Supplementary Table 3 (doc 118K)

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Supplementary Table 3. Genes of Study
Gene Symbol
CXCR4
Name of Gene
Chemokine receptor-4
Function/Role
Reference
uPAR
Urokinase plasminogen
activator receptor
cMET
Cell motility factor
receptor
AMFR
Autocrine motility factor
receptor
11-13
LOX
Lysyl oxidase
14, 15
Fas
Tumour necrosis factor
Receptor
VEGFC
Vascular endothelial
growth factor-C
1-3
4-7
Intra/Extravasation
Anti-Apoptotic
8-10
16, 17
18-21
Angiogenic factors
IL8
Interleukin -8
22-24
Hdm2
Transformed 3T3 double
minute 2
25, 26
OPN
Osteopontin
CA-9
Carbonic anhyrdase IX
Survival/Growth
factors
27-30
Biomarker for
hypoxia
31-33
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4.
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11.
Niizeki H, Kobayashi M, Horiuchi I, et al. Hypoxia enhances the expression of
autocrine motility factor and the motility of human pancreatic cancer cells. Br J
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13.
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14.
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15.
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17.
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Ueda M, Hung YC, Terai Y, et al. Vascular endothelial growth factor-C
expression and invasive phenotype in ovarian carcinomas. Clin Cancer Res
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19.
Van Trappen PO, Steele D, Lowe DG, et al. Expression of vascular endothelial
growth factor (VEGF)-C and VEGF-D, and their receptor VEGFR-3, during
different stages of cervical carcinogenesis. J Pathol 2003;201:544-554.
20.
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21.
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29.
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endogenous marker for hypoxic cells in cervical cancer. Cancer Res
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32.
Kim JY, Shin HJ, Kim TH, et al. Tumor-associated carbonic anhydrases are
linked to metastases in primary cervical cancer. J Cancer Res Clin Oncol
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33.
Vordermark D, Kaffer A, Riedl S, et al. Characterization of carbonic anhydrase
IX (CA IX) as an endogenous marker of chronic hypoxia in live human tumor
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