CDC’s Health Protection Research Initiative Health Protection in the 21 Century

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CDC’s
CDC’s Futures
Futures Initiative
Initiative
CDC’s Health Protection
Research Initiative
st Century
Health Protection in the 21st
Achieving maximum health impact is the driving force
Two overarching health protection goals
– Health protection of people in all communities through
preparedness
• Infectious disease threats
• Environmental threats
• Terrorism threats
– Health protection through health promotion and
prevention of disease, disability and injury
• People in all communities will achieve their expected life
span with the best possible quality of life in every stag
Tanja Popovic, MD, PhD, FAAM
Acting Associate Director for Science
Centers for Disease Control and prevention
Death ….
Illness…
Public Health Research Workgroup – Phase I
Requests for Applications FY2004
Health ….
Office of Public Health Research
Life ….
Public Health Research Workgroup – Phase II
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CDC’s
CDC’s Futures
Futures Initiative
Initiative
Areas of Emphasis
Public Health Research
Workgroup
Charge
Develop a set of strategic directions for CDCCDC-wide research agendaagendasetting process addressing the following:
• Research issues and needs that are priorities for CDC’s customers and consistent with
departmental policies for an intraintra-agency stewardship of the health research enterprise
• Ways in which CDC needs to adapt its current practices in conducting and supporting
public health research
• Assurance that CDCCDC-sponsored research is being effectively applied by practitioners and
policymakers
Input
Guiding Principles
• Public health research agenda needs to be developed in
concert with the agency’s overall health protection goals.
Public Health Research
Workgroup deliberations
Outside-in approach:
meetings
conferences
consultations
Fast Track Process
&
Fast track Meeting
• Gaps in knowledge needed to achieve those goals will be
primary driver of research agenda.
• Research agenda will be set with external participation.
Other FI Workgroups
Excellence in Science Committee
Public Health Research Workgroup
Options and Recommendations
Key Strategic Issues
Strategic Direction for
AgendaAgenda-setting Process
Consultancies with Dr. Gerberding
& CDC senior staff
Agenda-setting Process
Agenda
Agenda-setting
Step 1. Develop a broad public health research framework
Step 2. Generate a list of possible research priorities
Step 1
Public Participation
Option 1
Option 2
Option 3
Step 3. Obtain input from broad range of outside groups and CDC
staff
Step 4. Synthesize input and generate a draft agenda
Step 5. Obtain broad public review of draft agenda
Level of Specificity
Criteria
Step 2
Step 3
Step 4
Step 5
Step 6
Step 6. Revise and finalize document
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Step 1.
Research-toResearch
to-practice Cycle
Research-to-practice
Level of Specificity
Levels
• Attempts to consider research needs which might
arise in each of several phases of the PH approach
to population health problems
• Early phase – problem identification and search for
causes
• MidMid-phase – design and implementation of
interventions
• Late phase – evaluation
Disease, Injury or
DisabilityDisability-related
CrossCross-cutting topics
1. Broadest
Chronic diseases
Genomics
2. Very broad
Cancer
Public health genomics
3. Broad
Breast cancer
Genetic screening
4. Specific
Effectiveness of
interventions to prevent
breast cancer
Effectiveness of family
screening programs
5. Very
specific
Effectiveness of
mammography
Effectiveness of computercomputerbased family screening
programs
6. Most
specific
Effectiveness of
mammography in women
4040-49 yrs of age
Effectiveness of computercomputerbased family screening
programs among Medicaid
populations
Public Participation
•
Breadth of participation: How broad? Who plays?
-- health organizations considered as
traditional partners
-- new health and nonnon-health related
organizations
-- lay representatives from communitycommunity-based
individual public
•
Depth of engagement: How intense? At what level?
level?
-- inform
-- consult
-- involve
-- collaborate
-- empower
CDC Public Health Research Agenda
for FY 2004
Criteria
Option 1.
Core set of criteria linked to CDC’s mission
-- public health need
-- potential impact
-- relevance
Option 2.
Option 1
and widely accepted national goal
-- reduction of health disparities
and widely accepted unmet need
-- crosscross-cutting across the CIOs
Requests for Application
(RFAs) for FY 2004
Overall goal for all RFAs is to influence priority health
protection research addressing the following:
Health protection of all people in all communities through
preparedness for
• Infectious disease threats
• Environmental threats
• Terrorism threats
Health protection through health promotion and prevention of
disease, disability and injury assuring that:
Expert Panel
“Fast Track” Meeting
• People in all communities will achieve their expected life span with
the best possible quality of life in every stage
November 2003
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Career Development (KO1)
(KO1)
InvestigatorInvestigator-initiated (RO1)
$ 14M for 2020-40 grants
$ 10M for 2020-30 grants
Purpose
To support investigatorinvestigator-initiated public health research projects that
have a high probability of influencing priority public health research.
research.
Research objectives
•This year priority is given to research that identifies innovative costcost-effective health
promotion policies, programs and activities in the workplace or that affect the
workplace.
•Future funding cycles will expand this initiative to address health protection research
relevant to other populations and sectors.
Strategy
Purpose
To support intensive supervised career development experience for
for researchers
in a variety of disciplines engaged in all types of public health
health research that have
a high probability of influencing priority public health issues.
Research objectives
To develop qualified, experienced, and sustainable cadre of independent
independent public
health researchers to support nation’s and CDC’s public health priorities.
priorities.
Design and evaluation of interventions and identification of determinants
determinants affecting the
successful implementation of evidenceevidence-based costcost-effective interventions in the
workplace or that have impact on the workplace.
Institutional Training
Career Development (KO1) and
Institutional Training
Strategies
$ 4M for 22-4 grants
Etiology and needs
Social, ecologic and developmental determinants of health
Determinants of individual behaviors that impact health
Assessing impact of social trends on population health needs
Purpose
Prevention
To develop or enhance training opportunities for individuals, selected
selected by the
institution, who are training for careers in specified areas of public health
research that that have a high probability of influencing priority
priority public health
issues.
Determinants of successful implementation of evidenceevidence-based interventions
Reduction of health disparities
Effectiveness of communitycommunity-based interventions
Application of genetic information to population health
Research objectives
To ensure a continuing supply of wellwell-trained scientists prepared to lead efforts
in conducting cuttingcutting-edge public health research.
Methods and Infrastructure
Impact of infrastructure and policy alternatives on health outcomes
outcomes
Economic factors and health
Improved surveillance methods
Early detection of public health risks
Communication strategies
Workforce needs and training issues
Centers of Excellence in
Health Promotion Economics
$ 1M for 1 grant
Purpose
To develop institutional capacity in Heath Promotion Economics.
Research objectives
To explore economic barriers, priorities, solutions and impact (including
(including costcosteffectiveness) of developing, evaluating and implementing health promotion
guidelines, recommendations, policies and programs to prevent disease,
disease, injury
and disability so that all people can achieve their expected life
life span with the best
possible quality of health at every life stage.
Strategies
Linking key academic, public and private entities across disciplines
disciplines
Conducting and facilitating Health Promotion Economics research
Providing Health Promotion Economics training.
training.
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Office of Public Health Research
A. Research Oversight, Strategy, and
Evaluation
A. Research Oversight, Strategy, and
Evaluation
1. Establish Public Health Research Priorities
2. Develop a Balanced Research Portfolio
• Establish and maintain CDC research
agenda
• Facilitate research agenda processes
• Translate agenda into strategic plan for
research
• Translate strategic CDCCDC-wide goals into
scientific goals
• Ensure balance of research between
intramural and extramural
• Build focus on outcomes into research
planning process
5
A. Research Oversight, Strategy, and
Evaluation
3. Evaluate Research Progress and Outcomes
•
•
•
•
Work on developing evaluations
Quality – Use of peer review
Relevance – Conduct relevance review
Performance – Track research
outcomes. Develop research metrics
B. Extramural Research and Peer
Review
• Develop scientific policy for CDC extramural
research and peer review
• Provide guidance on extramural issues
• Develop centralized peer review capabilities
• House CDCCDC-wide crosscross-cutting grants program
Futures Initiative Stage II:
Implementation Teams
• The Organizations Design
How we can work faster; be more connected across our agency and
with our partners; how we can better respond to our customers
needs
• The Health Protection Goals
• The Strategic Imperatives
Public
Health
Research
Implementation
Team
Implementation of recommendations form
the initial 4 Workgroups
• The Business Services Improvement
Improve our business practices and help create performanceperformance-based
culture at CDC
Two Component Team Structure
Core •
Team •
•
Leadership for overall effort
Specific charge to Action Teams
Responsible for action implementation
Action
Team
Action
Team
•
•
Propose innovative programs
and initiatives that support
workgroup recommendations
Present best ideas and
Action
collaborate with other Action Teams
Team
and the Core Team to arrive
at “best in class” programs and initiatives
Major Charge
Action
Team
Core
Team
Action
Team
• Defining public health research agenda and
coordination with the agency’s overall health
protection goals
• Implementation of agenda
- setting process
Action
Team
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CDC ‘treasures”
Social determinants of health
Workforce
Scientific creativity
and synergy
Information technology and
systems to support science
Measuring the impact of
research
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http://www.cdc.gov/futures
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