Transcription Factor
Metabolic Protein
RNA polymerase I enhancer binding protein;
DNA binding protein which binds to genes
transcribed by both RNA polymerase I and
RNA polymerase II; required for termination
of RNA polymerase I transcription
Bifunctional enzyme of the 'de novo' purine
nucleotide biosynthetic pathway, contains
aminoimidazole ribotide synthetase and
glycinamide ribotide synthetase activities
Mybrelated transcription factor involved in
regulating basal and induced expression of
genes of the purine and histidine
biosynthesis pathways
serine hydroxymethyltransferase
Subunit of the hemeactivated,
glucoserepressed Hap2p/3p/4p/5p
CCAATbinding complex, a transcriptional
activator and global regulator of respiratory
gene expression; contains sequences
sufficient for both complex assembly and
DNA binding
Mitochondrial inner membrane ADP/ATP
translocator, exchanges cytosolic ADP for
mitochondrially synthesized ATP; expressed
under anaerobic conditions; similar to Pet9p
and Aac1p; has roles in maintenance of
viability and in respiration
Transcriptional activator involved in
regulation of genes of the lysine biosynthesis
pathway; requires 2aminoadipate
semialdehyde as coinducer
Putative SadenosylLhomocysteine hydrolase
with a probable role in
Sadenosylhomocysteine catabolism and/or
methionine degradation
Transcriptional activator of genes involved in ATPase, involved in resistance to heat and
glycolysis, functions and interacts with Gcr1p metal stress, active as a dimer; normally
localized to the cytosol, but appears to
localize to late endosomes under stress
conditions
Transcription factor of the forkhead family
that regulates the cell cycle and
pseudohyphal growth; also involved in
chromatin silencing at HML and HMR;
potential Cdc28p substrate
Glucoserepressible alcohol dehydrogenase
II, involved in the production of certain
carboxylate esters
Subunit of the hemeactivated,
glucoserepressed Hap2p/3p/4p/5p
CCAATbinding complex, a transcriptional
activator and global regulator of respiratory
gene expression; contains sequences
sufficient for both complex assembly and
DNA binding
biosynthesis of spermidine; putrescine
aminopropyltransferase (spermidine
synthase)
Subunit of the hemeactivated,
glucoserepressed Hap2p/3p/4p/5p
CCAATbinding complex, a transcriptional
activator and global regulator of respiratory
gene expression; contains sequences
sufficient for both complex assembly and
DNA binding
Constitutively expressed isoform of
DLglycerol3phosphatase; involved in glycerol
biosynthesis, induced in response to both
anaerobic and, along with the Hor2p/Gpp2p
isoform, osmotic stress
Subunit of the hemeactivated,
glucoserepressed Hap2p/3p/4p/5p
CCAATbinding complex, a transcriptional
activator and global regulator of respiratory
gene expression; contains sequences
sufficient for both complex assembly and
DNA binding
GTPcyclohydrolase I, catalyzes the first step
in the folic acid biosynthetic pathway
Transcription Factor
Metabolic Protein
Subunit of the hemeactivated,
glucoserepressed Hap2p/3p/4p/5p
CCAATbinding complex, a transcriptional
activator and global regulator of respiratory
gene expression; contains sequences
sufficient for both complex assembly and
DNA binding
Cystathionine betasynthase, catalyzes the
first committed step of transsulfuration in
cysteine biosynthesis
Protein involved in negative regulation of
transcription, exhibits regulated interactions
with both histones and SWISNF components,
has similarity to mammalian HMG1 proteins
Inosine monophosphate dehydrogenase,
catalyzes the first step of GMP biosynthesis,
expression is induced by mycophenolic acid
resulting in resistance to the drug, expression
is repressed by nutrient limitation
Protein involved in negative regulation of
transcription, exhibits regulated interactions
with both histones and SWISNF components,
has similarity to mammalian HMG1 proteins
6phosphogluconate dehydrogenase,
decarboxylating; converts
6phosphogluconate + NADP to
ribulose5phosphate + NADPH + CO2;
Phosphogluconate Dehydrogenase
(Decarboxylating)
Protein involved in negative regulation of
Cystathionine betasynthase, catalyzes the
transcription, exhibits regulated interactions
first committed step of transsulfuration in
with both histones and SWISNF components, cysteine biosynthesis
has similarity to mammalian HMG1 proteins
Subunit of the hemeactivated,
glucoserepressed Hap2p/3p/4p/5p
CCAATbinding complex, a transcriptional
activator and global regulator of respiratory
gene expression; contains sequences
sufficient for both complex assembly and
DNA binding
Putative SadenosylLhomocysteine hydrolase
with a probable role in
Sadenosylhomocysteine catabolism and/or
methionine degradation
Protein involved in negative regulation of
transcription, exhibits regulated interactions
with both histones and SWISNF components,
has similarity to mammalian HMG1 proteins
Putative SadenosylLhomocysteine hydrolase
with a probable role in
Sadenosylhomocysteine catabolism and/or
methionine degradation
Transcription factor that activates
transcription of genes expressed in G1 phase
and at the G1/M boundary; localization to the
nucleus occurs during G1 and appears to be
regulated by phosphorylation by Cdc28p
kinase
Long chain fatty acylCoA synthetase; accepts
a wider range of acyl chain lengths than
Faa1p, preferring C9:0C13:0; involved in the
activation of endogenous pools of fatty acids
Transcriptional activator related to Msn2p;
activated in stress conditions, which results in
translocation from the cytoplasm to the
nucleus; binds DNA at stress response
elements of responsive genes, inducing gene
expression
ATPase, involved in resistance to heat and
metal stress, active as a dimer; normally
localized to the cytosol, but appears to
localize to late endosomes under stress
conditions
Protein involved in negative regulation of
transcription, exhibits regulated interactions
with both histones and SWISNF components,
has similarity to mammalian HMG1 proteins
Mitochondrial inner membrane ADP/ATP
translocator, exchanges cytosolic ADP for
mitochondrially synthesized ATP; expressed
under anaerobic conditions; similar to Pet9p
and Aac1p; has roles in maintenance of
viability and in respiration
Basic leucine zipper (bZIP) transcription
factor
Glycogen synthase with similarity to Gsy2p,
the more highly expressed yeast homolog;
expression induced by glucose limitation,
nitrogen starvation, enviromental stress, and
entry into stationary phase
Transcription Factor
Metabolic Protein
Transcriptional activator involved in
alcohol dehydrogenase isoenzyme V
regulation of genes of the lysine biosynthesis
pathway; requires 2aminoadipate
semialdehyde as coinducer
RNA polymerase I enhancer binding protein;
DNA binding protein which binds to genes
transcribed by both RNA polymerase I and
RNA polymerase II; required for termination
of RNA polymerase I transcription
Bifunctional enzyme of the 'de novo' purine
nucleotide biosynthetic pathway, contains
aminoimidazole ribotide synthetase and
glycinamide ribotide synthetase activities
Mybrelated transcription factor involved in
regulating basal and induced expression of
genes of the purine and histidine
biosynthesis pathways
serine hydroxymethyltransferase
Subunit of the hemeactivated,
glucoserepressed Hap2p/3p/4p/5p
CCAATbinding complex, a transcriptional
activator and global regulator of respiratory
gene expression; contains sequences
sufficient for both complex assembly and
DNA binding
Mitochondrial inner membrane ADP/ATP
translocator, exchanges cytosolic ADP for
mitochondrially synthesized ATP; expressed
under anaerobic conditions; similar to Pet9p
and Aac1p; has roles in maintenance of
viability and in respiration
Transcriptional activator involved in
regulation of genes of the lysine biosynthesis
pathway; requires 2aminoadipate
semialdehyde as coinducer
Putative SadenosylLhomocysteine hydrolase
with a probable role in
Sadenosylhomocysteine catabolism and/or
methionine degradation
Transcriptional activator of genes involved in ATPase, involved in resistance to heat and
glycolysis, functions and interacts with Gcr1p metal stress, active as a dimer; normally
localized to the cytosol, but appears to
localize to late endosomes under stress
conditions
Transcription factor of the forkhead family
that regulates the cell cycle and
pseudohyphal growth; also involved in
chromatin silencing at HML and HMR;
potential Cdc28p substrate
Glucoserepressible alcohol dehydrogenase
II, involved in the production of certain
carboxylate esters
Subunit of the hemeactivated,
glucoserepressed Hap2p/3p/4p/5p
CCAATbinding complex, a transcriptional
activator and global regulator of respiratory
gene expression; contains sequences
sufficient for both complex assembly and
DNA binding
biosynthesis of spermidine; putrescine
aminopropyltransferase (spermidine
synthase)
Subunit of the hemeactivated,
glucoserepressed Hap2p/3p/4p/5p
CCAATbinding complex, a transcriptional
activator and global regulator of respiratory
gene expression; contains sequences
sufficient for both complex assembly and
DNA binding
Constitutively expressed isoform of
DLglycerol3phosphatase; involved in glycerol
biosynthesis, induced in response to both
anaerobic and, along with the Hor2p/Gpp2p
isoform, osmotic stress
Subunit of the hemeactivated,
glucoserepressed Hap2p/3p/4p/5p
CCAATbinding complex, a transcriptional
activator and global regulator of respiratory
gene expression; contains sequences
sufficient for both complex assembly and
DNA binding
GTPcyclohydrolase I, catalyzes the first step
in the folic acid biosynthetic pathway
Transcription Factor
Metabolic Protein
Subunit of the hemeactivated,
glucoserepressed Hap2p/3p/4p/5p
CCAATbinding complex, a transcriptional
activator and global regulator of respiratory
gene expression; contains sequences
sufficient for both complex assembly and
DNA binding
Cystathionine betasynthase, catalyzes the
first committed step of transsulfuration in
cysteine biosynthesis
Protein involved in negative regulation of
transcription, exhibits regulated interactions
with both histones and SWISNF components,
has similarity to mammalian HMG1 proteins
Inosine monophosphate dehydrogenase,
catalyzes the first step of GMP biosynthesis,
expression is induced by mycophenolic acid
resulting in resistance to the drug, expression
is repressed by nutrient limitation
Protein involved in negative regulation of
transcription, exhibits regulated interactions
with both histones and SWISNF components,
has similarity to mammalian HMG1 proteins
6phosphogluconate dehydrogenase,
decarboxylating; converts
6phosphogluconate + NADP to
ribulose5phosphate + NADPH + CO2;
Phosphogluconate Dehydrogenase
(Decarboxylating)
Protein involved in negative regulation of
Cystathionine betasynthase, catalyzes the
transcription, exhibits regulated interactions
first committed step of transsulfuration in
with both histones and SWISNF components, cysteine biosynthesis
has similarity to mammalian HMG1 proteins
Subunit of the hemeactivated,
glucoserepressed Hap2p/3p/4p/5p
CCAATbinding complex, a transcriptional
activator and global regulator of respiratory
gene expression; contains sequences
sufficient for both complex assembly and
DNA binding
Putative SadenosylLhomocysteine hydrolase
with a probable role in
Sadenosylhomocysteine catabolism and/or
methionine degradation
Protein involved in negative regulation of
transcription, exhibits regulated interactions
with both histones and SWISNF components,
has similarity to mammalian HMG1 proteins
Putative SadenosylLhomocysteine hydrolase
with a probable role in
Sadenosylhomocysteine catabolism and/or
methionine degradation
Transcription factor that activates
transcription of genes expressed in G1 phase
and at the G1/M boundary; localization to the
nucleus occurs during G1 and appears to be
regulated by phosphorylation by Cdc28p
kinase
Long chain fatty acylCoA synthetase; accepts
a wider range of acyl chain lengths than
Faa1p, preferring C9:0C13:0; involved in the
activation of endogenous pools of fatty acids
Transcriptional activator related to Msn2p;
activated in stress conditions, which results in
translocation from the cytoplasm to the
nucleus; binds DNA at stress response
elements of responsive genes, inducing gene
expression
ATPase, involved in resistance to heat and
metal stress, active as a dimer; normally
localized to the cytosol, but appears to
localize to late endosomes under stress
conditions
Protein involved in negative regulation of
transcription, exhibits regulated interactions
with both histones and SWISNF components,
has similarity to mammalian HMG1 proteins
Mitochondrial inner membrane ADP/ATP
translocator, exchanges cytosolic ADP for
mitochondrially synthesized ATP; expressed
under anaerobic conditions; similar to Pet9p
and Aac1p; has roles in maintenance of
viability and in respiration
Basic leucine zipper (bZIP) transcription
factor
Glycogen synthase with similarity to Gsy2p,
the more highly expressed yeast homolog;
expression induced by glucose limitation,
nitrogen starvation, enviromental stress, and
entry into stationary phase
Transcription Factor
Metabolic Protein
Transcriptional activator involved in
alcohol dehydrogenase isoenzyme V
regulation of genes of the lysine biosynthesis
pathway; requires 2aminoadipate
semialdehyde as coinducer