Pedigrees (Essential Standard 3) Lesson Summary & Context The purpose of this lesson is to provide application to genetics and inheritance. Pedigrees are used in today’s world to predict the possibility of genetically inherited diseases, for this reason it is important for students to know and understand how those predictions are made. This lesson will focus on how to construct a pedigree, how one is read, and then how one can be used to make predictions. Students will work through a variety of practice problems, and ultimately create a family pedigree that demonstrates inheritance patterns of dominant and recessive traits. North Carolina Essential Standards Essential Standard 3.2: Understand how the environment and/or the interaction of alleles, influences the expression of genetic traits 21st Century Skills Critical Thinking: During the warm-up activity students will be asked to draw a visual of how genetic inheritance occurs. Then throughout the note taking session students will be required to make predictions about pedigrees and how they are used in today’s society and why they are so important in today’s medical field . Student Outcomes (TSWBAT) Lesson 1 The student will be able to label the parts of a pedigree The student will be able to read a pedigree, identifying individuals who have a trait, who do not and who are carriers Students will be able to predict offspring ratios using Punnett squares and then filling in pedigree Students will be able to construct a pedigree Materials Lesson 1 White paper, marker, pencils, rulers Family information for pedigree PowerPoint NOVA video Teaching Activities Lesson 1 Pedigrees (Essential Standard 3) 1. Draw a visual/picture, in notes or on white boards to describe how our traits are inherited and where they come from. Share with your partner (coloring utensils are set out)—7 min 2. Build a pedigree—In an interactive lecture, students will learn how to make, use and read pedigrees. Students will be prompted with questions to consider along the way that will reinforce why the material is important and relevant to them. The note taking session will also include practice problems for students to work out along the way. (20min) 3. NOVA video—on Tay-Sachs (Honors) demonstrates why pedigrees are important and goes a bit more in depth for more advanced students. http://www.pbs.org/wgbh/nova/genome/media/2809_q056_03.html 4. Practice problems- Standard will work to create a pedigree from a written story and then written descriptions. Honors students will do the same assignment and have an additional set up practice problems that will take practice a step further to provide an extra challenge.—20 minutes (standard), 20 min (Honors) 5. Family Pedigree Project—students will take obtained information from their families and use it to construct a three generational family pedigree in regards to common dominant and recessive traits. –remaining time Assessments Formative Assessments Practice Problems Predictions made along the way Summative Assessment Family Pedigree Project Weekly quiz Modifications/Enrichments Students will receive the required materials as mandated by their IEP or LEP, for the majority of these students this requires a copy of teacher notes and PowerPoint slides. Honors students will also be required to complete all activities, where as the standard class will be offered a few for extra credit points.