Charge:
• Your task is to develop core ideas/projects for an $8-10M
($1.25-1.5M per year for 5 years) NIH Center proposal.
• Specifically, you should consider the following questions
Molecular Imaging
• Group Members
Peter A. Dowben
Yuri L, Lyubchenko
Xiao Cheng Zeng
Ron Cerny
Stephen DiMagno
Michael Boska
Briefly describe the core projects your group
would design for the Center. Please dream big.
• We envision a comprehensive center that spans molecular biology,
target identification, whole cell studies, small animal, large animal,
human imaging.
• Key new components of the facility include: centralized cell culture
facility, an adjacent animal facility, cyclotron, preclinical PET/CT
scanner, whole body MRI, small animal fluorescence scanner, imaging
mass spectrometer.
• Magnetic and electric dipolar molecules with functionalities not only
as MRI agents BUT also magnetocaloric and inductive heating and
cooling; nanoimaging characterization of the MRI agents; imaging
liqand-protected metal nanoparticles, PET, radiochemistry facility
(cyclotron).
• “Donor’s Name” Institute for Translational Molecular
Imaging
Identify the key faculty from from both
campuses to involve in these projects. Include
their strengths. (UNMC on next slide)
•
UNL Faculty
Strengths
A. Gruverman
Wai-Ning Mei (UNO)
R. Sabirianov
(UNO)
L. Parkhurst, UNL
D. Sellmyer, UNL
ferroelectrics
electronic structure theory
electronic structure theory
Chemistry, fluoresence
Physics, metal nanoparticles
synthesis
Mech. Eng., nanoparticle
characterization
18F Radiotracer synthesis
J. Shield, UNL
Stephen DiMagno
Chemistry (UNL)
Electrical Engineering (UNL)
Biomedical Engineering (UNL)
Identify the key faculty from from both
campuses to involve in these projects. Include
their strengths.
•
UNMC Faculty
Liu, Yutong
Boska, Michael
Sajja, Bala
Eppley Cancer Institute (UNMC)
Neurosciences (UNMC)
Cardiology (UNMC)
Radiology (UNMC)
College of Pharmacy (UNMC)
Strengths
MRI applications, Image processing
MRI applications
Image processing
Molecular Biology/target ID
Moleuclar/histology/animal models
Etc
Identify external academic partners & expertise
or equipment resources/strengths that are
needed to accomplish these projects.
Dana Farber Cancer Institute
U. Missouri Medical Center
Free University of Berlin (Institute for Inorganic Chemistry, Physical
Chemistry, FU Medical Center)
University of Minnesota
List potential industry/foundation partners
(think broadly) and what they would contribute.
Include reasons why they would be interested.
Thermo Fischer Scienticfic Health Care
GE Health Care
Sigma Aldrich
Epichem
Luna Nova
Cardinal Health
Siemens
Describe how you would link the Center to
other campus resources.
•
•
•
•
MRI facilities
Nanoimaging core facility, UNMC
Nanoscience facility, UNL
Mass Spectrometry facility, UNL