a
expert reviews
in molecular medicine
Melanocytes in normal epidermis
(DOPA staining)
100 µm
b
Loss of melanocytes in an epidermis that is
affected by vitiligo (DOPA staining)
100 µm
Loss of melanocytes in epidermis
affected by vitiligo
Expert Reviews in Molecular Medicine
c 2001 Cambridge University Press
Loss of melanocytes in epidermis affected by vitiligo
http://www-ermm.cbcu.cam.ac.uk
Figure 1. Loss of melanocytes in epidermis
affected by vitiligo. (a) Melanocytes in a sheet of
normal epidermis shown by dihydroxyphenylalanine
(DOPA) staining, which detects the activity of the
melanogenic enzyme tyrosinase present in
melanocytes. (b) Appearance of an epidermal sheet
from a patient who has vitiligo, after staining with
DOPA, showing a much reduced melanocyte density.
Images courtesy of Dr D.J. Gawkrodger, Department
of Dermatology, Royal Hallamshire Hospital, Sheffield,
UK (fig001hks).
Accession information: (01)00337-4a.pdf (short code: fig001hks); 23 July 2001
ISSN 1462-3994 ©2001 Cambridge University Press
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