Functional prediction of genes associated with rMPs.
A). The top five ranking gene ontology (GO) terms associated with genes located in rMP regions. The
annotation of only selected species is shown here.
Top 5 ranking GO Term Name
Aaeg
protein binding
membrane
integral to membrane
intracellular
nucleotide binding
Cqui
nucleus
DNA binding
integral to membrane
zinc ion binding
nucleotide binding
Agam
protein binding
intracellular
membrane
integral to membrane
nucleotide binding
Dmel
nucleus
protein binding
zinc ion binding
DNA binding
integral to membrane
Amel
protein binding
regulation of transcription,
DNA-dependent
sequence-specific DNA binding
transcription factor activity
nucleus
sequence-specific DNA binding
Tcas
protein binding
integral to membrane
membrane
cytoplasm
intracellular
No of genes
68
40
35
28
27
30
28
23
20
19
168
96
91
87
83
431
245
219
184
177
18
9
9
7
7
5
4
4
2
2
B). A select list of A. aegypti genes (conserved hypothetical protein genes excluded) those are associated
the GO term ‘protein binding’. These are subset of genes those are identified in rMP regions in the
genome.
Gene_ID
AAEL000242
AAEL000707
AAEL001127
AAEL001227
AAEL001874
AAEL002317
AAEL003391
AAEL005284
AAEL005519
AAEL005661
AAEL006082
AAEL006261
AAEL006939
AAEL007288
AAEL007544
AAEL008058
AAEL008236
AAEL008426
AAEL008914
AAEL009458
AAEL009812
AAEL010328
AAEL011480
AAEL012493
AAEL012730
AAEL013063
AAEL013510
AAEL013539
AAEL013882
Gene_Description
voltage-gated potassium channel
cell cycle control protein cwf22
defective proboscis extension response, putative
sidestep protein
cop9 complex subunit
Insulin-like receptor Precursor (MIR)(EC 2.7.10.1)
tankyrase
receptor tyrosine phosphatase type r2a
synaptotagmin-14
defective proboscis extension response, putative
transcription initiation factor TFIID subunit 1
defective proboscis extension response, putative
smaug protein
dynamin
serine/threonine-protein kinase chk2 (cds1)
liprin alpha (lar-interacting protein alpha) (synapse defective protein 2)
sidestep protein
broad-complex core-protein
PHD finger protein
syntaxin 4,
type II collagen, putative
cAMP-dependent rap1 guanine-nucleotide exchange factor
tpr repeat nuclear phosphoprotein
attractin
dbl
autophagy related gene
smaug protein
SH2/SH3 adaptor protein
tkr