Technical Assessment Form (TAF)

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Technical Assessment Form
Part A - To be completed by the applicant
1. Project Details
Title:
Proposed start Date:
Duration of the project
(months):
Proposed start date of
sequencing:
Grant scheme applying for:
Deadline for submission:
2. Proposed investigators
Role
Principal
Investigator
Co-Investigator
Name
Organisation
Division or Department
3. Principal Investigator’s Contact Details (full postal, telephone and email)
4. Summary of proposed work (Please limit to half a page and include genomics work pages
required, see http://www.tgac.ac.uk/contract-sequencing/ for further information.)
a. Project description
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Technical Assessment Form
b. Organism / Sample Details
Organism
Target size (e.g.
genome size,
transcriptome size,
amplicon length)
GC
Details of ploidy
Content and hetrozygosity/
repeat content, if
applicable
Further Information
(e.g. expected host
contamination)
c. Type of sequencing (please visit the TGAC site for information on the platforms currently
available: http://www.tgac.ac.uk/main-icons/technologies/sequencing-platforms/)
Please select from the following types of sequencing by completing the table below:
a. De novo
f. Epigenome/
b. Resequencing
g. Regulome
c. Transcriptomics
h. Target enrichment
d. Amplicon/
i. Other, please provide further details
e. Reduced Representation
Please indicate type
of sequencing (from
the above list)
Organism(s)
Number of
samples
Starting material
(e.g. genomic
DNA, total RNA)
Desired genomic/
transcriptomic coverage
and read metric
d. Bioinformatics Support (raw FASTQ data will be provided unless support is specified)
Please tick
Alignment (BAM / SAM output)
☐
‘First-Pass’ Assembly (FASTA output)
☐
Details of required data and
expected outcome
SNP and Variant calls – reference genome ☐
required (VCF output)
Gene expression analysis – reference
☐
genome accession no. required (RPKM or
FPKM output)
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Technical Assessment Form
Automated annotation
(GFF output)
Not required
☐
☐
Other, please provide further details:
5. Additional questions
a. Please tick this box to confirm that your samples will NOT present any biological hazards
requiring particular precautions to be taken
☐
b. How will the output received from TGAC be analysed and released? How will this activity be
resourced? Please provide details
c. Do you wish someone from your research centre to work with TGAC staff on a particular aspect
of analysis? If so, please provide details
TGAC follows BBSRC’s data sharing policy and expects data to be deposited in appropriate
databases in a timely manner. TGAC can assist you by depositing raw data (e.g. to the
Sequence Read Archive); analysed data sets can also be deposited as appropriate.
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Technical Assessment Form
Part B – Technical Assessment (To be completed by TGAC)
1. Date received by TGAC
2. Overall Assessment
Is the described plan of work appropriate for access to TGAC resources? Tick to confirm. ☐
3. Feasibility
Brief commentary on technical feasibility of the proposed work, including:
 appropriateness of scale, selected methodologies, expected timescales;
 identified risks;
 matching of work demands to TGAC capabilities and resources to deliver desired outputs.
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Technical Assessment Form
4. Costs of proposed work
Summary and breakdown of TGAC resource costs associated with the proposed programme of work.
Note to applicant:




The completed Technical Assessment Form must accompany research grant proposals
submitted to BBSRC, when these include use of TGAC resources. The total cost (including
VAT if applicable) should be entered into your Je-S proforma. Under Research Council
Facilities select TGAC from the list and enter the total cost in the Proposed Usage text box.
The total must be entered again under Other Directly Incurred Costs as TGAC Sequencing
Costs, so that the figure is included within your requested resources.
VAT will not be charged on collaborative research projects, but will be charged on
contractual research. VAT where applicable should be included in your funding request
from BBSRC. If you are unsure if VAT is applicable please contact your research office, or
finance team.
If TGAC has a Co-Investigator on the project, and a separate non-lead Je-S form, then the
costs below will be entered on the TGAC form only, but the TAF must be uploaded to the
lead Je-S component.
If your project is funded, please notify us (tgac.projects@tgac.ac.uk), we will schedule your
work and reclaim these costs by invoicing you.
Costs below do not include VAT.
Item
Unit of
Measure
Quantity
Cost
Total Cost
Section A
£
£
£
-
£
£
£
£
-
Section B
TOTAL
5. TGAC Project Contact:
Name:
Date:
This form, with Part A completed, should be submitted to TGAC at tgac.projects@tgac.ac.uk.
Please allow a minimum of 4 working weeks for consideration and return of the assessment
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Technical Assessment Form
to you.
On receipt of your research council reference number, please e-mail this to your TGAC
Project Manager (for our records).
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