GENTAUR BVBA
Product Datasheet
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Product: Anti-Ectodysplasin A (Human), Affinity-Purified Polyclonal IgY Antibodies
Catalog Number: A22972
Lot Number: 04GA0168-040921
Quantity/Volume: 0.1mg/0.1 ml
Target Description: EDAR-associated death domain
isoform A; EDAR-associated death domain protein;
ectodysplasin A receptor associated adapter protein;
ectodysplasia A receptor associated death domain;
crinkled homolog
Target Information: The gene encoding this protein
was identified by its association with ectodermal
dysplasia, a genetic disorder characterized by
defective development of hair, teeth, and eccrine
sweat glands. The protein is a death domaincontaining protein, and is found to interact with EDAR,
a death domain receptor known to be required for the
development of hair, teeth and other ectodermal
derivatives. This protein and EDAR are coexpressed
in epithelial cells during the formation of hair follicles
and teeth. Through its interaction with EDAR, this
protein acts as an adaptor, and links the receptor to
downstream signaling pathways.
Related Reagents:
1. Goat anti-IgY Fc polyclonal antibodies
2. Rabbit anti-IgY polyclonal antibodies
3. Mouse anti-IgY Fc monoclonal antibody
Background References: Headon,D.J., Emmal,S.A.,
Ferguson,B.M., Tucker,A.S., Justice,M.J.,
Sharpe,P.T., Zonana,J. and Overbeek,P.A. TITLE
Gene defect in ectodermal dysplasia implicates a
death domain adapter in development JOURNAL
Nature 414 (6866), 913-916 (2001)
Western Blot Test: E coli-derived fusion protein as
test antigen. Affinity-purified IgY dilution: 1:2000, Goat
anti-IgY-HRP dilution: 1:1000. Colorimetric method for
signal development.
Protein GI Number: 22325375
Protein Accession #: NP_665860.1
Immunogen Information: aa 21-215
Species Reactivity: Human
Produced From: Chicken
Buffer: Phosphate-Buffered Saline. No preservatives
added
Storage Instruction: 4ºC for short term (weeks) and
-20ºC for long term. Avoid frequent freeze and thaw.
Important Notes: During shipment, small volumes of
product will occasionally become entrapped in the
seal of the product vial. For products with volumes of
200 µL or less, we recommend gently tapping the vial
on a hard surface or briefly centrifuging the vial in a
tabletop centrifuge to dislodge any liquid in the
container’s cap.
Recommended Application: Western blotting, tissue
or cell immunostaining. Recommended starting
dilution for Western blot analysis is 1:500, for tissue or
cell staining is 1:200. Optimal working dilutions must
be determined by the end user.
Recommended Control: Testing antigen control,
Pooled pre-immune background control.
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For research use only, not for diagnostic or therapeutic use.