DNA STUDY GUIDE! STUDY!!! STUDY!!!! STUDY!!!! 1. WHAT DOES DNA STAND FOR? DEOXYRIBONUCLEIC ACID! 2&3. SUBUNITS OF DNA? NUCLEOTIDE! Made of three parts: Sugar Phosphate Base 4&5. SHAPE OF X-RAY PICTURE OF DNA? Double Helix shape Picture taken by Rosalind Franklin 6. FOUR BASES IN DNA? 7. CHARGAFF’S RULE? ADENINE and THYMINE GUANINE and CYTOSINE Base pairs always match up because they are found in equal amounts! If there is 40% of Adenine there is 40% of Thymine! If there is 20% of Cytosine there is 20% of Guanine! 8. COMPLIMENTARY BASE PAIRS???? Orignal: ATTCGCAGTCCATCTGCA Complimenatry: TAAGCGTCAGGTAGACGT Grilled Cheese and Apple Tart!!!! 10. CHANGES IN THE DNA BASES? Changes in an organism’s DNA bases is called a mutation. There are 3 types of mutations: Deletion – when a base is left out Insertion – when a base is added Substitution – when a base is replaced/changed. TGAGCC changes to TGAGAC what is it????? Substitution of course!!!!! MUTATIONS???? If a mutation is passed on to another generation what type of cell is it found in….sex cell or body cell??????? In a sex cell of course!!!! A sex cell is what gets passed on to a new organism! CAUSES OF MUTATIONS???? Radiation X –Rays Sun exposure Pesticides/Herbicides GENETIC ENGINEERING???? Genetic Engineering is the transfer of genes from one organism to another. Examples include: Genetically modifying food to make it pest resistant or better tasting Cloning organisms Therapeutic cloning to replace damaged cells in an organism. GENETIC ENGINEERING VS. SELECTIVE BREEDING Selective Breeding: Choosing two organisms to sexually reproduce Example: Genetic Engineering: Inserting a gene into a different organism Does not require sexual reproduction DNA REPLICATION!!! DNA copies itself by going through replication. (the beginning of mitosis) Steps to replication: 1. DNA adds the complimentary bases 2. DNA splits down the middle 3. The DNA strand separates and adds new bases to the inside of the original strand. 4. In the end = 2 new identical strands of DNA!!!