PNS sensory/afferent division, PNS efferent/motor division, nervous sytem pathways
What does the PNS afferent/sensory division consist of?
receptors and first order neurons
what do receptors of the afferent division of the PNS do? How are they categorized?
detect changes in environment
classified by: Location, Type of stimulus received, Structure of Receptor (general senses only)
What are the 3 different locations PNS receptors can be? What do they do at each location?
- exteroceptors: stimulus in external environment so receptors at body surface (e.g. touch, special senses)
- interoceptors: stimulus in internal environment (in viscera, blood vessels, etc.)
- proprioceptors: located in joints, skeletal muscles, etc. that monitor body position (stretch receptors, muscle spindles ) – balance and movement
What are the types of stimulus PNS receptors can detect (stimulus categories)?
- mechanoreceptors: mechanical stimuli (e.g. pressure, touch, hearing)
- thermoreceptors: temperature
- chemoreceptors: chemical
- photoreceptors: light
- nociceptors: pain
What are the 2 different structures of PNS receptors (general sense only)?
- free nerve endings: terminal dendrites of unipolar sensory neurons e.g. pain, root hair plexus
- encapsulated nerve endings: terminal dendrites enclosed in CT e.g. Meissner’s and Pacinian corpuscles
What are first order neurons?
unipolar neuron attached to or associated with receptor (may be encapsulated)
axon travels in cranial/spinal nerves to CNS
What do first order neurons have cell bodies in?
cell bodies in:
- sensory ganglia of cranial nerves
- dorsal root ganglia of spinal cord
What do first order neurons have axon terminals in?
axon terminals in:
- brain
- dorsal horn of spinal cord
What is the general vague path of the afferent PNS division?
stimulus to receptor to Central Nervous System (CNS)
What is the general vague path of the PNS motor division?
Central Nervous System (CNS) to Effector
What are the two subdivisions of the PNS motor division?
somatic and autonomic
What is the effector of the somatic and autonomic subdivisions?
somatic: skeletal muscle
autonomic: smooth muscle, cardiac muscle, glands
What cells does the somatic subdivision consist of? Where does it have cell bodies?
- consists of lower motor neurons: single multipolar neuron
- cell bodies in ventral horn of spinal cord to effector
- cell bodies in motor nuclei of brainstem to effector (e.g. facial motor nucleus for CN VII)
What cells does the antonomic subdivision consist of? Where does it have cell bodies?
2 successive multipolar neurons from CNS to effector:
1. preganglionic neuron: myelinated, cell body in brain stem or lateral horn of spinal cord
2. postganglionic neuron: unmyelinated, cell body in autonomic ganglion (outside CNS)
What is the path of the 2 successive multipolar neurons from CNS to effector?
What are the 2 subdivisions of the PNS autonomic division?
- Sympathetic (SNS)
- Parasympathetic (PSNS)
Where is the cell body of preganglionic neuron in SNS and PSNS of the autonomic division of PNS?
SNS: lateral horn (of T1-L2)
PSNS: brain stem and S2-S4
Where is the autonomic ganglia in SNS and PSNS of the autonomic division of PNS? (sns on left of answer)
What are the postganglionic neurons in SNS and PSNS of the autonomic division of PNS?
SNS: long axons
PSNS: short axons
What are the functions of the SNS and PSNS of the autonomic division of PNS?
SNS: fight or flight
PSNS: rest & digest
Where do the SNS and PSNS of the autonomic division of PNS exit the CNS (what nerves)?
SNS: mainly as thoracic nerves
PSNS: mainly (80%) as vagus nerve (cranial nerve X)
What are the 2 nervous system pathways
Ascending pathway (sensory) and descending pathway (motor)
What does the ascending pathway do?
- conducts impulses from general sense receptors into brain
- has 3 successive neurons from receptor to cortex
- axons of 1st and 2nd order neurons form ascending spinal tracts
What are the 3 successive neurons from receptor to cortex of the ascending pathway? What do they do?
- First Order Neuron: receptor to spinal cord (PNS)
- Second Order Neuron: interneuron, multipolar (CNS), cell body in dorsal horn of spinal cord or medulla (CNS), decussates (crosses over) in medulla
- Third Order Neuron: interneuron, multipolar, cell body in thalamus – impulses to postcentral gyrus (sensory cortex) (CNS)
What are the 3 different pathways/tracts of the ascending spinal tracts
- Dorsal (Posterior) Column Pathway/Tract
- Spinothalamic Pathway/Tracts
- Spinocerebellar Pathway/Tracts
What does the Dorsal (Posterior) Column Pathway/Tract do?
sensations can be precisely located (touch)
receptors = free nerve endings, Meissner’s etc.
What do the Spinothalamic Pathway/Tracts do?
non-specific, difficult to localize
receptors = temperature, pain
What do the Spinocerebellar Pathway/Tracts do?
ascending tracts from spinal cord to cerebellum
receptors = proprioceptors
2nd order neuron directly to cerebellum (no 3rd order): no conscious perception, no decussation
What does the descending pathway do?
- conduct impulses from brain to effector
- 2 neuron pathway
- axons of upper motor neurons form descending spinal tracts
What are the two neurons of the 2 neuron pathway of the descending pathway?
- Upper Motor Neuron (CNS): multipolar interneurons, cell bodies in cortex or brainstem nuclei
- Lower Motor Neuron (cell bodies in CNS and axons in PNS)
What tracts form the descending spinal tracts?
corticospinal tracts and indirect tracts
What are the corticospinal tracts?
cell bodies in cerebral cortex
tracts mainly decussate in medulla
What are the indirect tracts?
cell bodies in brainstem nuclei
receive impulses from motor cortex, basal nuclei, cerebellum