Cardiovascular System Blood Vessels Circulatory System: Blood Vessels Blood Vessel Circuits Pulmonary Circuit Rt. Ventricle Lungs Lf. Atrium Systemic Circuit Lf. Ventricle Body Organs Rt. Atrium Blood Vessel Types Blood Vessel Order, Type, Location Blood Vessel Connections Blood Vessels in Hemostasis Blood Vessel Histology Artery Types Elastic artery Muscular Artery Artery and Vein Artery, Vein, Nerve [VAN] Artery and Vein Compared Muscular (distributing) arteries / veins Arteriole Microcirculation Capillary Types Continuous Fenestrated Sinusoidal /Discontinuous Function Capillary Types Blood Brain Barrier Fenestrated Capillaries kidneys lungs Blood Vessels: Capillary vs. A. / V. N A V A A = artery V = vein N = nerve N capillary Valves Skeletal Muscle Pumps Vascular (venous) sinuses Define Examples Dural sinuses Coronary Sinus Varicose Veins Pulmonary Circuit Pulmonary Circuit Route Right Ventricle Pulmonary Trunk Rt./Lf. Pulmonary aa Rt./Lf. Pulmonary arterioles Rt./Lf. Pulmonary capillaries Rt./Lf. Pulmonary venules Rt./Lf. Pulmonary veins Left Atrium Systemic Circuit Aortic Arch: Human Specimen Artery and Vein Generalized Aortic Arch Branches Blood Vessels and Nerves of the arm Carotid and Vertebral Arteries External Carotid Artery Branches Carotid Arteries and Vagus Nerve Circle of Willis Cerebral Blood Supply from Willis Basilar and Internal Carotid Arteries Sheep Brain Specimen Abdominal Aorta Arterial Pathways Summarized Venous Return from Upper Body Venous Drainage from Brain Venous Return from the Lower Body Posterior Anterior Posterior Anterior Pulse Points Identify major pulse point areas Define pulse Define pulse pressure How does pulse relate to CO? Determine Blood pressure Special Circulations Anastomosis Heart Brain Kidney Portal Systems Liver Hypothalamus Fetus Anastomosis Define Types Arterial Venous Surgical Function Collateral circulation Coronary Circuit Ascending Aorta Right Coronary Artery Posterior Interventricular a. Marginal a. Left Coronary Artery Anterior Interventricular a. Circumflex a. Cardiac Veins Great Middle Small Coronary Sinus Rt. Atrium Heart Circulation on Models Brain Circulation Arterial Anastomoses Renal and Liver Circulation Overview Renal Hepatic Portal System Hypophyseal Portal System Gut Circulation & Hepatic Portal System Fetal Circulation Dissection Specimens Thorax Thorax and Neck Abdomen Front Limb Hind Limb Blood Flow Formula BF = ^P / R Define Terms BF Pressure Resistance Factors BF Oxygen theory Myogenic theory BP = CO x PR Neural Hormonal Renal R : 8Ln / pi x r to 4th power Length Viscosity Radius Blood Flow Resistance, Pressure, Velocity Peripheral Resistance Vascular diameter Most resistance in small vessels Vascular Length Viscosity Turbulence Rough surface Change in Vessel Diameter Blood Pressure Blood Pressure Factors Neural Baroreceptors ANS Vasomotor centers Cardiac center Chemical Hormonal ADH ANP EPO Gases: pO2, pCO2 Renal Renal Blood Pressure Controls Problems Hemorrhage Circulatory Shock Compensatory Progressive Irreversible Fluid Compartments Fluid Percentage for ECF and ICF Capillary Flow Pressures at Capillary Source Heart = Hydraulic [Hydrostatic; changing] Colloid = Albumin [from liver, constant] Location BV = Capillary [or blood] Tissue Spaces = Interstitial 4 pressures as a result of source + location CHP COP IHP IOP Fluid Compartments Fluid Movement E.M. photo of a Capillary Capillary Exchange Hydrostatic Pressure (HP) Outward force BP from heart directly effects Forces fluid to leave (arterial end) capillary ISCF Osmotic Pressure (OP) Pulling force Proteins in plasma Forces fluid from ISCF capillary (venous end) Capillary Dynamics Net Pressures CHP > COP causing filtration CHP = COP causing no net movement CHP < COP causing absorption IHP is fluid left over from previous CO cycle. Usually zero due to lymphatics IOP is fluid left over due to solids not reclaimed by COP. Usually not a factor due to lymphatic system. Capillary Dynamics Summary Renal Circulation in capillary dynamics Capillary Dynamic Changes Problems Hypertension aneurysm atherosclerosis Metastasis Questions?