Name:_________________________________
Date:_______
Sergeant System’s Immune System
Defense Team Webquest
The immune system is not located in a specific organ. It’s easiest to think of your body’s
immune system as a group of different types of cells and tissues that work together to protect
the body. Each cell is designed to perform certain functions, such as killing damaged or infected
cells, carrying messages, making antibodies or carrying away debris.
In addition to the above the immune system can identify what cells and substances belong to
the body and which do not belong or that are unhealthy.
TASK
Your mission is to research components in the immune system in order to analyze the
requirements for an effective defensive immune system. To gather your information refer to
the following website:
http://www.sepa.duq.edu/regmed/immune/immune_intro.html
PROCESS
The following parts of the immune system are what you will be responsible for:

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Skin
Histamine
Macrophage
T Cell
B Cell
Antibody
Vaccine
The reading guide that you will find on the following pages will detail the specific research you
need to find before you can develop your Employment Profile. Each of the cell parts or organ
are the members of your “immune defense system team” that will require a profile.
Applicant #1- The Skin
(Please check off when complete)
o
o
o
o
o
Go to the following website:
http://www.sepa.duq.edu/regmed/immune/immune_intro.html
Read the information
Click on the “General Mechanisms” link at the top of the web page and read this
information
Watch the video clip that is on the “
Answer the questions
1) Hair and mucus are some examples that can help protect your body. In particular, the
skin is our first defense against germs! Why is the skin a good defense mechanism for
the immune system?
_______________________________________________________________________
_______________________________________________________________________
_______________________________________________________________________
_______________________________________________________________________
2) What would germs do to the body if you didn’t have skin?
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_______________________________________________________________________
_______________________________________________________________________
_______________________________________________________________________
Applicant #2- Histamine
(Please check off when complete)
o
o
Reread the section titled “ General Mechanisms”
Answer the following questions
1) Histamines are an important chemical in the body. What is their purpose in the immune
system?
_______________________________________________________________________
_______________________________________________________________________
_______________________________________________________________________
_______________________________________________________________________
2) True or False? Circle your response. If it is false, rewrite the statement so it is true.
Histamines are released when the skin blocks germs from entering the immune system.
_______________________________________________________________________
______________________________________________________________________
Applicant #3- Macrophages
(Please check off when complete)
o
Reread the section titled “ General Mechanisms”
o
Draw the image below
1) The macrophage is a swallowing cell, it can engulf things though phagocytosis. Draw
what a macrophage looks like when it is eating bacteria.
Applicant #4 – T Cell
(Please check off when complete)
o
Reread the section titled “ General Mechanisms”
o
Answer the following questions
1) Why do some T Cells remain in the body even after successful getting rid of an intruder?
_____________________________________________________________________________
_____________________________________________________________________________
_____________________________________________________________________________
____________________________________________________________________________
2) Match the description in the left column with the letter of their answers on the right.
Match
Descriptions
Answers
1. T cells are a type of
a. Intruder organisms
white blood cell
and infected cells
called_____.
2. This type of T Cell
b. Killer T Cell
can tell if another
cell is infected or
not
3. This type of T Cell
c. lymphocytes
carries information
and decides when
to tell other
immune cells to
carry out an
immune response
4. When a Killer T Cell
d. Specific
decides that a cell
is unhealthy it can
destroy it
with______.
5. T Cells can identify
e. Helper T Cell
individual germs
because they
are________.
6. To be able to do
f. enzymes
their job properly, T
cells must learn to
only attack_______
Applicant #5 – B Cell
(Please check off when complete)
o
o
o
Click the “ B Cells Link at the top of the web page
Read the information
Answer the following questions:
1) The B Cell is a special kind of swallowing cell. What do swallowing cells do?
_____________________________________________________________________________
_____________________________________________________________________________
_____________________________________________________________________________
____________________________________________________________________________
2) What is the B cell’s main job as a part of the immune system?
_____________________________________________________________________________
_____________________________________________________________________________
_____________________________________________________________________________
3) True or False? Circle your response. If false, rewrite the statement so it is true.
The receptor site is a very important part of the B cell- it is called an antibody. This receptor
site is a specific binding site on the membrane of the B cell, which means it can bind to many
different kinds of harmful particles.
_____________________________________________________________________________
_____________________________________________________________________________
_____________________________________________________________________________
Applicant # 6- Antibodies
(Please check off when complete)
o
Click the “ B Cells Link at the top of the web page
o
Read the information
o
Answer the following questions:
1) Circle the True Statement from each pair below:
Antibodies are produced by B
cells
The antibodies of one B cell
can bind many kinds of many
particles
B Cells release antibodies all
the time
OR
OR
OR
Antibodies are produced by T
Cells
The antibodies of one B cell
can bind to only one kind of
harmful particle
B cells only release antibodies
after becoming plasma B cells.
2) How do antibodies work? Explain.
_____________________________________________________________________________
_____________________________________________________________________________
_____________________________________________________________________________
_____________________________________________________________________________
Applicant # 7- Vaccine
(Please check off when complete)
o
Click the “ B Cells Link at the top of the web page
o
Read the information
o
Answer the following questions:
1) We get vaccines all the time. What is a vaccine?
_____________________________________________________________________________
_____________________________________________________________________________
_____________________________________________________________________________
2) True or False: If it is incorrect rewrite the explanation:
A vaccine exposes your immune system to a live virus or bacteria so that your B cells will create
the specific antibodies. So if you come in contact with them, your B cells will attack so you
won’t get sick.
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_____________________________________________________________________________
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Employment Profile
Directions: For each job within the immune system you will refer to your research
that you gathered from the website on the previous pages. This will help you to
complete an employment profile/ summary of the role that each plays in the
immune system. The following need to be a part of your profile; you will need to
complete six in total. Antibody has already been done for you.
•
Skin
•
Histamine
•
Macrophage
•
T Cell
•
B Cell
•
Antibody
•
Vaccine
Employment Profile Sample:
( You can draw a picture or select an image from the internet)
Name of New Employee: Alexander Antibody
Job Title: Arresting Officer
Job Description: Mr. Antibody is also known as a receptor. He helps a B cell recognize an
intruder in the body. Mr. Antibody will stick to this intruder and will hold it “under arrest”. This
happens so the intruder cannot move or multiply to make more intruders (pathogens).
(In the job description any specific roles or jobs can be explained for this section)
Name:___________________________________________
Name:___________________________________________
Image or drawing
Employment Profile
Name of New Employee: __________________________________
Job Title: ______________________________________________
Job Description:
__________________________________________________________________
__________________________________________________________________
__________________________________________________________________
__________________________________________________________________
__________________________________________________________________
__________________________________________________________________
__________________________________________________________________
__________________________________________________________________
__________________________________________________________________
__________________________________________________________________
__________________________________________________________________
__________________________________________________________________
_________________________________________________________________
Conclusion:
Now that you have completed the webquest and profiled your “ Immune Defense System
Team” you have gained insight as to how the immune system functions to maintain
homeostasis.
Evaluation:
Category
Teamwork
4 Excellent
3 Good
2Average
1 Needs Work
Partners are
supportive and
share the
responsibility 90%100% of the time.
No conflicts with
each other or
other classmates
Partners are
supportive and
share the
responsibility 70%79% of the time.
There were some
issues and conflicts
working together.
Partners are not
supportive and did
not share the
responsibility.
There were many
conflicts with each
other and or other
classmates.
WebQuest
Completeness
Sections 1-5 is
100% complete
Answer
Accuracy
90%-100% of the
answers are
correct.
Includes all of the
following:
New employee’s
name
Job title
Job description
which includes the
location in the
immune system.
Main role in the
immune system
Special jobs
Picture of
employee
Partners are
supportive and
share the
responsibility 80%90% of the time.
There were a few
conflicts working
together or with
other classmates.
Sections 1-5 is
85%- 99%
complete
80%-89% of the
answers are
correct.
Missing no more
than 2-3 of the
following:
New employee’s
name
Job title
Job description
which includes the
location in the
immune system.
Main role in the
immune system
Special jobs
Picture of
employee
Sections 1-5 is
70%- 84%
complete
70%-79% of the
answers are
correct.
Missing 4-6 of the
following:
New employee’s
name
Job title
Job description
which includes the
location in the
immune system.
Main role in the
immune system
Special jobs
Picture of
employee
Sections 1-5 is less
than 69%
complete.
less than 69% of
the answers are
correct
Missing all of the
following:
New employee’s
name
Job title
Job description
which includes the
location in the
immune system.
Main role in the
immune system
Special jobs
Picture of
employee
Employment
Profile
Evaluation
Source: Adapted from http://sepa.duq.edu/regmed/immune/immune_intro.html. 1/25/16