Thematic module 1. Basic concepts of pharmacy compounding

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THEMATIC PLAN OF PRACTICAL CLASSES
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7
8
Theme
V semester
MODULE 1. BASIC CONCEPTS OF PHARMACY COMPOUNDING.
POWDERS. LIQUID MEDICINAL FORMS
Thematic module 1. Basic concepts of pharmacy compounding. Powders
Pharmacy compounding as science. Purpose and task of the subject. Basic terms and concept of
pharmacy compounding. History of development of pharmacy compounding. Classification of medical
forms. Medical and auxiliary matters. Concept about doses. Containers and other materials which are
used in pharmacy practice.
State setting of norms of pharmacy compounding and basic normatively-technical documents.
Prescription, forms of prescription blanks, rules of its registration, structure. Sanitary and
pharmaceutical mode.
Dosage in pharmacy compounding (by mass, volume and drops). Structure and verification of tare and
hand scales. The features of dosage of medications by mass depending on their consistency.
Colloquium: “Pharmacy compounding as science. Purpose and task of the subject. Basic terms and
concept of pharmacy compounding. History of development of pharmacy compounding. Classification
of medical forms. Medical and auxiliary matters. Concept about doses. Containers and other materials
which are used in pharmacy practice. State setting of norms of pharmacy compounding and basic
normatively-technical documents. Prescription, forms of prescription blanks, rules of its registration,
structure. Sanitary and pharmaceutical mode.”
Compounding of simple and complex powders with the medicinal matters that differ by the prescribed
amount, mass and structure of particles.
Compounding of complex powders with the poisonous and drastic matters. Triturations.
Compounding of complex powders with volatile, dyeing, hard-grinded matters.
Compounding of complex powders with extracts, liquids and ready-to-cook mixtures. Estimation of
quality of powders.
Control of thematic module 1
Hours
2
2
2
2
2
2
2
2
Thematic module 2. Liquid non-sterile medicinal forms
9
10
11
General description and classification of liquid medical forms.
Solvents in technology of liquid medicines.
Compounding of water solutions of good-dissolved medicinal matters.
Special cases of water solutions compounding.
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2
2
12
Compounding of the concentrated solutions for the buret system. Calculations for concentration
correction.
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13
Compounding of liquid medical forms by mass-volume method by dissolution of dry medicinal matters
and using concentrated solutions. Estimation of quality of mixtures.
2
14
Drops for internal and external use.
2
15
Compounding of liquid medical forms by breeding of standard pharmakopoeian liquids.
2
16
17
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20
Colloquium: „Water solutions and their compounding. Concentrated solutions. Drops. Breeding of
alcohol and standard pharmakopoeian liquids”.
Compounding of alcohol, glycerin and oil solutions. Calculations for breeding of alcohol.
Colloquium: „ non-aqueous solutions and their compounding. Concentrated solutions. Drops.
Breeding of alcohol and standard pharmakopoeian liquids”.
Control of thematic module 2
Final module control 1
VI semester
MODULE 2. LIQUID MEDICINAL FORMS MODULE
Thematic module 3. Heterogeneous liquid medical forms
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2
2
2
2
1
2
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4
5
6
7
Solutions of high molecular medicines (HMM). Compounding of solutions of pepsin, gelatin, starch.
Estimation of quality of HMM solutions.
Colloid solutions. Compounding of protargol, collargol and ichthyol solutions.
Suspensions of the hydrophylic and hydrophobic matters. Stabilizing of suspensions. Estimation of
quality of suspensions.
Compounding of suspensions by dispersion and condensation methods.
Emulsions. Compounding of emulsions with the use of different emulgators. Adding medicinal matters
to emulsions. Estimation of quality.
Oil emulsions. Compounding of semin emulsions.
Control of thematic module 3
2
2
2
2
2
2
2
23
24
Thematic module 4. Water extractions
Infusions and decoctions. Description. Theoretical bases of extraction process. Apparatus and
estimation of quality. Compounding of water extractions from MPM, which contains alkaloids,
cardiac glycosides.
Compounding of water extractions from MPM which contains undrastic matters, essential oils,
tannic matters, antrahinones, saponines.
Compounding of water extractions from MPM which contains mucouses. Technology of water
extractions with the use of extracts-concentrates. Technology of complex medicines including
water extractions. Authors’ prescriptions. Estimation of quality, storage of water extractions.
Improvement of technology of infusions and decoctions.
Control of thematic module 4
Final module control
MODULE 3. SOFT AND ASEPTIC MEDICINAL FORMS.
EMBARRASSING PRESCRIPTIONS. PHARMACEUTIC INCOMPATIBILITIES
Thematic module 4. Ointments. Suppositories
Liniments. Compounding of homogeneous liniments. Estimation of quality.
Liniments. Compounding of suspensive, emulsive and combined liniments. Estimation of quality.
Ointments. Compounding of homogeneous ointments.
Compounding of suspensive and emulsive ointments.
Compounding of combined ointments. Estimation of quality.
Suppositories. Compounding of suppositories by hand rolling method. Adding of different
medicinal matters to suppositories.
Compounding of suppositories by fusion molding method. Adding of different medicinal matters
to suppositories. Estimation of quality of suppositories.
Pills. Compounding of pills. Estimation of quality.
Control of thematic module 5
Thematic module 6. Medicinal forms that should be compounded aseptically
Aseptics. Solutions for the injections. Solvents which are used for compounding of injection
solutions.
Compounding of solutions for injections without a stabilizer. Aseptic method of compounding.
Compounding of solutions for the injections with stabilizers. Stabilizing by acids and alkalis.
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Compounding of solutions for the injections with stabilizers. Stabilizing by antioxidants.
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27
Compounding of isotonic solutions.
Compounding of infusion solutions. Estimation of quality of solutions for injections.
Eye medicinal forms. Compounding of eye drops by dissolution of dry medicinal matters and
using concentrates.
Compounding of solutions for injections without a stabilizer. Aseptic method of compounding.
Medicinal forms with antibiotics. Medicinal forms for newborns. Determination. Description.
Requirements, their ground and realization. Estimation of quality.
Colloquium: „Medicinal forms that should be compounded aseptically”.
Control of thematic module 6
2
2
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28
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Embarrassing prescriptions. Physical, chemical, pharmacological incompatibilities in different
medicinal forms.
Final module control 3
2
2
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