Affective Disorders

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Affective Disorders

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DEPRESSION

Affective (Emotional)

- Loss of interest/pleasure

- Worthlessness

- Guilt

Behavioral

- Passivity

- Lack of initiative

Cognitive (Thinking)

- Difficulty concentrating

- Negative thoughts

- Misplaced blame

- Low self-esteem

- Hopelessness

- Indecisiveness

Somatic (Physical)

- Insomnia/hypersomnia

- Appetite change

- Weight loss/gain

- Loss of energy

- Low libido (sex drive)

Symptomology

Client must present one A list symptom and at least 4 others:

A LIST SYMPTOMS:

Depressed mood

Loss of interest in activities that used to be enjoyed

B LIST SYMPTOMS:

Insomnia/hypersomnia

Appetite change

Loss of energy

Feeling worthless

Difficulty concentrating

Suicidal thoughts

Symptomology

Major Depressive

Disorder

 what we normally think of!

Dystemia

‘lite’ depression

Seasonal Affective

Disorder (S.A.D.)

 winter = 

Bipolar Disorder-

½ depression, ½ mania..

Different types!

TYPES

AT RISK POPULATIONS

2-3x more common in women

15% of the population is depressed at one point in their lifetime

 Higher in lower economic bracket

Higher in Jewish males (= to women)

17 million Americans a year

PROGNOSIS

Reccurent in 80% of those who experience at least one depressive episode

Average of 4 episodes

Prevalance Rates

Role of Genetics

Moffit (2006): followed 1000+ NZ subjects from 1972-2006. Recorded life stressors. Looked at LONG vs SHORT serotonin transporter gene

(5-HTT)

Depression after 4+ stressful experiences in 5 years:

33% with short gene depressed

17% with long gene depressed

So… Long gene works BETTER!

 Role of Neurotransmitters

↓ serotonin = ↑ chance of depression

Role of Hormones

Diathesis Stress Model

Stress releases the hormone CORTISOL, which is linked with depression

Vulnerability (genes, prenatal effects) + STRESS = ↑ chance of depression

Biological Etiology (Cause)

Role of Cognitions

Thoughts of hopelessness, pessimistic thinking, low self esteem.

Depresses cognitions, cognitive distortions, and irrational beliefs produce disturbances in mood.

Alloy (1999)

Followed Americans in their twenties. Thinking style was tested and students were placed into positive or negative thinking groups

After 6 years, only 1% of those in the positive thinking group had developed depression, 17% of the negative thinking group

Cognitive Etiology

Thoughts

Feelings Actions

Role of Culture

Individualistic Cultures: value the individual over the group

Symptoms: sad, hopeless, worthless, loss of interest

Collectivist Cultures: value the group/whole over the individual

 Symptoms: headache, tired, stomachache, backache

Sociocultural Etiology

Drug Therapy

Types of medication

Mood stabilizers- help even out highs/lows

Antidepressants- help lift the symptoms of depression

Antipsychotics- primarily treat symptoms of mania

Thase (2003)

Meta-analysis of 7 clinical trials looking at remission of depression rates

SSRIs (Prozac) = 35%

SNRI (Effexor) = 45%

Placebo = 25%

Significance: placebo effect almost as effective! We haven’t perfected antidepressants…. 

Treatment Options: Biological!

Electroconvulsive Therapy (ECT)

Applies a small amount of electrical current to the brain

Causes mild seizures, which changes brain chemistry

Effective in treating SEVERE depression

Controversial!!

Side effects- confusion and memory loss

Treatment Options: Biological!

Cognitive Behavioral Therapy (CBT)

Combines cognitive and behavioral therapy

Goal: change the automatic thoughts that contribute to negative emotions

Cognitive Therapy:

Focuses on how thought affect emotions and behaviors

Behavioral Therapy:

Concentrates on changing a person’s reaction to challenging situations

Hollon (2005)

Patients relapsed when stopped meds = 76%

Patients relapsed when given CBT = 31%

 Significance:

CBT helps people learn to COPE

Medicine covers symptoms, doesn’t cure/treat the CAUSE.

Treatment Options: Cognitive!

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