Anatomy & Physiology An Introduction to Anatomy & Physiology Chapter 1 pp. 2-27 Characteristics of Living Organisms 1) Responsiveness: respond to changes in the environment • • 2) 3) 4) 5) irritability – immediate environment adaptability – over a long period Growth – in size or # of cells Reproduction Movement – internal and external Metabolism: series of complex chemical reactions that provide energy for all the other characteristics Anatomy vs. Physiology Anatomy: study of internal and external structures and their relationships Physiology: study of how living organisms perform their vital functions What is the Anatomy and Physiology of an automobile? Anatomy Two divisions: 1) Microscopic – structures that cannot be seen without magnification • Cytology: study of individual cells • Histology: study of tissues, or groups of specialized cells working together 2) Macroscopic (Gross) – structures that are visible to the naked eye • Surface anatomy: study of general form and superficial markings • Regional anatomy: study of all the superficial and internal features in a specific region of the body Physiology • Many different specialties (human, cell, individual organs) • Pathological Physiology (Pathology): study of the effects of diseases on organ system functions Levels of Organization Have you ever heard of “nesting dolls?” Levels of Organization Question: Why should we study activity at the cellular level? Answer: Damage at any of the levels can affect those levels above and/or below. They are interconnected. Example: Genetic Heart Defect Homeostasis Definition: existence of a stable internal environment NECESSARY FOR SURVIVAL!! Homeostatic Regulation: physiological adjustments systems make to maintain homeostasis Question: What happens when homeostatic regulation breaks down? Answer: DISEASE Process of Homeostatic Regulation Step 1: Receptor (ex. nerve ending) responds to a stimulus and sends info to control center Step 2: Control center (ex. brain) processes the information from the receptor and coordinates response Step 3: Effector (ex. gland) responds to the commands of the control center to oppose or enhance the stimulus Example: Regulating Room Temperature Weymouth High School Feedback: A Method of Homeostatic Regulation Negative feedback: a variation outside normal limits (set point) triggers an automatic response that corrects the situation (within normal limits) – MOST COMMON IN BODY Example: Thermoregulation, glucose regulation (Teeter-totter) Positive feedback: initial stimulus produces a response that reinforces the stimulus – ONLY A FEW EXAMPLES IN BODY Example: Blood clotting, Birth (Dominos) Anatomical Landmarks • Helps in remembering the names of multiple structures • Provides the location for multiple structures Anatomical Landmarks The Language of Anatomy Anatomical Position: human form standing with hands at sides and the palms facing forward Supine: lying face up in the anatomical position Prone: lying face down in the anatomical position The Language of Anatomy Anatomical Directions Anterior/Ventral: the front or belly side of the body Posterior/Dorsal: the back of the human body Remember, LEFT and RIGHT refer to the body of the subject and not the observer. The Language of Anatomy Anatomical Directions Cranial/Cephalic: toward the head Caudal: toward the tailbone (coccyx) Superior: above, or toward the head Inferior: below, or toward the feet The Language of Anatomy Anatomical Directions Medial: toward the center of the body Lateral: away from the center of the body Proximal: toward the attached base (typically used for limbs) Distal: away from the attached base (typically used for limbs) The Language of Anatomy Anatomical Directions Superficial: at or near the body surface Deep: farther from the body surface Anatomical Directions The Language of Anatomy Anatomical Regions Body is divided into 4 regions by lines that intersect at the bellybutton (umbilicus) 1) 2) 3) 4) Right Upper Quadrant (RUQ) Right Lower Quadrant (RLQ) Left Lower Quadrant (LLQ) Left Upper Quadrant (LUQ) Clinicians use even more specific distinctions, including 9 abdominopelvic regions. (Thank goodness!) Anatomical Regions The Language of Anatomy Planes and Sections Definition: slice through a 3-dimensional object divides the body into sections (important in non-invasive diagnostic testing procedures) Transverse: perpendicular to the head-foot axis of the body (parallel to the floor while standing; divides the body into superior and inferior sections Frontal/Coronal: parallel to the head-foot axis and extends side to side; divides the body into anterior and posterior sections Sagittal: parallel to the head-foot axis and extends front to back; divides the body into left and right sections **Mid-sagittal refers to a midline division creating equal left and right halves.** Anatomical Planes Planes and Sections Which planes create these “slices”? The Language of Anatomy Body Cavities Functions: 1) Protect delicate organs, by cushioning them during movement (fluid sacs) 2) Permit for size/shape changes of organs without disrupting the activities of surrounding organs Dorsal: surrounds the brain and spinal cord Ventral: much larger, surrounds organs of the respiratory, cardiovascular, digestive, urinary, and reproductive systems (viscera) The Language of Anatomy Dorsal Cavity in Detail 1) Cranial Cavity (Skull) 2) Spinal Cavity (Spine) The Language of Anatomy Ventral Body Cavity in Detail 1) Thoracic Cavity A. Pericardial Cavity (heart) B. Two Pleural Cavities (lungs) 2) Abdominopelvic Cavity (Peritoneal Cavity) A. Abdominal Cavity (stomach, liver) B. Pelvic Cavity (reproductive organs) Body Cavities Introduction to Organ Systems Integumentary • Forms the external body covering • Protects deeper tissue from injury • Synthesizes vitamin D • Location of cutaneous nerve receptors and glands • Major Components: Skin, Hair, Nails Skeletal • Protects and supports body organs • Provides muscle attachment for movement • Site of blood cell formation • Stores minerals • Major Components: Bone, Cartilage, and Ligaments Muscular • Allows locomotion • Maintains posture • Produces heat • Major Components: Muscles and Tendons Nervous • Fast-acting control system • Responds to internal and external changes (stimuli) • Directs activities of other organ systems by activating muscles and glands • Major Components: Brain, Spinal Cord, and Peripheral Nerves Endocrine • Slow-acting control system • Secretes regulatory hormones which direct activities of other organ systems • Growth • Reproduction • Metabolism • Major Components: Glands, Kidneys, Pancreas, Gonads Cardiovascular • Transports materials in body via blood pumped by heart including: • Oxygen • Carbon dioxide • Nutrients • Wastes • Major Components: Heart, Blood Vessels, Blood Lymphatic • Returns fluids to blood vessels • Disposes of debris • Involved in immunity • Major components: Tonsils, Lymph Vessels, Lymph Nodes, Spleen and Thymus Respiratory • Keeps blood supplied with oxygen • Removes carbon dioxide • Major Components: Air passageways, Lungs Digestive • Breaks down food • Allows for nutrient absorption into blood • Eliminates indigestible material • Major Components: Food passageways, Stomach, Intestines, Liver, Pancreas Urinary • Eliminates nitrogenous wastes • Maintains acid – base balance • Regulation of water and electrolytes • Major Components: Kidneys, Bladder, Urine passageways Reproductive • Production of sex cells and sex hormones • Production of offspring • Major Components: Testes and Penis (Male)/Ovaries, Uterus, Vagina (Female) Interrelatedness of Organ Systems Just as one level of organization is dependent on another, organs of different systems rely on the function of the others! Essential Requirements for Survival 1) Nutrients • Chemicals for energy and cell building • Includes carbohydrates, proteins, lipids, vitamins, and minerals 2) Oxygen • Required for chemical reactions 3) Water (60-80% of body weight) 4) Stable body temperature 5) Appropriate atmospheric pressure Radiological Procedures X-ray: high-energy radiation is sent through body tissues to a photographic plate • “radiodense” tissues such as bone appear white, while air appears black Barium-contrast: dense liquid is used to see tissues that are normally difficult to see with x-ray, such as stomach and intestine X-ray X-ray Barium-Contrast Radiological Procedures CAT Scan: x-ray source rotates around the body to show three-dimensional relationships between body tissues MRI: body is surrounded by a magnetic field, atoms of different tissues release different amounts of energy forming an image; more detailed than a CAT Scan Ultrasound: sound waves are sent through the skin, the echoes that are reflected by internal structures form an image CT Scan CT Scan CT Scan PET Scan MRI MRI MRI MRI Ultrasound Ultrasound