Kin 310 Exercise/Work Physiology • Office hours - HC 2910 (lab) • F 10:30-11:20 – or by appointment (ryand@sfu.ca) • class email list – announcements, questions and responses – inform me of a preferred email account • class notes will be posted on the web site in power point each week – can be printed up to six per page • lecture schedule along with reading assignment on web site • www.sfu.ca/~ryand/kin310.htm 1 Energy for Exercise and Work Brooks p1-10; ch 4 • • Astrand ch. 17 p 503-540 • Mcardle, Katch and Katch Appendix D • Outline • • • • Introduction to Exercise Physiology Course overview Energy, work and power Calorimetry and the estimation of metabolic rate • Assessment of workload – Relative VO2, HR, Hormonal response • Energy expenditure over workday – Energy systems, work rest ratio 2 Exercise Physiology • Physiological responses to exercise depend on – Intensity, Duration, Frequency, Environmental circumstances, Diet, Health, Physiological status • Exercise requires the conversion of chemical into mechanical energy • Principles of bioenergetics control and limit performance • Acquisition and utilization of energy and the role of organ systems in supporting these processes will be discussed • Understanding short (acute) and long term (chronic) effects of exercise on the human machine is important in exercise science and health 3 Rate Limiting Factor • What limits performances? • Proper analysis of a sport or work situation is important to identify; – Pathways and metabolic sequences that are used – The factors which turn the rate of these pathways up or down – The steps that are limiting or slow • All of this is required to understanding function, pathophysiology (disease) and to concentrate efforts when training to improve performance • Eg. VO2 fig 1-5 • Limited by cardiovascular system • Widely used criterion of physical fitness 4 Performance • Stress and Response • With appropriate stimuli, physiological systems respond with increased functional capacity (training) • Overload but not overtrain • Seyle - General Adaptation Syndrome (GAS) – Alarm Reaction (shock) – Resistance Development (adaptation) – Exhaustion (staleness) • Principles of Fitness – – – – Overload Specificity Reversibility Individuality 5 • • • • • • • • • • Course Overview Discussion of the physiological basis of exercise and work Evaluating Energy and Workload Cardiovascular and respiratory compensations and capacities – Limitations and adaptations to training Cellular bioenergetics – Providing ATP to meet demand and recovery Fatigue - inability to sustain activity level – description of fatigue in the CNS, the neuromuscular junction and the muscle cell Molecular level adaptation – activity changes the cellular environment stimulating adaptation to better meet demand Work place / sport analysis and assessment of worker /athlete capacity Strength evaluation variables Ageing - change in physiological capacities impacts of disease and activity level Exercise and the Environment – Heat and barometric pressure can create additional demands on physiological systems 6 Energy • Energy - capacity or ability to perform work - joules, calories • Work - application of a force through a distance - joules, calories, Kg*m • Biological work - transport, mechanical and chemical work • Power - amount work performed over a specific time (workrate) - Joules/s; kg*m *min-1 • Transformation of energy - forms of energy can be converted from one form to another – chemical energy in food is transformed into mechanical energy of movement or other biological work – Biological energy cycle 7 Metabolism • Metabolism - the total of processes occurring ina living organism – Because heat is produced by these processes, the ‘metabolic rate’ can be measured by the rate of heat production • Ultimately, all metabolic processes depend on biological oxidation • Measuring O2 consumption is a good estimate of heat production, or metabolic rate • Energy Transduction – Photosynthesis – cell respiration (*not ventilation*) – cell work 8 Calorimetry • Calorie - heat energy required to raise one gram of water one degree Celcius • Calorimetry - procedure to measure metabolic rate – Direct Calorimetry - measurement of heat - very difficult – Indirect Calorimetry - measurement of Oxygen use - valid and reliable • Fig 4-8 Atwater and Rosa – Determined heat production, oxygen consumption and carbon dioxide production simultaneously – Established relationship between direct and indirect methods • Bomb calorimeter - energy value of food when ignited - fig 4-9 • Appendix D - Mcardle, Katch and Katch (on resreves) 9 Respiratory Quotient • Table 4.1 - energy per unit oxygen different - carbohydrates 6.4 % higher • Respiratory Quotient - Ratio of CO2 produced to O2 consumed • Value obtained gives an indication of the type of fuel being used in muscle – Pure Glucose RQ = 1.00 – Pure Fat RQ = .70 – Mixed fuel will provide intermediate value depending on mix • Fig 4.10 marathon RQ values • R value - an estimate of RQ that is measured at the mouth – Must consider non-metabolic sources of CO2 - Fig 4-14 10 Measurement of Metabolic Response • Evaluation provides info about absolute and relative intensity of exercise bout (fig 10.1a) – – – – absolute VO2 (L/min or ml/Kg/min) % of VO2 max % of HR max multiples of Metabolic Rate (MET’s) • 1kcal/Kg/hour at rest; 3.5mlO2/kg/min • determination of metabolic response allows estimation of – – – – Total energy cost Nutritional requirements Efficiency calculations Estimation of workload indicates metabolic system utilization, and the potential for fatigue 11 Work Load Assessment • Assessment of work load in relation to work capacity – variability in capacity – variability in response • expression of workload by absolute VO2 alone is almost meaningless • Need work load as % of individual max • Assessment requires the determination of ; – individual VO2 max – VO2 requirement of imposed load – assessment of muscle groups being utilized, and the % of their maximum strength -to determine fatigue onset 12 Assessment • Maximal aerobic power – direct - VO2 max test – estimation - predictive tests • Assessment of Workload – measure O2 uptake during work • Fig 17-2 O2 uptake vs bike/work – portable devices, rapid analysis of VCO2 and VO2 - large data base – field studies - collect expired air • Douglas bag – or - use flow meter to determine volume of air, and take samples of air for content analysis • Fig 17-3 commercial fisherman – subjects often affected - test atypical – Eg. Breathing through mouth not nose 13 Indirect assessment • Recall linear relationships between HR and VO2, VO2 and work rate – HR may be used to estimate workload on individual basis – same muscle groups environmental temperature, and emotional stress • Continuously recorded HR – provides general picture of overall activity level during entire day – along with time activity studies collected by observers – possible to separate different activities with respect to HR – Fig 17-5 - fisherman 14 Comparison studies • Fig 17-6 - strong day - day consistency • Computer analysis of HR data gives; – mean values, peak values, distribution and HR variability • Fig 17-8 comparison of direct vs indirect measurement +/- 15 % • HR is good estimate of workload when work uses large muscle groups • Fig 17-9 arm vs leg work – HR is higher in arm work than leg work for the same work load. • O2 uptake for work load must be expressed as % max of individual – indicates relative degree of exertion • HR reserve (HR max - HR rest) – Circulatory strain is best expressed as a percentage of an individuals HR reserve 15 Stress of Work • The total stress imposed on the organism by a given work situation (physical or psychological) is generally reflected by nervous and hormonal stimulation – Proportional to the degree of stress • Nervous Response • Inc sympathetic tone - inc HR – influence linear relationship – Eg HR vs workload • Hormonal response – total stress reflected by sympathetic response – Measure ep and/or nor ep with urinary excretion or blood samples • Fig 17-16, 17-17 - Catecholamines - inc with standing, cold and emotion – Also inc with duration and severity of muscular exertion 16 Energy Expenditure • Need to establish practical limits for physical work loads • Type of work and work/rest cycles are important • Large individual differences in physical work capacity – 30 - 40% VO2 max for 8 hour day – 40 % of max strength in repetitive muscular work; • rest:work ratio of ; 2:1 • physiological and psychological responses influenced by – – – – – – individual max aerobic power size of muscle being engaged working position Static or dynamic work intermittent vs continuous activity environmental conditions 17 Daily Energy Expenditure • Important for – calculation of energy needs – determine physical activity of groups – role of physical activity in health • Methodology – 24 hr recorded HR – time activity data – assessment of daily energy intake to maintain body weight – all fairly accurate +/- 15% • show large individual variability – 1300-5000 kcal /day • Table 17-1, 17-2 18 Energy expenditure • O2 uptake and HR - Table 17.1 • Important for ; – Calculation of energy needs – Determine physical activity of groups – Role of physical activity in health • Methodology All fairly accurate +/- 15% – 24 hr recorded HR ; Time activity data (video analysis) – Assessment of daily energy intake to maintain body weight • Wide individual variability in energy output - Table 17-1,2 – – – – Occupation Leisure activity / Physical activity Environmental temp Daily rate 1300 - 5000 kcal • Reg active male 2900 kcal/day • Reg active female 2100 kcal/day 19 Energy Expenditures • • • • • • • • • Work expenditures Most light work < 5 kcal /min Some physical jobs 7.5 - 10.5 kcal/min Permissible limits for daily work 20002500 kcal Limits are difficult due to individual differences in work capacity or fitness Individuals will usually self regulate the rest pauses Peak load is more important than mean energy expenditure You can attain a higher 8 hour energy expenditure if the work is consistent and does not have peak loads Basal Metabolic rate (BMR) - rate of energy metabolism in a resting individual 14-18 hours after eating 20 Energy Expenditure • Recreational activities • McArdle, Katch and Katch – Appendix C (on reserves) • Different activities have different energy expenditures – – – – – Cycling race Golf Skiing uphill fast Swimming -fast Running 5:30 mile 13 kcal/min 6 kcal/min 21 kcal/min 13 kcal/min 22 kcal/min • Individuals do activities at different intensities • Must take body weight into account 21