Questions on Peng, X.; Du, J.; Fan, J.; Wang, J.; Wu, Y.; Zhao, J.; Sun, S.; Xu, T. J
Amer. Chem. Soc., 2007, 129, 1500.
1) What is the reason for developing a sensor for Cd(II)?
2) How does a ligand such as ‘1’ in this paper sense Cd(II)? How, in general, do
ligands sense metal ions by fluorescence (the CHEF effect)?
3) Why is it important for the exciting and emitted radiation of this ligand and its
Cd(II) complex to be in the visible?
4) Why does ‘1’ have to have cell permeability?
5) Usually, Zn(II) is better at causing a ‘CHEF’ effect. What sort of factors can
cause a CHEF effect to be absent for Zn(II). (see C. Bazzicalupi, A. Benchini, A.
Bianchi, C. Giorgi, V. Fusi, B. Valtancoli, M. A. Bernado, and F. Pina, Inorg.
Chem., 38, 3806 (1999)).