List Analysis Projects
LiST ANALYSIS PROJECT: MNCH interventions for advocacy
Question:
What would the impact be on maternal, neonatal and child mortality if proven interventions were scaled
up or if new interventions were introduced in the 68 priority countdown countries?
Packages/Interventions of interest:
Each intervention was scaled up individually, thus the impacts are not packaged. If they were packaged
together, the lives saved would be smaller.
Proven interventions Targets
SBA/Facility Delivery*
BEmONC
CEmONC
Postnatal Visit
Exclusive breastfeeding (<6 months)
Clean water / improved sanitation**
ITN/IRS
Hib Vaccine
ORS+Zinc
Treatment for pneumonia
Treatment for malaria
Target coverage
60%
60%
60%
80%
80%
80%
80%
80%
80%
80%
80%
Note that interventions with high coverage must be maintained in order to ensure that additional lives are not lost (i.e. TT, DPT3, Measles vaccine
and Vitamin A supplementation)
* includes some increase in antenatal corticosteroids and antibiotics for pPRoM as well as some increase in both basics emergency obstetric care
and comprehensive emergency obstetric care.
** assumes only increases in improved water, not increased availability of piped water in the home.
New interventions Targets
Active management of the third stage of labor
MgSO4 (for pre-eclampsia)
Neonatal resuscitation
Kangaroo mother care
Injectible antibiotics for neonatal infections
Rotavirus vaccine
Pneumococcal vaccine
Zinc supplementation
Hand washing
LiST Version Used:
Version 4.0
Outputs of Interest:
Target
Coverage
60%
60%
60%
60%
80%
80%
80%
80%
80%
The outputs of interest were the percent reductions in the number of maternal deaths, neonatal deaths
and under-5 deaths.
Baseline Coverage Values
(Available for download along with the relevant projection files)
Results:
Improvement in coverage of several of the proven interventions can still have a large impact on
mortality. For children, increased coverage of exclusive breastfeeding to 80% for children less than 6 months of
age could reduce under-5 mortality by approximately 13% while if ORS and zinc were similarly rolled out in the
68 priority countries, an 11% reduction in under-five mortality could be achieved. For neonates, the single
intervention which could have the greatest impact would be Comprehensive emergency obstetric and neonatal
care (at 60% coverage), reducing neonatal mortality by 16%. This would also avert 42% of maternal deaths.
Among ‘new’ interventions, neonatal resuscitation, injectible antibiotics for severe neonatal infection
and hand-washing could also reduce mortality by a significant amount.