Summary of Glycolysis and Gluconeogenesis
Activation of Glucose for Biosynthesis
The nucleotide labels are used
to mark sugars set aside for
biosynthetic process
Formation of NDP-glucose
NTP + Glucose-1-phosphate
NDP-Glucose + PPi
(pyrophosphorylase)
Hydrolysis of Pyrophosphate
-Provides the energy that shifts the equilibrium to the right
Glycogen Synthesis
Production of Milk and Lactose
For antibody production
-Galactosyl transferase and -Lactoalbumin are components
of lactose synthase
Synthesis of Sucrose
Regulation of Carbohydrates
cAMP-dependent
Protein kinase
Conversion to ‘a’ is
positively modulated
by Glu-6-Phosphate
Phosphofructokinase
Substrate Cycles
Reaction leads to production of heat from ATP hydrolysis
-If both enzymes were to be active at the same time?
Net Reaction: ATP + H2O
ADP + Pi + Heat