Supporting Information
On the observation for the need of unusually high concentration of Cysteine and
Homocysteine to Induce Aggregation of Polymer stabilized Gold Nano Particles
C. Radhakumary and K. Sreenivasan*
Laboratory for Polymer Analysis, Biomedical Technology Wing, Sree Chitra Tirunal Institute
for Medical Sciences and Technology, Trivandrum -695012, India.
* Email: sreeni@sctimst.ac.in Phone 091- 471 -2520248, Fax. 091- 471- 2341814.
Legends to Figures and Table.
Figure S1. TEM of CH-AuNP-Cys NPs showing inter particle distance
Figure S2. TEM of Virgin CH-AuNPs
Figure S3. The SPR absorption patterns of CH-Au interacted with different concentration of Cys for 30 min (Inset
shows the corresponding photographic images)
Figure S4. TEM images of Citrate stabilized Au NPs (A).On interaction with Cysteine (B)
Figure S5. Absorption profiles of citrate stabilized AuNPs (black) and AuNPs on interacting with 100 ppm Cys (red)
Figure S6. UV-Visible absorption (inset, the photographic images) of CH-AuNPs on interaction with various amino
acids
Fig S7The SPR pattern of CH-Au on interacting with 500 µg of each of glutathione, mercapto acetic acid, Cys and
HCys (for 30 min)
Table S1. Calculated parameters Using DLVO theory
1
Figure S1. TEM of CH-AuNP-Cys NPs showing inter particle distance
Figure S2. TEM of Virgin CH-AuNPs
2
Figure S3. The SPR absorption patterns of CH-Au interacted with different concentration of Cys for 30 min (Inset
shows the corresponding photographic images)
Figure S4. TEM images of Citrate stabilized Au NPs (A) On interaction with Cysteine (B)
3
Figure S5. Absorption profiles of citrate stabilized AuNPs (black) and AuNPs on interacting with 100 ppm Cys (red)
Figure S6. UV-Visible absorption (inset, the photographic images) of CH-Au NPs on interaction with various amino
acids.
4
Figure S7. The SPR pattern of CH-Au on interacting with 500 µg of each of glutathione, mercapto acetic acid, Cys
and HCys (for 1h)
Table S1. The calculated parameters Using DLVO theory
S.No
Parameters
Values
1
Debye-Huckel length
2.78 nm
2
Vander Waal’s Force
8.3 x 10-22 J
3
Inter particle repulsive force
6.67 X 10-15 J
4
Inter Particle Distance
2.12 + 0.3 nm
5