Additional file 2. Diagnostic performances of physical test-hip pathology combinations included in review Article Title: A systematic review of the diagnostic performance of orthopedic physical examination tests of the hip. Journal: BMC Musculoskeletal Disorders Authors: Labib A. Rahman1; Sam Adie1,2,3 ; Justine M. Naylor 1,2,3; Rajat Mittal1,2,3; Sarah So1; Ian A. Harris1,2,3 1 South West Sydney Clinical School, University of New South Wales, 2Orthopaedic Department, Liverpool Hospital, 3Whitlam Orthopaedic Research Centre Study Test Pathology Reference Standard Adams et al. Patellar-Pubic Traumatic 1997 [1] Percussion Fracture Anwar et al. Trendelenburg Greater Radiography Radiography Sensitivity Specificity (95%CI) (95%CI) TP/ TN/ (TP+FN) (TN+FP) 0.79 0.95 0.65-0.83 0.84-0.99 15/19 21/22 0.80 0.71 PPV 0.94 NPV 0.84 +LR -LR (95%CI) (95%CI) 17.37 0.22 3.97- 0.17-0.42 98.43 0.53 0.89 2.74 0.28 1993 [2] Sign Trochanter (implied) Nonunion 0.54-0.94 0.60-0.77 8/10 17/24 0.91 0.82 083 – 0.96 0.72 – 0.88 51/56 36/44 0.73 0.77 0.51-0.87 0.59-0.89 8/11 10/13 1.36-4.02 0.08-0.76 5.01 0.11 2.92 – 0.04 – 8.20 0.28 3.15 0.35 1.24-7.84 0.15-0.83 following Cemented THA in patients with neglected Congenital Dislocation of the Hip (CDH) Bache et al. Bartford test Fractured neck Radiography of femur 1984 [3] Bird et al. Trendelenburg Partial or 2001 [4] Sign Complete MRI Gluteus Medius Tendon Tear 0.86 0.73 0.88 0.77 Bird et al. Pain on Resisted Partial or 2001 [4] Abduction Complete MRI 0.73 0.46 0.52-0.89 0.29-0.60 8/11 6/13 0.55 0.69 0.34-0.72 0.51-0.84 6/11 9/13 0.86 0.54 0.79-0.91 0.48-0.58 72/84 57/106 0.53 0.67 1.35 0.59 0.73-2.21 0.19-1.68 1.77 0.66 0.69-4.54 0.33-1.29 1.85 0.27 1.52-2.17 0.15-0.44 Gluteus Medius Tendon Tear Bird et al. Pain on Resisted Partial or 2001 [4] Adduction Complete MRI 0.60 0.64 Gluteus Medius Tendon Tear Birrell et al. Restriction in Mild-Moderate 2001 [5] One Plane from Symptomatic Either: (1) Osteoarthritis Radiography Passive Flexion ROM < 94o, (2) External Rotation ROM < 23o or (3) Internal Rotation 0.60 0.83 ROM < 23o. Measured in seated position with fluid plurimeter. Birrell et al. Restriction in Mild-Moderate 2001 [5] Two Planes from Symptomatic Either: (1) Osteoarthritis Radiography 0.56 0.77 0.48-0.63 0.71-0.83 47/84 82/106 Passive Flexion ROM < 94o, (2) External Rotation ROM < 23o or (3) Internal Rotation ROM < 23o. Measured in seated position 0.66 0.69 2.47 0.57 1.69-3.64 0.45-0.72 with fluid plurimeter. Birrell et al. Restriction in Mild-Moderate 2001 [5] Three Planes: (1) Symptomatic Passive Flexion Osteoarthritis Radiography 0.32 0.93 0.26-0.36 0.89-0.97 0.79 0.63 ROM < 94o, (2) 4.87 0.73 2.32- 0.66-0.83 10.57 External 27/84 99/106 0.57 0.85 Rotation ROM < 23o and (3) Internal Rotation ROM < 23o. Measured in seated position with fluid plurimeter. Garcia et al. Trendelenburg Abductor Sonography 0.50 0.88 3.86 0.50 2010 [6] Sign Avulsion Following 0.28-0.81 0.78-0.91 4/7 23/27 0.51 0.89 0.46 – 0.52 0.66 – 0.98 45/89 16/18 0.58 0.66 0.47–0.68 0.59–0.72 44/76 150/228 0.56 0.78 0.45–0.67 0.72–0.83 42/75 178/228 1.25 – 0.21-0.93 9.34 Primary THA Hananouchi et Anterior Anterosuperior al. 2012 [7] impingement test labral lesions Holla et al. Assisted active Early 2012 [8] hip flexion < symptomatic hip 114o as osteoarthritis MRI Radiography 0.96 0.36 0.27 0.82 4.55 0.56 1.35 – 0.49 – 26.64 0.82 1.69 0.64 1.30–2.20 0.48–0.85 2.55 0.56 1.86–3.51 0.43–0.73 measured with goniometer Holla et al. Assisted active Early 2012 [8] hip internal symptomatic hip rotation < 24o as osteoarthritis measured with goniometer Radiography 0.46 0.84 Hossain et al. Restricted Radiologically 2007 [9] Straight Leg Occult Hip Raise Fracture Hossain et al. Log Roll Test Radiologically 2007 [9] (Passive Occult Hip Rotation) Fracture Hossain et al. Pain on Axial Radiologically 2007 [9] Loading Occult Hip MRI MRI MRI 0.50 0.42 0.37-0.64 0.31-0.54 13/26 13/31 0.62 0.48 0.48-0.75 0.37-0.59 16/26 15/31 0.73 0.58 0.59-0.84 0.46-0.68 19/26 18/31 0.42 0.50 0.59 0.50 0.60 0.72 0.86 1.19 0.53-1.38 0.68-2.04 1.19 0.79 0.75-1.83 0.43-1.43 1.74 0.46 1.10-2.61 0.23-0.88 34.29 0.24 10.97 – 0.17-0.41 Fracture Khadilkar et Hip Abduction Sarcoglycan- Immunocyto- 0.76 0.98 al. 2001 [10]a Signb opathies in chemistry 0.61-0.83 0.94-0.99 16/21 88/90 patients with known muscular dystrophy 0.89 0.95 122.30 Narvani et al. Discomfort on Acetabular 2003 [11] Internal Labral Tears MRA 0.75 0.43 0.34-0.95 0.31-0.49 3/4 6/14 0.47 0.81 0.33-0.59 0.75-0.88 14/30 48/59 0.19 0.93 0.10-0.29 0.89-0.96 5/26 64/69 0.00 1.00 0.27 0.86 1.31 0.58 0.50-1.86 0.10-2.11 2.50 0.66 1.31-4.70 0.47-0.89 2.65 0.90 0.87-8.04 0.74-1.02 7.23 0.98 RotationFlexion-Axial Compression Manoeuvre Olsson et al. Trendelenburg Cemented 1981 [12] Sign Femoral Stem Radiography 0.56 0.75 Loosening PostTHA Olsson et al. Painful or Cemented 1981 [12] Impossible Femoral Stem Active Straight Loosening Post- Röder et al. Leg-Raise THA Pain on Axial Uncemented Radiography Radiography 0.50 0.00 0.71 0.99 2003 [13] Compression Acetabular Cup Loosening Post- 0.00-0.13 1.00-1.00 0/17 1685/ 1691 0.13 0.99 0.05-0.23 0.98-0.99 4/32 680/690 0.08 0.99 0.03-0.17 0.99-1.00 4/49 2365/ 2381 0.19 0.97 0.08-0.39 0.97-0.97 4/21 1639/ 1687 0.21 0.96 0.71 – 0.84 – 67.39 1.00 8.63 0.89 2.93- 0.78-0.97 THA Röder et al. Pain on Axial Uncemented 2003 [13] Compression Acetabular Cup Radiography 0.29 0.96 Loosening Post- 24.30 THA Pooled Data: Pain on Axial Uncemented Röder et al. Compression Acetabular Cup Radiography 0.20 0.98 Loosening Post- 2003 [13] 12.15 0.93 4.33 – 0.84 – 32.83 0.97 6.69 0.83 2.60- 0.63-0.95 THA Röder et al. Pain on Internal Uncemented 2003 [13] Rotation Acetabular Cup Radiography 0.08 0.99 Loosening Post- 14.91 THA Röder et al. Pain on Internal Uncemented Radiography 0.19 0.96 4.72 0.83 2003 [13] Rotation Acetabular Cup Loosening Post- 0.11-0.35 0.95-0.96 7/34 658/688 0.20 0.97 0.12 – 0.31 0.97 – 0.97 11/ 55 2297/ 2375 0.06 0.99 0.01-0.22 0.99-0.99 1/18 1677/ 1690 0.06 0.99 0.02-0.15 0.99-1.00 2/31 685/ 691 0.06 0.99 2.21-9.40 0.68-0.94 6.09 0.83 3.39 – 0.71 – 10.37 0.91 7.22 0.95 1.22- 0.78-1.00 THA Pooled Data: Pain on Internal Uncemented Röder et al. Rotation Acetabular Cup Radiography 0.12 0.07 Loosening Post- 2003 [13] THA Röder et al. Pain on External Uncemented 2003 [13] Rotation Acetabular Cup Radiography 0.07 0.99 Loosening Post- 37.83 THA Röder et al. Pain on External Uncemented 2003 [13] Rotation Acetabular Cup Radiography 0.25 0.96 Loosening Post- 7.43 0.94 1.74- 0.86-0.99 30.74 THA Pooled Data: Pain on External Uncemented Radiography 0.14 0.98 7.67 0.95 Röder et al. Rotation Acetabular Cup Loosening Post- 2003 [13] 0.02 – 0.14 0.99 – 0.99 3/ 49 2362/ 2381 0.00 0.99 0.00-0.26 0.99-1.00 0/8 746/ 752 0.02 1.00 0.00-0.04 0.99-1.00 1/61 441/443 0.01 0.99 0.00 – 0.06 0.99 – 1.00 1/ 69 1187/ 1195 1.00 0.95 2.45 – 0.86 – 22.97 0.99 6.44 0.95 0.64 – 0.63 – 54.06 77.34 3.63 0.99 0.48- 0.96-1.00 THA Röder et al. Pain on Axial Cemented 2003 [13] Compression Acetabular Cup Radiography 0.00 0.99 Loosening PostTHA Röder et al. Pain on Axial Cemented 2003 [13] Compression Acetabular Cup Radiography 0.33 0.88 Loosening Post- 27.51 THA Pooled Data: Pain on Axial Cemented Röder et al. Compression Acetabular Cup Radiography 0.11 0.95 Loosening Post- 2003 [13] 2.17 0.99 0.35 – 0.95 – 13.00 1.01 16.87 0.18 THA Röder et al. Pain on Internal Cemented Radiography 0.05 1.00 2003 [13] Rotation Acetabular Cup Loosening Post- 0.35-1.00 0.95-0.95 2/2 721/ 758 0.21 0.93 0.13-0.30 0.92-0.94 12/58 413/ 446 0.23 0.94 0.15 – 0.34 0.94 – 0.95 14/ 60 1134/ 1204 0.02 1.00 0.00-0.03 1.00-1.00 1/59 444/445 0.00 1.00 6.08 – 0.02 – 20.12 0.72 2.80 0.86 1.52-4.96 0.74-0.95 4.01 0.81 2.37 – 0.70 – 6.48 0.91 7.54 0.99 0.79- 0.97-1.00 THA Röder et al. Pain on Internal Cemented 2003 [13] Rotation Acetabular Cup Radiography 0.27 0.90 Loosening PostTHA Pooled Data: Pain on Internal Cemented Röder et al. Rotation Acetabular Cup Radiography 0.17 0.96 Loosening Post- 2003 [13] THA Röder et al. Pain on External Cemented 2003 [13] Rotation Acetabular Cup Radiography 0.50 0.88 Loosening Post- 72.05 THA Röder et al. Pain on External Cemented Radiography 0.00 0.99 16.73 0.95 2003 [13] Rotation Acetabular Cup Loosening Post- 0.00-0.16 1.00-1.00 0/8 750/ 752 0.02 1.00 0.00 – 0.04 1.00 – 1.00 1/67 1194 /1197 0.08 0.99 0.08-0.02 0.98-1.00 1/12 166/168 0.05 0.99 0.01-0.16 0.99-1.00 1/19 443/ 447 0.07 0.99 1.51 – 0.78 – 172.69 1.00 5.96 0.99 0.86 – 0.96 – 41.13 1.00 7.00 0.93 0.93- 0.81-1.00 THA Pooled Data: Pain on External Cemented Röder et al. Rotation Acetabular Cup Radiography 0.25 0.95 Loosening Post- 2003 [13] THA Röder et al. Pain on Axial Uncemented 2003 [13] Compression Femoral Stem Radiography 0.33 0.94 Loosening Post- 51.26 THA Röder et al. Pain on Axial Uncemented 2003 [13] Compression Femoral Stem Radiography 0.20 0.96 Loosening Post- 5.88 0.96 0.89- 0.84-1.00 37.05 THA Pooled Data: Pain on Axial Uncemented Radiography 0.25 0.96 6.61 0.95 Röder et al. Compression Femoral Stem Loosening Post- 2003 [13] 0.02 – 0.15 0.99 – 1.00 2/ 31 609 /615 0.18 0.96 0.08-0.35 0.95-0.97 4/22 425/ 444 0.33 0.93 0.15-0.57 0.92-0.95 4/12 157/ 168 0.24 0.95 0.13 – 0.38 0.95 – 0.96 8 /34 582 /612 0.00 0.99 1.55 – 0.86 – 27.35 0.99 4.25 0.86 1.57- 0.67-0.97 THA Röder et al. Pain on Internal Uncemented 2003 [13] Rotation Femoral Stem Radiography 0.17 0.96 Loosening Post- 10.35 THA Röder et al. Pain on Internal Uncemented 2003 [13] Rotation Femoral Stem Radiography 0.27 0.95 Loosening Post- 5.09 0.71 1.84- 0.45-0.93 11.80 THA Pooled Data: Pain on Internal Uncemented Röder et al. Rotation Femoral Stem Radiography 0.21 0.96 Loosening Post- 2003 [13] 4.80 0.80 2.35 – 0.65 – 9.14 0.92 2.60 0.98 THA Röder et al. Pain on External Uncemented Radiography 0.00 0.93 2003 [13] Rotation Femoral Stem Loosening Post- 0.00-0.11 0.99-1.00 0/12 166/ 168 0.05 () 0.99 () 0.01-0.18 0.99-0.99 1/19 441/ 447 0.03 0.99 0.01 – 0.12 0.99 – 0.99 1 /31 607 /615 0.02 0.99 0.00-0.04 0.99-0.99 2/136 898/ 910 0.04 1.00 0.23 – 0.85 – 27.49 1.01 3.92 0.96 0.62- 0.83-1.01 THA Röder et al. Pain on External Uncemented 2003 [13] Rotation Femoral Stem Radiography 0.14 0.96 Loosening Post- 22.91 THA Pooled Data: Pain on External Uncemented Röder et al. Rotation Femoral Stem Radiography 0.11 0.95 Loosening Post- 2003 [13] 2.48 0.98 0.40 – 0.89 – 14.42 1.01 1.12 1.00 0.28-4.37 0.97-1.01 17.34 0.97 THA Röder et al. Pain on Axial Cemented 2003 [13] Compression Femoral Stem Radiography 0.14 0.87 Loosening PostTHA Röder et al. Pain on Axial Cemented Radiography 0.43 0.96 2003 [13] Compression Femoral Stem Loosening Post- 0.01-0.06 1.00-1.00 3/83 1915/ 1919 0.02 0.99 0.01 – 0.04 0.99 – 1.00 5 /219 2813/ 2829 0.15 0.95 0.10-0.20 0.94-0.96 20/137 862/ 909 0.17 0.97 0.10-0.26 0.97-0.98 12/72 1876/ 1930 0.15 0.96 4.38- 0.94-0.99 68.47 THA Pooled Data: Pain on Axial Cemented Röder et al. Compression Femoral Stem Radiography 0.24 0.93 Loosening Post- 2003 [13] 4.04 0.98 1.54 – 0.96 – 10.48 1.00 2.82 0.90 1.72-4.56 0.84-0.96 5.96 0.86 3.31- 0.76-0.93 THA Röder et al. Pain on Internal Cemented 2003 [13] Rotation Femoral Stem Radiography 0.30 0.88 Loosening PostTHA Röder et al. Pain on Internal Cemented 2003 [13] Rotation Femoral Stem Radiography 0.21 0.97 Loosening Post- 10.34 THA Pooled Data: Pain on Internal Cemented Radiography 0.24 0.94 4.30 0.88 Röder et al. Rotation Femoral Stem Loosening Post- 2003 [13] 0.11 – 0.20 0.96 – 0.97 32/ 209 2738 /2839 0.02 0.99 0.00-0.03 0.99-1.00 2/137 903/ 909 0.06 1.00 0.03-0.09 1.00-1.00 5/85 1913/ 1917 0.03 1.00 0.02 – 0.05 1.00 – 1.00 2.96 – 0.83 – 6.19 0.92 2.21 0.99 0.51-9.48 0.97-1.00 28.19 0.94 8.30- 0.92-0.98 THA Röder et al. Pain on External Cemented 2003 [13] Rotation Femoral Stem Radiography 0.25 0.87 Loosening PostTHA Röder et al. Pain on External Cemented 2003 [13] Rotation Femoral Stem Radiography 0.56 0.96 Loosening Post- 95.94 THA Pooled Data: Pain on External Cemented Röder et al. Rotation Femoral Stem Radiography 0.41 0.22 Loosening Post- 2003 [13] 8.91 0.97 3.53 – 0.95 – 22.43 0.99 3.07 0.95 THA Röder et al. Flexion ROM < Uncemented Radiography 0.07 0.98 0.12 0.96 2003 [13] 70o Acetabular Cup Loosening Röder et al. Flexion ROM < Uncemented 2003 [13] 70o Acetabular Cup Radiography 0.02-0.18 0.98-0.98 2/30 675/ 690 0.00 0.98 0.00-0.10 0.98-0.99 0/33 1641/ 1670 0.06 0.98 0.01-0.21 0.98-0.98 2/32 2316/2360 0.00 0.96 0.00-0.34 0.96-0.96 0/7 712/ 745 0.08 0.94 0.04-0.16 0.94-0.95 5/61 410/ 435 0.7911.05 0.00 0.98 Loosening Pooled Data: Flexion ROM < Uncemented Röder et al. 70o Acetabular Cup Radiography 0.04 0.99 Loosening 2003 [13] Röder et al. Flexion ROM < Cemented 2003 [13] 70o Acetabular Cup Radiography Flexion ROM < Cemented 2003 70o Acetabular Cup Radiography Loosening 0.83 1.00 0.09 – 0.90 – 7.41 1.02 3.25 0.96 0.55- 0.81-1.01 12.31 0.00 0.99 Loosening Röder et al. 0.83-1.01 0.17 0.88 1.39 0.98 0.14 – 0.64 – 9.43 1.04 1.43 0.97 0.57-3.41 0.88-1.03 Pooled Data: Flexion ROM < Cemented Röder et al. 70o Acetabular Cup Radiography 0.07 0.95 0.03-0.16 0.95-0.96 5/68 1122/1180 0.14 0.97 0.05-0.31 0.96-0.98 3/21 428/ 442 0.15 0.99 0.05-0.22 0.99-1.00 2/13 166/ 167 0.15 0.98 0.06-0.28 0.97-0.98 5/34 594/609 0.03 0.95 0.08 0.95 0.97 0.54-3.65 0.88-1.03 4.51 0.89 1.43- 0.71-0.98 Loosening 2003 [13] Röder et al. Flexion ROM < Uncemented 2003 [13] 70o Femoral Stem Radiography Loosening Röder et al. Flexion ROM < Uncemented 2003 [13] 70o Femoral Stem Radiography 0.18 0.96 12.90 0.67 0.94 Loosening Pooled Data: Flexion ROM < Uncemented Röder et al. 70o Femoral Stem Radiography Flexion ROM < Cemented Radiography 25.69 0.85 3.48- 0.78-0.96 193.36 0.25 0.95 Loosening 2003 [13] Röder et al. 1.50 5.97 0.87 1.95- 0.73-0.97 16.128 0.04 0.96 0.51 1.03 2003 [13] 70o Femoral Stem Loosening Röder et al. Flexion ROM < Cemented 2003 [13] 70o Femoral Stem Radiography 0.01-0.08 0.95-0.95 2/80 1819/ 1912 0.07 0.96 0.04-0.11 0.96-0.97 9/138 863/ 898 0.05 0.95 0.03-0.09 0.95-0.96 11/218 2682/2810 0.20 0.87 0.14-1.81 0.96-1.05 1.67 0.97 0.83-3.33 0.92-1.01 1.11 1.00 0.57-2.06 0.95-1.02 0.50 1.04 0.03 – 0.94 – 8.57 1.15 Loosening Pooled Data: Flexion ROM < Cemented Röder et al. 70o Femoral Stem Radiography 0.08 0.93 Loosening 2003 [13] Shin et al. Active Flexion Femoral Neck 6-week Follow 0.00 1.00 1996 [14] ROM < 113o. Stress Fracture up Radiography 0.00-0.00 1.00-1.00 Measured using (radiologically 0/13 6/6 Goniometer. occult but suggestive bone - 0.32 scintigraphy) Shin et al. Active Extension Femoral Neck 6-week Follow 0.69 0.67 1996 [14] ROM < 28o. Stress Fracture up Radiography 0.55-0.80 0.35-0.89 Measured using (radiologically 9/13 4/6 Goniometer. occult but 0.82 0.50 2.08 0.46 0.84-7.16 0.23-1.31 0.81 3.50 0.72 – 0.40 – 1.28 37.01 0.31 1.69 0.08-1.29 0.92-3.32 suggestive bone scintigraphy) Shin et al. Active Internal Femoral Neck 6-week Follow 0.77 0.00 1996 [14] Rotation ROM < Stress Fracture up Radiography 0.77-0.89 0.00-0.26 45o. Measured (radiologically 10/13 0/6 using occult but Goniometer. suggestive bone 0.63 0.00 scintigraphy) Shin et al. Active External Femoral Neck 6-week Follow 0.15 0.50 1996 [14] Rotation ROM < Stress Fracture up Radiography 0.06-0.28 0.29-0.78 45o. Measured (radiologically 2/13 3/6 0.40 0.21 using occult but Goniometer. suggestive bone scintigraphy) Shin et al. Active Femoral Neck 6-week Follow 0.62 0.33 1996 [14] Abduction ROM Stress Fracture up Radiography 0.51-0.76 0.11-0.64 < 48o. Measured (radiologically 8/13 2/6 using occult but Goniometer. suggestive bone 0.67 0.29 0.92 1.15 0.57-2.10 0.38-4.62 1.50 0.10 1.00 – 0.01 – 1.72 0.98 1.11 0.46 scintigraphy) Shin et al. Pain on Log Roll Femoral Neck 6-week Follow 1.00 0.33 1996 [14] Test Stress Fracture up Radiography 0.90-1.00 0.12-0.33 13/13 2/6 0.92 0.17 0.76 1.00 (radiologically occult but suggestive bone scintigraphy) Shin et al. Pain on Active Femoral Neck 6-week Follow 0.71 0.50 1996 [14] Straight Leg Stress Fracture Raise (radiologically up Radiography 0.86-0.99 0.03-0.30 12/13 1/6 0.43 0.88 0.28-0.56 0.82-0.94 9/21 45/51 0.52 0.80 0.36-0.67 0.74-0.87 11/21 41/51 0.33 0.94 0.20-0.42 0.89-0.98 7/21 48/51 0.89-1.41 0.05-4.26 3.64 0.65 1.52-8.68 0.47-0.89 2.67 0.59 1.34-5.02 0.38-0.88 5.67 0.71 1.76- 0.59-0.90 occult but suggestive bone scintigraphy) Sutlive et al. Lateral Pain on Symptomatic 2008 [15] Active Hip Osteoarthritis Radiography 0.60 0.79 Flexion. Patient Supine. Sutlive et al. Pain on Active Symptomatic 2008 [15] Hip Extension. Osteoarthritis Radiography 0.52 0.80 Patient Prone. Sutlive et al. Pain on Symptomatic 2008 [15] Abduction Osteoarthritis Radiography and/or Adduction. 0.70 0.77 19.05 Patient Supine. Sutlive et al. Passive Internal Symptomatic 2008 [15] Rotation </= 25o. Osteoarthritis Radiography 0.76 0.61 0.58-0.89 0.54-0.66 16/21 31/51 0.24 0.96 0.13-0.31 0.91-0.99 5/21 49/51 0.62 0.75 0.44-0.77 0.67-0.81 13/21 38/51 0.57 0.71 0.40-0.73 0.63-0.77 12/21 36/51 0.44 0.86 1.94 0.39 1.25-2.60 0.17-0.78 6.07 0.79 1.46- 0.70-0.96 Measured with inclinometer. Patient Prone. Sutlive et al. Squat Test Radiography Osteoarthritis 2008 [15] Sutlive et al. Symptomatic Scour Test Symptomatic Radiography Osteoarthritis 2008 [15] Sutlive et al. FABER/ Symptomatic 2008 [15] Patrick’s Test < Osteoarthritis Radiography 60o 0.71 0.75 26.32 0.50 0.44 0.83 0.80 2.43 0.51 1.36-3.97 0.29-0.83 1.94 0.61 1.08-3.18 0.35-0.95 Sutlive et al. 5-Part Clinical Symptomatic 2008 [15] Prediction Rule c Osteoarthritis Radiography 0.95 0.18 0.82-0.99 0.12-0.19 20/21 9/51 0.81 0.61 0.63-0.92 0.54-0.65 17/21 31/51 0.71 0.86 0.55-0.84 0.79-0.91 15/21 44/51 0.48 0.98 0.34-0.52 0.93-1.00 10/21 50/51 0.32 0.90 1.16 0.27 0.94-1.23 0.05-1.46 2.06 0.31 1.37-2.65 0.12-0.68 5.20 0.33 2.66-9.57 0.18-0.57 24.29 0.53 4.64- 0.49-0.71 (>1 Variable positive) Sutlive et al. 5-Part Clinical Symptomatic 2008 [15] Prediction Rule c Osteoarthritis Radiography 0.46 0.89 (>2 Variables Positive) Sutlive et al. 5-Part Clinical Symptomatic 2008 [15] Prediction Rule c Osteoarthritis Radiography 0.68 0.88 (>3 Variables Positive) Sutlive et al. 5-Part Clinical Symptomatic 2008 [15] Prediction Rule c Osteoarthritis Radiography (>4 Variables Positive) 0.91 0.82 145.01 Sutlive et al. 5-Part Clinical Symptomatic 2008 [15] Prediction Rule c Osteoarthritis Radiography 0.14 0.98 0.06-0.18 0.95-1.00 3/21 50/51 0.96 0.86 0.94-0.97 0.74-0.93 245/ 255 30/35 0.75 0.74 (All 5 Variables 7.29 0.87 1.09- 0.82-1.00 50.33 Positive) Tiru et al. Patellar-Pubic Traumatic Repeat 2002 [16] Percussion Testd Fracture Radiography, (Radiologically Bone Occult) Scintigraphy, 0.98 0.75 6.73 0.05 3.61- 0.03-0.08 14.00 MRI or CT Table Legend: Positive Predictive Value (PPV), Negative Predictive Value (NPV), Positive Likelihood Ratio (+LR), Negative Likelihood Ratio (-LR), 95% Confidence Interval (95%CI), True Positives (TP), False Positives (FP), True Negatives (TN), False Negatives (FN), Range of Motion (ROM). All values rounded to 2 decimal places. When one of the cells of the 2x2 contingency table contained the value ‘zero’, we added 0.5 to each cell in order to calculate likelihood ratio values and their confidence intervals. a 10 healthy controls that tested negative with the index test were removed from our calculations Description of the Hip Abduction Sign in study by Khadilkar and Singh [10]: “Patients were asked to rise from the ground while they were observed from the front. After the initial efforts to get off the ground, as they began to climb up on their thighs, abduction of hip joints and thighs was noted. The test was considered positive when the angle subtended by both knees was more than 90o (that is, 45o on each side of the midline)” b c Clinical Prediction Rule consisted of 5 variables: (1) self-reported squatting as an aggravating factor, (2) scour test with adduction causing groin or lateral pain, (3) active hip flexion causing late pain, (4) active hip extension causing hip pain, and (5) passive hip internal rotation less than or equal to 25o. Description of the Patellar Pubic Percussion test in the study by Tiru et al. [16]: “The test was performed by percussing the patella and simultaneously auscultating with the bell of the stethoscope over the pubic symphysis. The percussion note was then compared over the contralateral side in a similar fashion. A positive test was one that resulted in diminished percussion note on the side of pain felt and a negative test was defined as one in which no difference in percussion note was obtained.” d References: 1. Adams SL, Yarnold PR: Clinical use of the patellar-pubic percussion sign in hip trauma. The American journal of emergency medicine 1997, 15:173-175. 2. Anwar MM, Sugano N, Masuhara K, Kadowaki T, Takaoka K, Ono K: Total hip arthroplasty in the neglected congenital dislocation of the hip. A five- to 14-year follow-up study. Clinical orthopaedics and related research 1993:127-134. 3. Bache JB, Cross AB: The Barford test. A useful diagnostic sign in fractures of the femoral neck. The Practitioner 1984, 228:305308. 4. Bird PA, Oakley SP, Shnier R, Kirkham BW: Prospective evaluation of magnetic resonance imaging and physical examination findings in patients with greater trochanteric pain syndrome. Arthritis and rheumatism 2001, 44:2138-2145. 5. Birrell F, Croft P, Cooper C, Hosie G, Macfarlane G, Silman A: Predicting radiographic hip osteoarthritis from range of movement. Rheumatology (Oxford, England) 2001, 40:506-512. 6. Garcia FL, Picado CH, Nogueira-Barbosa MH: Sonographic evaluation of the abductor mechanism after total hip arthroplasty. Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine 2010, 29:465-471. 7. Hananouchi T, Yasui Y, Yamamoto K, Toritsuka Y, Ohzono K: Anterior impingement test for labral lesions has high positive predictive value. Clin Orthop 2012, 470:3524-3529. 8. Holla JF, van der Leeden M, Roorda LD, Bierma-Zeinstra SM, Damen J, Dekker J, Steultjens MP: Diagnostic accuracy of range of motion measurements in early symptomatic hip and/or knee osteoarthritis. Arthritis Care Res (Hoboken) 2012, 64:59-65. 9. Hossain M, Barwick C, Sinha AK, Andrew JG: Is magnetic resonance imaging (MRI) necessary to exclude occult hip fracture? 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Shin AY, Morin WD, Gorman JD, Jones SB, Lapinsky AS: The superiority of magnetic resonance imaging in differentiating the cause of hip pain in endurance athletes. The American journal of sports medicine 1996, 24:168-176. 15. Sutlive TG, Lopez HP, Schnitker DE, Yawn SE, Halle RJ, Mansfield LT, Boyles RE, Childs JD: Development of a clinical prediction rule for diagnosing hip osteoarthritis in individuals with unilateral hip pain. The Journal of orthopaedic and sports physical therapy 2008, 38:542-550. 16. Tiru M, Goh SH, Low BY: Use of percussion as a screening tool in the diagnosis of occult hip fractures. Singapore medical journal 2002, 43:467-469.