Name: ____________________________________________________ Date: __________________ Block: _______ Online Karyotype Simulation Directions: 1. Go to: http://www.biology.arizona.edu/human_bio/activities/karyotyping/karyotyping.html 2. Read the Introduction and answer the pre‐lab questions below. 3. Click on “Patient Histories” to begin activity. 4. Click on “Complete Patient A’s Karyotype.” 5. Go through the activity. Write down the patient’s notation, which includes the total number of chromosomes, the sex chromosomes, and any missing or duplicated chromosomes. (Example, 47, XY, +18 is the notation for a man with an extra chromosome #18 which brings his total number of chromosomes to 47.) Finally, write down the Diagnosis for the patient. 6. Next, repeat step 5 again for Patient B. 7. Finally, Repeat step 5 again for Patient C. Pre­lab Questions: 1. To get a karyotype with visible chromosomes, a scientist must “block” cells in what stage of their life cycle? 2. To stain chromosomes, what dye is typically used? 3. When staining chromosomes, why do we get a banding pattern? 4. An analysis of the chromosomes is comparing what three things? 5. What are karyotypes used for? Data: Patient Notation Diagnosis A B C