Local Drug Use Trends 2011 & What We Can Do D. Scott Kelly MA,CAADC,CRPS Co-Founder & Executive Director Bay Area Substance Education Services, Inc. (BASES) 208 W Lincoln, Charlevoix, MI 49720 (231) 547-1144 www.BASESTeenCenter.org scott@basesteencenter.org Local Trends in 2011 After all this time… Alcohol still most widely used locally Marijuana is on the rise Tobacco is still a concern Opiates & prescription pills are on the rise Heroin and needle use on the rise A New Development on Teen Alcohol Use http://www.clickondetroit.com/video/29237120/index.html New and unusual… Called “designer” or “club” drugs 10-20 years ago, now called synthetics Synthetic cannabinoids – round two this year Synthetic stimulants Over the counters, herbals, strange and unusual concoctions Alcohol - 30 Day Use Trends for Charlevoix County Students 3 Marijuana-30 Day Use Trends for Charlevoix County Students 4 When Parents Say No When Parents Allow Some Use 45 40 35 30 25 20 15 10 5 0 Alc/Drug Consequence Drinking & Driving Illicit Drug Use Anti-Social Behavior A Major Reason People Take a Drug is they Like What It Does to Their Brains Stimulants COCAINE METHAMPHETAMINE CRACK Types of Stimulant Drugs Cocaine Products Cocaine Powder (Generally sniffed, injected, smoked on foil) “Crack” (smoked) Major areas of use: South America; USA (predominantly major urban centers, disproportionately impacts African American community); Increasing in Europe. Types of Stimulant Drugs Amphetamine Type Stimulants (ATS) Amphetamine Dexamphetamine Methylphenidate Methamphetamine “Speed” “Ice” “Crank” “Yaba” “Shabu” Methamphetamine vs. Cocaine Cocaine half-life: 1-2 hours Methamphetamine half-life: 8-12 hours Cocaine paranoia: 4 -8 hours following drug cessation Methamphetamine paranoia: 7-14 days Methamphetamine psychosis - May require medication/hospitalization and may not be reversible Neurotoxicity: Appears to be more profound with amphetamine-like substances Scope of the Methamphetamine Problem Worldwide According to surveys and estimates by WHO and UNODC, methamphetamine is the most widely used illicit drug in the world except for cannabis. World wide it is estimated there are over 26 million regular users of amphetamine/methamphetamine, as compared to approximately 16 million heroin users and 14 million cocaine users Natural Rewards Elevate Dopamine Levels 200 % of Basal DA Output NAc shell 150 100 Empty 50 Box Feeding SEX 200 150 100 15 10 5 0 0 0 60 120 Time (min) 180 ScrScr BasFemale 1 Present Sample 1 2 3 4 5 6 7 8 Number Scr Scr Female 2 Present 9 10 11 12 13 14 15 16 17 Mounts Intromissions Ejaculations Source: Di Chiara et al. Source: Fiorino and Phillips Copulation Frequency DA Concentration (% Baseline) FOOD Effects of Drugs on Dopamine Release ETHANOL 400 % of Basal Release Accumbens Dose (g/kg ip) 200 0.25 0.5 1 2.5 150 100 0 1 2 3 Time After Ethanol 250 NICOTINE 200 Accumbens Caudate 150 100 COCAINE Accumbens DA DOPAC HVA 300 200 100 0 4hr Time After Cocaine METHAMPHETAMINE 1500 % Basal Release 0 % of Basal Release % of Basal Release 250 Accumbens 1000 500 0 0 0 1 2 3 hr Time After Nicotine 0 1 2 3hr Time After Methamphetamine Source: Shoblock and Sullivan; Di Chiara and Imperato Prolonged Drug Use Changes the Brain In Fundamental and Long-Lasting Ways Decreased dopamine transporter binding in METH users resembles that in Parkinson’s Disease patients Control Methamphetamine PD Source: McCann U.D.. et al.,Journal of Neuroscience, 18, pp. 8417-8422, October 15, 1998. Because… Their Brains have been Re-Wired by Drug Use Partial Recovery of Brain Dopamine Transporters in Methamphetamine (METH) Abuser After Protracted Abstinence 3 0 ml/gm Normal Control METH Abuser (1 month detox) METH Abuser (24 months detox) Source: Volkow, ND et al., Journal of Neuroscience 21, 9414-9418, 2001. – 33 year old man, high on methamphetamine admitted to emergency room complaining of severe headache in Portland Oregon. – X-ray revealed 12, 2 inch nails (6 on each side) in his head, administered with aq nail gun. – The man at first claimed it was an accident, but he later admitted that it was a suicide attempt. The nails were removed, and the man survived without any serious permanent damage. – He was eventually transferred to psychiatric care; he stayed for almost one month under court order but then left against doctors’ orders MSNBC-TV Long-term effects of stimulants Strokes, seizures, and headaches Irritability, restlessness Depression, anxiety, irritability, anger Memory loss, confusion, attention problems Insomnia Paranoia, auditory hallucinations, panic reactions Suicidal ideation Sinus infection Loss of sense of smell, nosebleeds, chronic runny nose, hoarseness Dry mouth, burned lips Worn teeth (due to grinding during intoxication) Problems swallowing Chest pain, cough, respiratory failure Disturbances in heart rhythm and heart attack Gastrointestinal complications (abdominal pain and nausea) Loss of libido Malnourishment, weight loss, anorexia Weakness, fatigue Tremors Sweating Oily skin, complexion METH Use Leads to Severe Tooth Decay “METH Mouth” Source: The New York Times, June 11, 20 Methamphetamine Psychiatric Consequences Paranoid reactions Long term memory loss Depressive reactions Hallucinations Psychotic reactions Panic disorders Rapid addiction More on Synthetics… Spice & K2 More on Synthetics… Bath Salts More on Synthetics… Spice & K2 http://www.slideshare.net/Guedde/spicek2-synthetic-cannabinoids-6988186 Bath Salts http://www.slideshare.net/Guedde/mdpv-bath-salts-emerging-drug-trends Based on local ER reports… More and more psychotic features coming into the emergency rooms locally Believed to be a result of synthetics – cannabinoids and stimulants Locals are involved in making their own concoctions of these and there is no way of knowing what is in them… Michigan Economics… High levels of unemployment locally Unemployment benefits running out With the increases in drug use and more bizarre psychiatric responses from these chemicals, there is potential for increases in property crimes and violent crimes Need to TAKE ACTION NOW in a multitude of ways…