Supply Manager/Clean Up – manages supplies & cleans
up after both parts of the lab are complete
• Math & Map Master – does calculations & is in charge of
recording math & map information (someone with a
phone & an agenda to use the map in the front of it)
• Discussion Leader – Leads the discussion of the questions
to share information with the group and the class if
required
Milk – How Sweet Is It? Lab Results
Samples
Patient #1
(Japan)
Patient #2
(Kenya)
Patient #3
(China)
Patient #4
(Italy)
Patient #5
(Papua New Guinea)
Patient #6
(Finland)
Patient #7
(Saudi Arabia)
Patient #8
(Uganda)
2 minutes
Glucose levels
(mg/dL)
Lactose Intolerant or
Lactase Persistent?
Global Distribution
of the
Lactase Persistence Genotype
You will analyze the distribution of lactase persistence
(ability to digest milk) across a large area of the world.
1. Calculate the frequency of lactase persistence for the 3-4
regions on your strip of paper.
2. For each region, you must put a sticker on the board. If the
percentage is less than 40%, place a pink sticker, if the
percentage is equal to or greater than 40%, place a green
sticker.
= lactose intolerance
= lactase persistence
3. When you have the percentages calculated, send your
Math & Map Master to place the stickers on the correct
country on the map on the board.
1. Create a key for the map on your answer sheet.
- Green for lactase persistence (ability to digest milk ≥ 40%)
- Red for lactose intolerance (ability to digest milk < 40%)
2. Using dots or shading, duplicate the class data on the map on your
note guide.
Global Distribution of the
Lactase Persistence Genotype
Answer the activity
questions below the
map
on your note sheet
Got Lactase? The Co-Evolution of Genes & Culture
Got Lactase: The Co-Evolution of Genes and Culture
http://www.hhmi.org/biointeractive/making-fittest-got-lactase-co-evolution-genes-and-culture
https://www.youtube.com/watch?v=umiLaW5AmKg&noredirect=1
• During the video, answer the video questions 1-4
• After the video, go back to the Anticipation Guide from your WarmUp and fill out the “After” column, and then answer question 5.
HOMEWORK:
Answer the reflection
questions on the back
of the note guide by
next class!