BIO 265: Introduction to Immunology
Winter 2011
Monday 1:30 – 3:10 pm
(room 1706 in Walla Walla & room 0201 in Clarkston)
Instructor: Dr. Jeanine Kay-Shoemake
e-mail: jeanine.kay-shoemake@wwcc.edu
Office hours: M and W 10:30- 11:30, F 11:30 – 12:30; and by appointment
Office: 217D
Phone: (509) 524-4799
Course Code: 0252, 6030
Science Division
Type of Instruction: Lecture: 2 hours per week
Course Description
Tissues, cells and molecules of immune system, innate immunity and
complement, adaptive immunity, cellular and humoral immune responses,
cytokines, T-cell activation, the major histocompatibility complex, antibody
structure and function, immune system and cancer, autoimmunity,
hypersensitivity. Prerequisite: Grade of C or higher in BIO 230 or 211, or
concurrent enrollment in the WWCC Nursing Program.
Course Objectives
 Name and describe the principal organs, cells and molecules of the
immune system and their functions.
 Compare the innate immunity vs. adaptive immunity.
 Explain what the immune response is, specifically with respect to Humoral
immunity and Cellular immunity.
 Know the structure and function of the 5 different classes of
immunoglobulins.
 Explain how vaccinations work to create long-term host immunity.
 Know what the MHC is and its relationship to tissue compatibility.
 Predict the consequences of a deficiency in one particular component of
the immune system or a microbe evasion strategy in the immune
response.
Note students regarding disabilities: If you have a disability and need
accommodations, please see the instructor after class or contact Claudia Angus,
Coordinator of Disability Support Services at 527-4262 or 527-4543.
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Evaluation/Grading
Student understanding of the material will be evaluated using lecture exams and a
brief writing assignment.
Points possible
Exam 1
100
Exam 2
50
Exam 3
100
Exam 4
100
Total points possible
350 points
Your final grade will be calculated based on the percentage of the total points you
have earned out the total possible points applied to a standard grading scale, with
+/- system. Percentages will be rounded to the nearest 1/100th of a percentage
point for assignment of grades.
Grade
A
AB+
B
BC+
C
CD+
D
F
GPA
4.0
3.7
3.3
3.0
2.7
2.3
2.0
1.7
1.3
1.0
0.0
Percentage range
93.00
100 %
90.00
92.99 %
87.00
89.99 %
83.00
86.99 %
80.00
82.99 %
77.00
79.99 %
73.00
76.99 %
70.00
72.99 %
67.00
69.99 %
60.00
66.99 %
0
59.99 %
There will be NO extra-credit work given in this class.
Testing Policy: Lecture exams will be given on the dates indicated on the attached
schedule, although changes may occur. Exams will be given in the lecture
classroom, and the amount of time allowed to complete the exam is approximately
1 hour. If you are unable to attend the exam at the scheduled time, you must
contact me prior to exam time and provide a substantiated excuse. Make-up
exams will be taken at the Testing Lab during a time that is mutually agreed upon.
Make-up exams are not encouraged.
Attendance
I expect you to attend every lecture for the full amount of time that it is
scheduled. You will be held responsible for all of the material covered in the
course regardless of whether or not you were in attendance when it was presented.
Additionally, you will be held to the due dates and changes to exam schedule even
if you were not in class when it was announced. If you ever have to miss a class,
get the notes, handouts, and assignments as soon as possible from one of your
fellow students. Because there is no text for this course, it is critical that you have
the notes.
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Withdrawal Policy
You may withdraw from the course without a grade through February 18. If a
student has not officially dropped the class, they will be given a letter grade for the
course at the end of the term.
Academic Dishonesty
Cheating and/or plagiarism will not be tolerated in this course. If you are caught
cheating or plagiarizing, reactions on my part can range from giving you an F for
the assignment or exam in question to recommending expulsion from the
Community College. The following excerpt is from “Code of Conduct” in the
Student Handbook:
PLAGIARISM/CHEATING
(1) Plagiarism is defined as the buying, borrowing, or stealing of written material for the
purpose of fulfilling or partially fulfilling any assignment or task required as part of the
student’s program of instruction at the college. Any student who plagiarizes shall be
subject to disciplinary action.
(2) Any student who aids or abets the accomplishment of such activity as defined in
subsection (1) above shall also be subject to disciplinary action.
(3) An instructor may take any and all reasonable action against any student who is
deemed to have been guilty of plagiarism or cheating. Course of action might include,
but not be limited to:
(a) student dropped from course without recourse;
(b) student suspended or dismissed from the college;
(c) case referred to civil action.
(4) An instructor taking action against any student for an act of academic misconduct shall
report such action to the Dean of Instruction and the Dean of Students as soon as
possible, but no later than five working days after the incident. Any student subject to
action of an instructor for a violation of this section may seek review of that action by
the Dean of Students, if such a request is submitted in writing within five working days
from the date of the complained-of action.
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Biology 265
Dr. Jeanine Kay-Shoemake
Winter 2011
Tentative Schedule of Lecture Topics
Month
Jan
day
3
Topic/Chapter
Introduction to Immunity- 2 types, White blood cells, cytokines.
Innate Immunity: Phagocytosis, Inflammation, Complement,
Interferons, NK cells
Jan
10
Aquired Immunity: Characteristics, Antigens, AMI and CMI
(functions and cells), MHC Ag, Lymphoid tissue, Cytokines.
Jan
17
Holiday- No Class
Exam 1 – Take exam online 1/16-1/22
Jan
24
Cellular Immune response (CMI): T cell types and functions,
MHC Ag, T cell activation, T cell mechanisms of destruction.
Exam 2- Take exam online 1/25-1/30
Jan
31
Humoral Immune response (AMI): Introduction
Feb
7
Humoral Immune response (AMI): Antibody molecules, Function
of antibody molecules, B cell activation
Feb
14
Holiday
Feb
21
AMI: Primary/Secondary response, Vaccination and Vaccines,
Clinical testing for antibody molecules, Immunodiagnostics and
Immunotherapeutics
Exam 3 – Take exam online 2/22-2/28
Mar
1
Immune Dysfunction- Overview, Autoimmunity
Mar
8
Immune Dysfunction- Allergic response, Immune deficiency
Mar
14
Exam 4 – Take online 3/8-3/14
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