coagulopathy made easy
Dr.Ali Ahmad
KBA
PGY2
the pathways
high ptt
Heparin effect
The Correction
The Inhibitor effect
causes of high ptt
DIC
heparin therapy
factors deficiencies ( 11.10.9.8 )
inhibitors such as LA . ACL .
VWD .hemophilia .
high PT and INR
warfarin therapy
factors dependent of vit K
liver
DIC
clinical scenario
30 y old male obese known to have thrombosis
with PE on warfarin . admitted due to mild
bleeding per rectum .
my anticoagulated pt is bleeding
HASHTI .
1-Hold
2-Antidote
3-Support
4-Hemostatic measures
5-Transfusion
6-Investigate
level of urgency .
antidotes
high PT
hi
vit K
FFP
prothrombin complex concentrates
recombinant factor 7
what to do
clinical scenario
46 years old pt taking clexane for DVT
prophylaxis . know D/A admitted with LL
fracture need urgent surgery .
antidotes
protamine sulfate .
Fresh frozen plasma .
how to do it
how to do it heparin
THANKS
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God bless medicine
So others may live