Schizophrenia “Schizophrenia...remains ones of the most frightening diseases known to mankind. To an observer, the bizarre behaviors and speech of a schizophrenic are disturbing. For the schizophrenic, the world is a confusing maze of nightmares from which one cannot wake up.” 2 Schizophrenia About Schizophrenia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .4 Definitions History Causes Epidemiology Additional Information Symptoms . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .8 Positive Negative Cognitive Affective Subtypes of Schizophrenia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .10 Paranoid Subtype Disorganized Subtype Catatonic Subtype Undifferentiated Subtype Residual Subtype Phases of Schizophrenia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12 Acute phase Stabilization phase Stable phase Diagnostic Criteria . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .13 Prognosis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 16 Specific Needs . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 16 Treatment . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .17 Medication Therapy TR Implications . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .23 References . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 25 3 About Schizophrenia Definitions: “A severe mental disorder characterized by some, but not necessarily all, of the following features: emotional blunting, intellectual deterioration, social isolation, disorganized speech and behavior, delusions, and hallucinations.” - Dictionary.com “A psychotic disorder characterized by loss of contact with the environment, by noticeable deterioration in the level of functioning in everyday life, and by disintegration of personality expressed as disorder of feeling, thought (as delusions), perception (as hallucinations), and behavior —called also dementia praecox” - Merriam-Webster Dictionary “A psychotic disorder (or a group of disorders) marked by severely impaired thinking, emotions, and behaviors. Schizophrenic patients are typically unable to filter sensory stimuli and may have enhanced perceptions of sounds, colors, and other features of their environment. Most schizophrenics, if untreated, gradually withdraw from interactions with other people, and lose their ability to take care of personal needs and grooming.”- Farlex Medical Dictionary History: In 1893, Schizophrenia was first identified by German psychiatrist, Emil Kraepelin. Before Kraepelin, doctors had divided this mental disorder into three types. The first “disorder,” hebephrenia, which is characterized by extremely disorganized thoughts and difficulty carrying a rational conversation. The second, 4 catatonia, involves unmoving in bizarre positions. The third, paranoia, comprises of an obsession that people or things are out to harm the individual. Kraepelin combined these three categories into a single disease and named it Dementia Praecox, which roughly translates to “demented early” because it was seen predominantly adolescents. Kraepelin believed that schizophrenia stemmed from deterioration in the brain. Swiss psychiatrist Eugen Bleuler noted that some people recovered from this disease for no apparent reason, thus it was not a degeneration of the brain. In 1911, Bleuler renamed the disease to the current term “schizophrenia” because he believed it involved a psychological splitting. “Schism” is Greek for split” and “phrenic” refers to the mind or brain (Abramovitz, 2002, p.16). It is important to note that schizophrenia is NOT the same as split-personality disorder, which is a common misconception prevalent in our society today. Causes: “Ever since schizophrenia was identified as a disease, experts have debated its causes” (Abramovitz, 2002, p. 28). Some scientists believed the onset of schizophrenia came from biological factors in the brain. Others supported the idea of psychological abnormalities as the main cause, and still others held that social and environmental factors were to blame. Sigmund Freud, a well-known psychologist from Vienna believed that a person’s unconscious memories of traumatic childhood experiences caused schizophrenia. After studying the disease extensively, Dr. Frieda Fromm-Reichmann, a German 5 psychiatrist and contemporary of Freud, connected the development of schizophrenia in adolescents to a cold and distant mother (Abramovitz, 2002, pg. 28). Schizophrenia has also been studying in relation to genetics, family ties, brain abnormalities, prenatal damage, and neurotransmitters. A 1920 U.S. study using twin pairs found that schizophrenia developed in identical twins 58% of the time. In comparison, only 15% of the fraternal twins did (Abramovitz, 2002, p. 31). In addition to genetics, there has also been a case made for family ties. According to Abramovitz, people with one schizophrenic parent were 8-18% more likely to develop schizophrenia themselves. People with two schizophrenic parents were 46% more like to develop it in later years (Abramovitz, 2002, p. 32). In regards to brain abnormalities, people with schizophrenia have decreased size in the hippocampus which affects the ability to learn, and decreased size in the amygdala which controls aggression and sensory and emotional processing (Abramovitz, 2002, p. 35). Prenatal damage to the brain may also play a significant role in the onset of schizophrenia. Abramovitz states, “There is considerable evidence that difficult childbirth may result in brain damage associated with the disease in an individual who are predisposed to schizophrenia because of heredity.” Breech birth, the use of forceps during delivery, prolonged labor, and lack of oxygen to the fetus are all associated with high incidence of schizophrenia in later life (Abramovitz, 2002, p. 36). Researchers are currently looking more closely at the role neurotransmitters play in the brains of people with schizophrenia. PET scans show that people with 6 schizophrenia have abnormal levels of neurotransmitters in the brain compared to the brains of those who do not have the condition. They especially have excesses of dopamine. When researchers gave injections of dopamine to clients in a study their symptoms worsened considerably (Abramovtiz, 2002, p. 40). Epidemiology: Epidemiology is the trends and cultures an illness or disease has in a group or society. Schizophrenia effects 1% of US Citizens, which is rising each year with 1.5/10,000 people being diagnosed and effects more men than women (1.4:1). The onset of schizophrenia happens between the ages 21-25 for males and 25-32 for females. (Javed, 2010). Those who have been diagnosed with Schizophrenia are also usually found to live in urban areas, immigrated at some point in their lives, have obstetrical complications, and were born in either late winter or early spring-time birthday (potentially due to influenza exposure during neural development.) Lastly, about ⅓ of homeless adults in the US suffer from Schizophrenia. This is not because homelessness leads to this illness, but that those who suffer from schizophrenia end up on the streets. Additional Information (facts, demographics, statistics, history): Schizophrenics are more prone to early death from infections, heart disease, diabetes, breast cancer, and other illnesses. Experts believe this is because medical personnel are more likely to ignore schizophrenic’s 7 complaints because they believe they are imaginary and a result from the person’s mental malfunctions. 10 to 13% of schizophrenics commit suicide as a result of being depressed with the prospect of living with an endless cycle of terror. (Abramovitz, 2002, p.11) One of the major challenges doctors face with this severe mental disorder is convincing the person that they do need help. (Abramovitz, 2002, p. 12) Schizophrenia is a chronic, severe, debilitating mental illness that affects about 1% of the population, more than 2 million people in the United States alone. Schizophrenia is considered the most chronic, debilitating, and costly mental illness People with schizophrenia are far more likely to harm themselves than be violent towards the public. Symptoms Symptoms of schizophrenia are divided into four classifications. They are as follows: Positive: This category includes psychotic delusions, which are the most common symptom of schizophrenia. It also includes hallucinations. Hallucinations involve 8 hearing, seeing, or sensing things that do not actually exist in reality. Auditory hallucinations are most common and usually involve the individual hearing voices inside their head that they perceive to be real. In addition to hallucinations, persons displaying positive symptoms of schizophrenia may also exhibit inappropriate behaviors such as laughing at the news of a tragedy, undressing in public or in front of strangers, walking in repeated motions or patterns, shaking the head, rolling the tongue, jerking the arms and legs, and stumbling and knocking things over (Abramovitz, 2002, p. 13-14). Negative: This category includes the absence of behaviors and emotions present in normal people. Some examples of this would be lack of facial expressions, lack of automatic movements (blinking, swinging arms when walking), refusal to make eye contact, refusal to speak or speaking very slowly, and failure to experience emotions such as happiness or sadness (Abramovitz, 2002, p. 14). Cognitive: This category includes problems with thought processes. Individuals who display this symptom type experience difficulty in making sense of information, difficulty with focus, as well as memory problems. 9 Affective: This category involves changes in an individual’s mood. Depression and mood swings are common occurrences with this symptom. Odd behaviors such as these, however, may eventually lead to social aversion and painful isolation. Subtypes of Schizophrenia Paranoid Subtype: Paranoid schizophrenia is the most common type diagnosed. This type is characterized by the presence of auditory hallucinations or prominent delusional thoughts about persecution or conspiracy. However, people with this subtype may be more functional in their ability to work and engage in relationships than people with other subtypes of schizophrenia. They are very suspicious of their surroundings and those they interact with Tend to be more functional in their ability to work and engage in relationships Symptoms usually not exhibited until later in life, therefore the person has already achieved a higher level of functioning before the onset of their illness. Hallucinations and delusions typically revolve around a characteristic or theme Tend to exhibit anger, anxiety, and argumentativeness 10 Disorganized Subtype: Disorganized schizophrenia is characterized by the disorganization of the thought process. Because of this difficulty processing thoughts and expressing ideas they seem childlike and incompetent in maintaining activities of daily life. Hallucinations and delusions not usually present Significant impairments on routine tasks such as dressing, bathing, brushing teeth, etc. Appear to be emotionally unstable Child-like behavior Inappropriate laughter/emotions (flat affect) Incoherence in speech Repetitive behaviors Catatonic Subtype: Catatonic schizophrenia is characterized by disturbances in movement commonly seen in a state of inactive, rigid posture. Agitation Decreased sensitivity to pain Inability to take care of personal needs Repetitive purposeless actions Parrot-like repeating of what others are saying or doing 11 Negative feelings Socially withdrawn Motor disturbances, such as unusual facial contortions or limb movements Rigidity Stupor Remain in poses/positions for abnormal amounts of time, exhibiting considerable physical strength (waxy flexibility) Undifferentiated Subtype: Undifferentiated schizophrenia is classified as the patient contains the general criteria for schizophrenia but does not conform to one of the above subtypes. They exhibit features of multiple subtypes without a clear dominance in one. Residual Subtype: Residual schizophrenia is classified when the person is no longer suffering from delusions, hallucinations, or disorganized speech and behavior, but lacks motivation and interest in day-to-day living. Phases of Schizophrenia In addition to sub-types, there are also phases of schizophrenia. (Abramovitz, 2002, p. 21-22) 12 Acute phase: This phase includes active symptoms such as hallucinations, delusions, catatonia, disorganized thoughts, and negative symptoms. This phase can last anywhere from a few hours to several years. Stabilization phase: This phase occurs when acute symptoms decrease and the person regains the ability to function more or less normally. This phase lasts anywhere from six months or more. Stable phase: This phase occurs when symptoms are absent or much less severe than in the acute phase. It is important to note that not all patients will get past the acute phase and that others can remain in the stable phase for a stretch of time. Diagnostic Criteria Most psychiatrists today base their diagnosis on the length of time a patient has had symptoms of schizophrenia. They also examine and take into account how severe the symptoms are. Psychiatrists refer to the fourth edition of the Diagnostic and Statistical Manual of Psychiatry (aka DSM-IV) to make a 13 diagnostic. In order to be diagnosed as having schizophrenia, an individual must display one of the following: The patient must have some psychotic symptoms for at least 6 months The patient must have two or more active symptoms for at least one month The patient must have an inability to interact with others and work productively (Abramovitz, 2002, p. 23-24). Diagnoses can be influenced by culture. For example, doctors in India are less likely to diagnose someone as schizophrenic because they believe someone who experiences hallucinations and other delusions is a spirit medium or avatar who permanently takes on the role of a Hindu god. Likewise, in Japan doctors are less likely to diagnose someone as schizophrenic even if they display the symptoms because of a strong cultural aversion to do anything that might reflect negatively on the patient’s family. They especially want to avoid the stigma of mental illness (Abramovitz, 2002, pg. 25). As far as tests go, there is no test that can make a diagnosis for schizophrenia. According to WebMD, “People with schizophrenia usually come to the attention of a mental health professional after others observe them behaving strangely. Most people with schizophrenia will have at least some of its main symptoms” (WebMD, 2012). For a psychiatrist to make a confident schizophrenia diagnosis, some of these symptoms should be present: Hallucinations. This means hearing voices or other sounds that aren't there or seeing things that don't exist. 14 Delusions (unshakeable beliefs that aren't true). Disorganized speech and behavior (talking and acting strangely). Lack of motivation and emotional expression. Lack of energy. Poor grooming habits. Specific forms of the main symptoms, when present, make a schizophrenia diagnosis more likely. These include: Hearing your own thoughts spoken aloud. Feeling that thoughts are being inserted into your mind, or removed from it, by an outside force. Feeling like other people can read your mind. Feeling that an outside force is making you feel something, want something, or act in a certain way. Hearing voices discuss you or argue about you. Hearing voices narrate your actions as you perform them. A person experiencing schizophrenia may describe these symptoms openly. A psychiatrist may also assume they are present based on observations of a person's speech and behavior. (WebMD, 2012). 15 Prognosis “One important prognostic sign is the patient's age at onset of psychotic symptoms. Patients with early onset of schizophrenia are more often male, have a lower level of functioning prior to onset, a higher rate of brain abnormalities, more noticeable negative symptoms, and worse outcomes. Patients with later onset are more likely to be female, with fewer brain abnormalities and thought impairment, and more hopeful prognosis. The average course and outcome for schizophrenics are less favorable than those for most other mental disorders, although as many as 30% of patients diagnosed with schizophrenia recover completely and the majority experience some improvement. Two factors that influence outcomes are stressful life events and a hostile or emotionally intense family environment. Schizophrenics with a high number of stressful changes in their lives, or who have frequent contacts with critical or emotionally over-involved family members, are more likely to relapse. Overall, the most important component of long-term care of schizophrenic patients is complying with their regimen of antipsychotic medications.” -Flexar Medical Dictionary Specific Needs People living with schizophrenia need a correct diagnosis and early treatment of their illness. They need understanding, compassion, respect, and an effective, functioning mental health system. Like anyone else living with a 16 serious, ongoing illness, a person living with schizophrenia needs help with the fear and isolation associated with this illness as well as the negative cultural attitudes surrounding it. Some who live with this illness need help with their physical care, as dealing with schizophrenia can make even the everyday tasks of life difficult, from staying clean and eating well to following medical treatment. Many people with schizophrenia need long term help with basic needs. Treatment Schizophrenia is considered a lifelong condition which rarely is “cured”, but rather treated. Over the years, medication has proven to help manage schizophrenia’s symptoms, that does not, however, mean that medicine is the only part of the overall treatment of this illness. Successful treatment of schizophrenia depends upon a lifelong regimen of both medication and psychotherapy. The therapy is needed to help the person find a job, learn to be effective in social relationships, increase the individual’s coping skills, and help them learn to communicate and work well with others. Medication: Antipsychotic medications have been found to be most successful in the treatment of schizophrenia. These medications have been found to effectively alleviate the positive symptoms of schizophrenia. People respond differently to 17 the drugs, so sometimes it is necessary to try several different kinds before the right one is found. In light of the lifelong nature of schizophrenia, it requires a lifelong need for medication to keep their symptoms under control. Most often patients are started on a high dose of medication to bring their symptoms under control. Then over time their doctors are able to reduce that dosage to a lower level, which is still able to maintain control over those symptoms and prevent future episodes. Several side effects have been observed, but tend to go away after the first days. Symptoms in first days: Drowsiness Dizziness Blurred vision Develop a rapid heartbeat Menstrual problems Sensitivity to the sun Skin rashes New drugs, called atypical antipsychotics, have been developed to help alleviate some of the side effects of older drugs. 18 Atypical Antipsychotics: Clozapine Risperidone Olanzapine Quetiapine Sertindole Ziprasidone Some side effects of these drugs include: Weight gain Metabolic changes Increased risk of diabetes High cholesterol Drowsiness Restlessness Slowed movements Shakes Long term use can cause an increased chance of Tardive Dyskinesia, an untreatable movement disorder Therapy: Psychosocial treatments can help patients who are already stabilizing on 19 antipsychotic medications deal with communication, motivation, self-care, work, and establishing and maintaining relationships with others. Learning and using coping mechanisms to address these problems allows people with schizophrenia to attend school, work, and socialize. A positive relationship with a therapist gives the patient a reliable source of informations, sympathy, encouragement, and hope. There are several different types of therapy, which include family psychoeducational, assertive community treatment, substance abuse treatment, social skills training, supported employment, cognitive behavioral therapy, and weight management. Self-help groups and networking are also used as a therapeutic method for support and comfort. Family psycho-educational: Patients with schizophrenia are often discharged from the hospital into the care of their family. In addition to educating family members about the symptoms, course, and treatment of schizophrenia, this form of treatment consists of providing family support, problem-solving skills, and access to care providers during times of crisis. When this intervention is consistently provided for at least several months, it has been found to decrease the relapse rate for the individual with schizophrenia and improve the person’s social and emotional outcomes. Also, the burden that family members experience as a result of having a loved one with schizophrenia is lessened. Family members tend to be more knowledgeable about the disorder and feel more supported by the professionals 20 involved, and family relationships are improved. Assertive community treatment: This intervention consists of members of the patient’s treatment team meeting with that individual on a daily basis, in community settings, for example, home, work, or other places the patient frequents, rather than in an office or hospital setting. The treatment team is made up of a variety of professionals. This can include a psychiatrist, nurse, case manager, employment counselor, and a substance abuse counselor. Assertive community treatment (ACT) tend to be successful in reducing how often people with schizophrenia are hospitalized or become homeless. Substance abuse treatment: Providing medical and psychosocial interventions that address substance abuse should be an integral part of treatment as about 50% of individuals with schizophrenia suffer from some kind of substance abuse or dependence. Social skills training: Social skills training is also referred to as illness management and recovery programming and involves teaching clients ways to handle social situations appropriately. It often involves the person scripting situations that occur 21 in social settings in order to prepare for those situations when they actually occur. As part of illness management they are taught basic facts about schizophrenia helping them to make informed decisions about their care and monitor early warning signs of relapse. This treatment type has been found to help people with schizophrenia resist abusing drugs, as well as improve their relationships with healthcare professionals and coworkers. Supported employment: This intervention provides supports such as a work coach, someone who counsels the client in the workplace, as well as instruction on constructing a resume, interviewing for jobs, and education and support for employers to hire individuals with chronic mental illness. Supported employment has been found help schizophrenia patients secure employment, earn more money, and increase the number of hours they are able to work. Cognitive behavioral therapy: Cognitive behavioral therapy (CBT) is a reality-based intervention that focuses on helping a client understand and change patterns that tend to interfere with his or her ability to interact with others and otherwise function. CBT is useful for patients with symptoms that persist even with the use of medication. This method teaches patients how to test the reality of their thoughts and perceptions, how to “not listen” to their voices, and how to shake off the apathy that often immobilizes them. It appears to be effective in reducing the severity of symptoms 22 and decreasing the risk of relapse. Weight Management: Educating people with schizophrenia about weight gain and related health problems that can be a side effect of some antipsychotic and other psychiatric medications has been found to be helpful in resulting in a modest weight loss. That is also true when those with schizophrenia are provided with behavioral interventions to assist with weight loss. Self-Help Groups and Networking: By using these methods they can see that they are not alone in dealing with schizophrenia and feel less isolated. These groups are for people with schizophrenia and their families. Professional therapists are not involved, leaving those with schizophrenia and their families to take charge and run the groups. TR Implications Therapeutic recreation can be used as an effective treatment to reduce the symptoms of schizophrenia and improve the quality of life for those dealing with it. 23 Benefits therapeutic recreation can offer a person with schizophrenia: Learn how to manage stress and coping strategies Aid in sharing thoughts more easily Learn to enhance friendships and relationships Find activities to enjoy during free time Rehabilitation Help learn skills necessary to be successful and home, work, or school Meaning and purpose in life can help people avoid indulging in their delusions 24 References Abramovitz, M. (2002). Diseases and disorders: Schizophrenia. (pp. 8-40). San Diego, CA: Lucent Books. Bengston, M. (2006). Types of Schizophrenia. Psych Central. Retrieved from http://psychcentral.com/lib/2006/types-of-schizophrenia/ Edwards, R.D. (2011). Schizophrenia. Retrieved from http://www.medicinenet.com/schizophrenia/page5.htm Farlex. (2012). Schizophrenia. The Free Dictionary: Medical Dictionary. Retrieved from http://medical-dictionary.thefreedictionary.com/ Schizophrenia Fischer, B. & Buchanan, R. (2012). Schizophrenia: Epidemiology and Pathogenesis. Wolters Kluwer Health. Retrieved from http://www. uptodate.com/contents/schizophrenia-epidemiology-and-pathogenesis Grohol, J. (2011). Schizophrenia treatment. Retrieved from http://psychcentral.com/disorders/sx31t.htm Javed, M. (2010). Gender and Schizophrenia. Journal of Pakistan Medical Association. http://www.jpma.org.pk/full_article_text.php?article_id=2907 Smith, M., & Segal, J. (2012). Schizophrenia: Understanding the signs, symptoms, and causes. Retrieved from http://www.helpguide. org/mental/schizophrenia_symptom.htm WebMD. (2012). Schizophrenia diagnosis. Retrieved from 25 http://www.webmd.com/schizophrenia/guide/schizophrenia-tests (2012). Schizophrenia. Merriam-Webster: An Encyclopedia Britannica Company. Retrieved from http://www.merriamwebster.com/dictionary/schizophrenia (2012). Schizophrenia. Dictionary.com. Retrieved from <http://dictionary. reference.com/browse/schizophrenia> 26