Introductory anatomy Objectives Conceptual Overview- what is anatomy/basic terminology: 1. Disciplines: 1. Gross- structures viewed and studied w/o scientific instrumentation 2. Histology-study of micro anatomy, using microscopes 3. embryology-development 4. Clinical- gross in context of structure, function, dysfunction 2. Anatomic position: 1. supine- lying on back 2. prone-lying on front 3. superior-inferior 4. anterior(ventral) posterior (dorsal) 5.lateral-medial 6. distal-proximal 7. superficial- deep 8. internal-external 9. unilateral- only on one side 10. bilateral- structure on both sides 11. ipsilateral- remains on same side as origination 12. contralateral- crosses midline from origination 13. palmar-plantar 3. Planes: 1. Sagittal- paramedial or midsagittal 2. Transverse 3. Coronal-anterior and posterior halves 4. oblique planes 4. terminology of anatomy used to describe location 1. dorsal body cavity- cranial cavity or vault (brain) , vertebral (spinal cord) 2. Ventral body- thorax and abdominal pelvic cavities separated by diaphragm 3. thoracic- pleural cavities (lungs) mediastinum (superior vessels of heart and pericardial cavity heart) 4. abdominal pelvic cavity- abdominal (digestive) pelvic (urinary and reproductive) 5. serious membranes- simple squamous epithelium Visceral- touches organ Parietal- touches wall Serous cavity- fluid in between Other locations: Oral cavity-mouth Nasal- behind nose Orbital- eyes Middle ear- inner ear bones Synovial cavity- synovial joints with synovial fluid Landmarks: Section 2: Skeletal system 1. features of cartilage 2.Functions and types of cartilage 3. Functions of skeletal system 1. Provide support to soft tissues- framework 2. Provides protection for tissue/organs- body cavities 3. Storage- 90% ca and phosphate stores 4. Storage of red bone marrow for hematopoeisis 4. Major divisions of skeletal system Vault- protect brain Ribcage- organs of ventral 5. General bone features 1. about 126 bones 2. Axial (skull, thoracic cage, vert column) and Appendicular skeleton (pectoral girdle, upper limb, pelvic girdle, lower limb) 3. shapes A. long bones- epiphysis (covered by articular cartilage) and shaft (hallow medullary cavity lined with endostium and holds yellow marrow outer membrane of bone is periostium), metaphasis (contains growth plate) b. Short bones- cube shaped- C. Flat bones-thin D. Irregular- unusual shapes E. Sesmoid- small and only in tendons 6. Formation of bone 1. OssificationA. Intramembraneous- when osteoblasts produce bone matrix in mesenchymal tissue locations (flat bones of skull). Begins with ossification center s in thickened mesenchyme which osteoprogenetia, osteoblasts (lay down matrix), woven bone (replaced by lamellar bone), remodeling and replacement of woven bone by compact bone and spongy bone. B. endochondrial- new bone from cartilage models- all long bones- 8-12 weeks of development, formation of bone center, cartilage matrix begins to calcify shaft, blood vessels penetrate, osteoblasts lay down periosteal bone collar, primary ossification center in center diaphysis, acts as a model for new osteoblasts to deposit newly synthesized osteoid, secondary centers in epiphysis, cartilage replaced except hyaline cartilage on ends. 2. Interstitial- bones grow longer (epiphyseal plate and hyaline cartilage in plate cause this) cartilage lay down new material to increase length 3. appositional bone growth- increase in diameter of bone, bone added on surface by osteoblasts in periosteum. As bone deposited, bone next to medullary cavity absorbed by osteoclasts 7. Joint classifications 1. Function- amount of movement between bones 1. Synarthrosis- cant move 2. amphiarthrosis - slightly moveable 3. Diarthrosis- freely immovable 2. Surround or hold 1. Fibrous joint- unites ends of bones with dense connective tissue a. suture-skull synarthrosis b. gomphosis- tooth and jaw synarthrosis c. syndesmosis - dense tissue between two bones as interosseous member- radius/ulna- amphiarthrosis 2. Cartilaginous - utilizes cartilage between bones a. synchondrosis - hyaline cartilage plates between bones- epi plate in growing bones- synarthrosis b. symphysis- fibrocartilage connection between two bones- pubic symphysis, intervertebral discs- ampiarthrosis 3. synovial- joint capsule surrounds ends of bone to hold it together a. double layer Fibrous- outer, creates a cavity Synovial membrane- inner, secrets fluid to joint 8. Structures and types of synovial joints 1. double layer a. Fibrous- outer, creates a cavity b. Synovial membrane- inner, secrets fluid to joint 2. Diarthrosis joints- Ligaments used to help support joint Types: Uniaxial (planar or gliding- pivot- hinge), biaxial (condyloid, saddle), multiaxial (ball and socket) 9. Vasculature and innervation joints 10. Terms associated with movement Flexion (decreases angle) and extension (increase angle), hyperextension (extension beyond anatomic position)Abduction and adduction and circumduction (circle, continuous flexion abduction, extension and adduction in succession) Lateral flexion (vertebral column) Gliding- one flat bone over another flat bone (carpal bones in wrist) Rotation-bone pivots around its axis Lateral and medial rotation Elevation and depression FOOT ONLY Dorsiflexion- movement of ankle dorsum closer to surface of leg Plantar flexion- Sole of foot to posterior surface of leg Inversion- twisting sole inward Eversion-twisting sole outward FOREARM Supination- palm turned anteriorly Pronation- palm turned posterior ANY Protraction and retraction Opposition- thumb towards palm and fingers to hold objects Skin and Fascias 1. Describe the general functions and features of skin. Protection, sensation, absorption, heat regulation 2. Describe types of fascia, composition, and locations. Fascia- connective tissue with ECM from collagen, elastin, reticular fibers help add strength, compartmentalize structures, facilitate movement Superficial fascia Fatty layerDeep layer- membranous Deep/investing fascia Neurovascular sheath Retinacula Fibrous Intramuscular septa Muscle attachments Muscular System 1. Describe all three types of muscle. Skeletal, cardio, smooth 2. Discuss the structures of skeletal muscle. Muscles (epimysium) Fascial (perimysium), Fibers (endomysium) 3. Discuss the general features of skeletal muscle; including naming of muscle. Named for action or function (adductor magnus) Named for body region (flexor digiti minimi) Named for points of attachment (sternocleidomastoid) Named for shape (deltoid) Named for size (magnus, brevis, longus) Named for number of muscle attachments (biceps, triceps) Named for orientation of muscle fibers 4. Discuss basic concepts of muscles functions. Prime mover Antagonist Synergist Fixators Cardiovascular System 1. Describe the components of the cardiovascular system. 1. Heart 2. blood vessels 3. blood- transport nutrients, allows communication (endocrine), protect from infections RBC, WBC, platelets- formed elements Blood plasma- 91% water 7% protein 2% other solutes 1% electrolytes 2. Describe the structure of blood vessels. Larger smaller 3. Compare and contrast the various types of blood vessels with their functions and their wall composition. Tunica intica- endothelium (allows blood to pass w/o obstruction)_ Tunica media- circular layers of smooth (vasoconstriction and dilation) Tunica externa- connective tissue Large elastic (aorta, pulmonary trunk, pulmonary artery) greater TM able to distend and recoil so they maintain blood pressure and conduct blood Muscular arteries more musical layers in TI Small arteries and arterioles- fewer elastic and smaller muscular cell layers begin to lose TE Vasovasorium- network of small arteries in TE of larger blood vessels (own blood supply) Vasoconstriction, vasodilation, baroreceptors (pressure change detectors), chemoreceptors (chem/balance level detector) VEINS 1. Large – all 3 layers, but less smooth muscle than arteries 2. Medium- decrease in TM- major difference VALVES (TI and collagen/elastic structures) 3. Venuoles- drain capillary beds low TM LINKING CONNECTION- capillaries (simple squamous epithelium) 1. continuous- endothelium forms complete continuous lining, connected by tight junctions 2. fenestrated- continuous epithelium and basement membrane, but small holes for passage of molecules 3. sinusoidal- discontinuous, large gaps in endothelium and basement membrane Great vessels- transport blood to and from heart Superior and inferior vena cava- dumps into RA Pulmonary trunk- blood from RV to lungs Aorta- system circuit, from LV to systems of body 4. Define anastomosis and discuss the functional consequences of these vascular connections. 5. Describe the general organization and the flow of blood through the heart. 2 pumps push blood Right side pushes deoxygenated blood to lungs to exchange o2 and co2pulmonary circuit Left side pushes blood to arteries to body- systemic circuit Systemic circuit RA from SV or IF tricuspidRVsemilunar valve pulmonary trunk separates to pulmonary arteries lungs (gas exchange) pulmonary veins- LA bicuspid LVAortic semilunar valve ascending aorta Lymphatic System 1. Discuss the organization of the lymphatic system. Lymph Lymph channels- lymphatic capillaries drain to small lymph vesselslarger vessels Lymph tissue 2. Identify and describe the components of the lymphatic’s system. 3. Discuss the structure and function of lymph nodes. Afferent lymph vessel to node then out of node efferent lymph vessel Lymphocyte production Facilitated by contraction of skeletal, arterial pulse, smooth muscle contraction, respiration movements 4. Describe the general pattern of lymphatic drainage for the body. From lower extremities and left upper extremities and left upper neck- thoracic duct and cisternic chiale (drainage from digestive tract) Right upper extremities, thorax, head and neck– right lymphatic duct Nervous System 1. Distinguish between the divisions of the nervous system, physical and functional. CNS- brain and spinal cord PNS- 12 cranial nerves 31 spinal nerves and associate ganglia Segmental in nature: 31 pairs – 8 cervical, 12 T, 5 L, 5S and 1 C Neuron Cell body or Soma- contains organelles Dendrites- info to soma Axon- signal away from soma Synaptic knobs- contain neurotransmitter for release at synapse 1. Unipolar neuron- Single dendrite 2. Bipolar neuron- single dendrite one soma and axon on other side of soma 3. Multipolar neuron- single axon leaves soma with lots of branching dendrites Function divisions: 1. Sensory- afferent or motor- efferent 2. Voluntary (somatic) or involuntary (autonomic/visceral) Sympathetic- flight of fight Parasympathetic- rest/digest 2. Identify and describe the meninges. Dura mater- thick elastic Epidural space- between dura and periostium of vertebrae Subdural space- potential space due to the next is arachnoid Arachnoid mater- spidery, web like appearance Subarachnoid space- filled with CSF, blood vessels and connective tissue Pia materDenticulate ligaments- extend laterally and touch dura mater and stabilize cord Grey mater- neuron cell bodies and synaptic junctions White mater tracks- many mylinated axons, Ventral/anterior Horn- motor functions Dorsal/posterior horn- sensory functions 3. Describe the general concepts of dermatomes and myotomes and how they are mapped on the body. Dermatomes From segmentations mentioned aboveEach level has a direct innervation to that skin Myotome Motor control for a spinal cord level Sclaratome Innervation of bones 4. Describe organization and structures of the spinal cord and spinal nerves. Spinal canal- Atlas –L2= spinal cord Cervical enlargement C3-T2- brachial plexus Lumbar enlargement L1-s3-lumbar plexus Conus medularis tapering and cauda equine 5. Describe the general organization of the autonomic nervous system. PNS- parasympathetic – rest/digestion SNS- sympathetic- fight or flight 6. Identify and describe the origin of preganglionic sympathetic and the pathway options of the sympathetic fiber. 7. Identify and describe the origin of preganglionic parasympathetic and the pathway options of the parasympathetic fiber. 8. Discuss the anatomic basis for referred pain. Somatic afferent fiber spinal nerve to spinal cord dorsal root dorsal root ganglion dorsal rootlets grey matterInterneuron somatic efferent signal from the ventral horn( cell body) action potential for axon ventral rootlet ventral root spinal nervemuscle Clinical and Surface Anatomy When you have completed this section, you should be able to: 1. Apply anatomic knowledge and understanding to clinical scenarios presented in the chapter (see green boxes).