Essential Food Elements By Dr Hamda Qotba, B.Med.Sc, M.D, ABCM 2004 Dr. Hamda Qotba 1 Objectives 1) Introduction of important terminology 2) To know the function, source, structure of carbohydrates, proteins, and fat 3) Side effects of excess and insufficient intake of EFE 2004 Dr. Hamda Qotba 2 Terminology you have to know Nutrition: Process by which living organism receives material and uses them to promote it’s vital activities Nutrient: Any substance which is digested and absorbed to promote body function 2004 Dr. Hamda Qotba 3 Diet: Selection of food which is normally eaten by person or population Food: Substance when eaten , digested, absorbed provide at least one nutrient 2004 Dr. Hamda Qotba 4 Balanced diet : Diet that provide adequate amount of all nutrients Malnutrition: Caused by incorrect amount of nutrient intake Nutritional status: Health status that produced by balanced between requirements and intake 2004 Dr. Hamda Qotba 5 Nutritional assessment: Measurement of nutritional status by anthropometrics , biochemical data, dietary history Dietitian: Persons who applies science of nutrition to people in health and disease 2004 Dr. Hamda Qotba 6 Metabolism : Changes taking place in the body as result of body activity Anabolism: Complex molecules are synthesized from simpler ones Catabolism: Complex molecules are broken to simpler ones 2004 Dr. Hamda Qotba 7 Carbohydrates • Starch , sugar • Broken in the body to produce heat and energy • Oxidation of carbohydrate in the body produce CO2 and H2O • 1g ---- 16 kj (4kcal) 2004 Dr. Hamda Qotba 8 Structure • Monosaccharides: Glucose , fructose and galactose • Disaccharides: Sucrose , lactose and maltose • Polysaccharides: Amylose: straight chain of 70-350 glucose Amylopectin: branched chain of 100000 glucose 2004 Dr. Hamda Qotba 9 Sources of carbohydrates • • • • • • • • • 2004 Glucose ------ fruits fructose ------ honey sucrose ------ beet, cane lactose ------- milk Galactose ---- digestion of lactose maltose ------ sprouting grains starch ------ grains, unripe ft+veg. Glycogen---- liver, muscles Cellulose ------ cereals, veg., cell wall as fiber Dr. Hamda Qotba 10 Properties & uses • Sweetness differs fructose lactose • Glucose --- added for food when high energy required • Fructose --- sweetener in diabetes • Sucrose -- sweetener & preservative • Glucose syrup ---- jam 2004 Dr. Hamda Qotba 11 Digestion & Absorption • Starch pancreatic amylase maltotriose • Disaccharidases sucrose, maltose, lactose monosaccharide carbohydrate are absorbed in the single form • Absorbed by intestinal villi then travel by blood stream to the liver through the portal vein 2004 Dr. Hamda Qotba 12 Utilization 1. Used as fuel to produce energy for cell activity 2. Glycogen (glucose, galactose, fructose) is synthesized in liver and muscle and it’s used for muscular work 3. Converted into fat when liver and muscle are full with glycogen 2004 Dr. Hamda Qotba 13 Blood sugar level & Hormonal control • 65-180 mg/dl • Insulin β pancreatic cell assessing passage of glucose to cell • Adrenaline adrenal medulla glucose from the break down of glycogen in liver 2004 Dr. Hamda Qotba 14 • Glucagon pancreatic cell glucose from the break down of glycogen in liver • Growth hormone pituitary gland antagonize insulin 2004 Dr. Hamda Qotba 15 Intake • Traditional food consists mainly of carbohydrate like rice, wheat, corn, honey, jam, fruits and veg. • Excess intake obesity • lack intake ketosis • lack intake depletion of body tissue 2004 Dr. Hamda Qotba 16 Fat • • • • • • Carbon, Hydrogen, and Oxygen Glycerol + 3 fatty acid triglyceride Fatty acid e.g stearic, palmitic, oleic Saturated = single bond, stable Unsaturated = double bond, less stable Bond converted from double Unsaturated to single Saturated=hydrogenation 2004 Dr. Hamda Qotba 17 Hydrogenation • Change chemical and physical ->harder, raise melting point • Saturated= single bond (palmitic, stearic[lard] ) • Monosaturated= 1double bond (oleic[olive]) • Polyunsaturated= > 1double bond (linoleic[corn]) More hydrogen is introduced chemically 2004 Dr. Hamda Qotba 18 Rancidity & Solubility • In dairy product is due to liberation of free fatty acid as a result of hydrolysis of triglyceride by bacteria. • Non dairy product exposure to O2 cause oxidation • Emulsion: suspension of minute particle 2004 Dr. Hamda Qotba 19 Sources • Animal high in cholesterol (fat, butter, egg, milk) • Vegetable plant sterols that are poorly absorbed by man, not cholesterol (olive , cotton, corn) 2004 Dr. Hamda Qotba 20 Digestion • In the duodenum fat pancreatic lipase f.f.acid+monoglyceride • Enter mucosal cell to form triglycerides, combine with protein and cholesterol to form lipoprotein • The remainder are absorbed into portal circulation as fatty acid and glycerol 2004 Dr. Hamda Qotba 21 Function • Provide energy 37kj -> 9kcal/g • Incorporation into body structure brain and nervous system • Protection cover vital organs • Insulation prevent heat loss from the body • Satiety • Fat soluble vitamins ADEK 2004 Dr. Hamda Qotba 22 Stores & intake • • • Under skin, around abdominal organs There’s no definite amount of fat is known to maintain health Food as fat source: 1. High fat sources= >10% 2. Moderate fat sources= 3-10% 3. Poor fat sources = <2% 2004 Dr. Hamda Qotba 23 Essential fatty acid • They are polyunsaturated fatty acid needed for the body (linoliec, linolenic, arachinodic) • Deficiency due to malabsorption or prolonged IV intake • Vit. E important in preserving there chemical structure 2004 Dr. Hamda Qotba 24 • Cholesterol synthesized in the liver, attach it self to lipoprotein to be able to transfer in the body LDL bad cholesterol (<160mg/ml) HDL good cholesterol (>40mg/ml) 2004 Dr. Hamda Qotba 25 • Phospholipid Fatty material, integral part of the body (brain, nervous system) Present in blood plasma • Lipoprotein Plasma protein in which fat combine with them to be in the soluble form in the plasma 2004 Dr. Hamda Qotba 26 Proteins • Principle constituent of the cell • Composed of amino acid • Animal synthesis protein from A.A but not vice versa • Plant synthesis A.A from CO2, H2O, Nitrogen • Protein is the only source of nitrogen in the body 2004 Dr. Hamda Qotba 27 • By shape fibrous, globular • Protein in food like: myosin meat Albumin, vitellin egg Casein milk gluten wheat 2004 Dr. Hamda Qotba 28 Essential Amino Acid • A.A that the body are unable to make or make in insufficient amount Histidine lysine methionine Valine leucine isoleucine Tryptophan phenylalanine threonine 2004 Dr. Hamda Qotba 29 • Biological value Protein food that contain all A.A in the proportion needed for man is said to be high biological value (egg, human milk) • Limiting A.A essential A.A that food lack wheat soya beans maize lysine methionine trypyophan • This problem can be overcome by eating food that contains needed A.A 2004 Dr. Hamda Qotba 30 Function • Replace protein loss (wear & tear ) • Produce new tissue (growth, pregnancy) • Manufacture o new protein (enzyme) • Source of energy 2004 Dr. Hamda Qotba 31 Nitrogen balance • 6g protein 1g nitrogen • To be in nitrogen balance intake=output • Normal lose 14g • +ve nitrogen balance intake >loss (growth) • -ve nitrogen balance intake < loss (burns) 2004 Dr. Hamda Qotba 32 Digestion, absorption & excretion • • • Stomach proteolytic enzyme large polypeptides Duodenum pancreatic enzyme peptides+A.A peptides+A.A enter the intestinal cell: 1. Build structural proteins 2. Converted to other A.A 3. Produce energy Excreted by kidney in the form of urea 2004 Dr. Hamda Qotba 33 Intake • • If Insufficient impair healing& increase infection Deficiency may arise as a result of: 1. 2. 3. 4. 2004 If energy requirement increase Burn , fracture, injuries Failure to utilize protein Excessive loss Dr. Hamda Qotba 34 Protein Energy Malnutrition (PEM) • Kwashiorkor lack of protein, other energy sources • Result in growth retardation, infection, slow recovery, • Signs edema, muscle wasting ,liver enlargement, change in pigmentation 2004 Dr. Hamda Qotba 35 Protein Energy Malnutrition (PEM) • Marasmus lack of energy and protein • Sings muscle wasting, loss of S.C fat, growth retardation Overcome by breast feeding, nutritional supplement, nutrition education and improve sanitation 2004 Dr. Hamda Qotba 36