State Standard SB1B - Explain how enzymes act as catalysts. Chapter 6 Chemistry in Biology 6.2 Chemical Reactions Physical vs. Chemical A physical change alters the substance’s appearance but not its composition. There is no formation of a new substance. Physical reaction Chapter 6 Chemistry in Biology 6.2 Chemical Reactions Physical vs. Chemical Cont’d A chemical reaction is the process by which atoms or groups of atoms in substances are reorganized into different substances. Clues that a chemical reaction has taken place include the production of heat or light, and formation of a gas, liquid, or solid. Not reversible! Chemical reaction Chapter 6 Chemistry in Biology 6.2 Chemical Reactions Chemical Equations Chemical formulas describe the substances in the reaction and arrows indicate the process of change. Chemical equations have 2 sides: Reactants are the starting substances, on the left side of the arrow. Products are the substances formed during the reaction, on the right side of the arrow. Chapter 6 Chemistry in Biology 6.2 Chemical Reactions Chemical Equations Cont’d Example of a chemical equation: During cellular respiration, Glucose and oxygen react to form carbon dioxide and water. Practice your knowledge by labeling the parts of the equation above. Chapter 6 Chemistry in Biology 6.2 Chemical Reactions Energy of Reactions The activation energy is the minimum amount of energy needed for reactants to form products in a chemical reaction. Chapter 6 Chemistry in Biology 6.2 Chemical Reactions Enzymes A catalyst is a substance that lowers the activation energy needed to start a chemical reaction. It does not increase how much product is made – only how quickly it is made. Enzymes are proteins that act as biological catalysts. Chapter 6 Chemistry in Biology 6.2 Chemical Reactions Enzymes Cont’d All living things are driven by constant internal chemical reactions (metabolism). Enzymes help these reactions happen quickly enough for an organism to stay alive. Enzymes increase the rate (speed) of a reaction by lowering activation energy. Chapter 6 Chemistry in Biology 6.2 Chemical Reactions Enzymes Cont’d The reactants that bind to the enzyme are called substrates. The specific location where a substrate binds on an enzyme is called the active site. Chapter 6 Chemistry in Biology 6.2 Chemical Reactions Enzymes Cont’d The active site changes shape and forms the enzyme-substrate complex, which helps chemical bonds in the reactants to be broken and new bonds to form. This is called induced fit. Chapter 6 Chemistry in Biology 6.2 Chemical Reactions Enzymes Cont’d Enzyme activity is affected by factors such as pH, temperature, & other substances. Extreme pH & temperature can change the shape of the enzyme and render it useless. This is called denaturing. Chapter 6 Chemistry in Biology 6.2 Chemical Reactions Enzymes Cont’d Enzymes are named for the substrates that they react with… Enzyme names end with the suffix “-ase”. Examples: Sucrase breakes down the sugar sucrose Lactase breaks down the sugar lactose Protease breaks down protein molecules Chapter 6 Chemistry in Biology 6.2 Chemical Reactions Enzymes Cont’d Enzyme action is often compared to the action of locks & keys… …because each enzyme is shaped to fit together with a specific substrate and they are reusable. Chapter 6 Chemistry in Biology Chapter 6 Chemistry in Biology Chapter Diagnostic Questions Identify the proteins that speed up the rate of chemical reactions. A. substrates B. enzymes C. ions D. reactants Chapter 6 Chemistry in Biology 6.2 Formative Questions Which is a chemical reaction? A. a match burning B. salt dissolving C. water boiling D. gasoline evaporating Chapter 6 Chemistry in Biology 6.2 Formative Questions How does an enzyme increase the rate of a chemical reaction? A. It acts as a reactant. B. It reduces the amount of heat produced. C. It increases the amount of product. D. It lowers the activation energy. Chapter 6 Chemistry in Biology 6.2 Formative Questions What occurs at the active site in the enzyme substrate complex? Chapter 6 Chemistry in Biology 6.2 Formative Questions A. An exothermic chemical reaction takes place. B. Chemical bonds are broken and new bonds are formed. C. The enzyme gets used up in the reaction. D. The substrates provide energy for the enzyme. Chapter 6 Chemistry in Biology 6.4 Formative Questions What type of biological molecule is an enzyme? A. hormone B. nucleic acid C. protein D. steroid Chapter 6 Chemistry in Biology Chapter Assessment Questions Look at the following figure. Determine what the upward curve represents. A. activation energy B. reactants C. products D. enzymes ?