ACUTE-RENAL-FAILURE IN NEONATES - A PROSPECTIVE-STUDY
By:ALIDRESSY, HMAM (ALIDRESSY, HMAM); BASIT, OBA (BASIT, OBA); HAQUE, KN
(HAQUE, KN); ABDURRAHMAN, MB (ABDURRAHMAN, MB)
ANNALS OF SAUDI MEDICINE
Volume: 11
Issue: 3
Pages: 297-301
Published: MAY 1991
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Abstract
Babies admitted to a neonatal intensive care unit in whom acute renal failure developed
were studied prospectively to determine the etiology, course, and outcome of the disorder,
as well as the reliability of renal indices in distinguishing intrinsic from prerenal renal
failure. The incidence of neonatal acute renal failure was 3.6% (22/603). The most
frequent causes were hypotension (86%), respiratory distress syndrome (41%), sepsis
(32%), and asphyxia (27%). Half of the patients were born at less than 32 weeks' gestation
and had a birth weight of less than 1500 gm. There was intrinsic renal failure in 15
neonates and prerenal failure in seven. Renal indices (urine-to-plasma ratio of osmolality,
fractional excretional excretion of sodium, and renal failure index) were not reliable in
differentiating between intrinsic or prerenal failure. Mortality from renal failure was high
at 77%. Survivors of neonatal acute renal failure who had no underlying congenital
anomalies of the urinary tract did not appear to exhibit residual renal impairment during
follow-up evaluation. It is important to identify those clinical indices that can be used in
determining the diagnosis and prognosis of acute renal failure in neonates, particularly in
very premature, low-birth-weight babies.
Keywords
Author Information
Addresses:
[ 1 ] KING SAUD UNIV, KING KHALID UNIV HOSP, DEPT PEDIAT, RIYADH, SAUDI ARABIA
Organization-Enhanced Name(s)
King Khalid University Hospital
King Saud University
Document Information
Document Type:Article
Language:English
Accession Number: WOS:A1991FN64100011
PubMed ID: 17588107
ISSN: 0256-4947