Spinal cord, PNS structures
What is the general structural over view of the spinal cord?
location: foramen magnum to L1/L2 (conus medullaris)
nerves continue down from spinal cord through vertebral foramina as cauda equina (horse’s tail) and exit at intervertebral foramina
filum terminale: a connective tissue extension of pia mater that anchors conus medullaris of spinal cord to coccyx
Where are CSF samples taken?
filum terminale in the spinal cord
What are the components of the cross-sectional structure of the spinal cord?
- anterior median fissure and posterior median sulcus: separate cord into right and left halves
- central canal: contains CSF
- Gray Matter
- White Matter
What does the Grey matter of the cross sectional structure of the spinal cord contain? What is its makeup?
- cell bodies and dendrites of motor neurons and interneurons
- H-shaped:
o cross bar = gray commissures
o horns: dorsal horn (sensory), lateral horn (motor), ventral horn (motor)
What does the white matter of the cross sectional structure of the spinal cord contain? What is its makeup?
myelinated axons containing ascending (sensory) or descending (motor) tracts
forms columns: dorsal column, lateral column, and ventral column
What are the functions of the spinal cord?
- sensory and motor impulses
- produces reflexes (fast, predictable, automatic responses to changes in environment e.g. withdrawal reflex)
What are the structures of the peripheral nervous system?
Cranial nerves and spinal nerves
What are the 12 pairs of cranial nerves?
What brain regions are associated with the 12 pairs of cranial nerves?
What cranial nerves are associated with the forebrain?
- olfactory and optic (1-2 of pneumonic)
- they are also the only neurons that are "only sensory neurons"
What cranial nerves are associated with the midbrain?
oculomotor and trochlear (3-4 of pneumonic)
What cranial nerves are associated with the pons?
trigeminal, abducens, and vestibulocochlear (5-8 of pneumonic)
What cranial nerves are associated with the medulla oblongata?
- 9-12 of pneumonic
- glossopharyngeal, vagus, accessory, and hypoglossal
What pair of cranial nerves are mainly sensory neurons?
vestibulocochlear (9 in pneumonic)
Where do motor and sensory neurons have their cell bodies?
- motor neurons have cell bodies in brainstem nuclei
- sensory neurons have cell bodies in ganglia of PNS
What are the motor and sensory fcns of the trigeminal nerve (5 in pneumonic)?
- motor function = chewing
- sensory function = conveys general sensations (touch, pressure, pain, temperature) from face to CNS
What are the 9 pairs of cranial nerves that carry both sensory and motor neurons?
oculomotor, trochlear, trigeminal, abducens, facial, glossopharyngeal, vagus, accessory, and hypoglossal
What are the 31 pairs of spinal nerves?
o 8 cervical
o 12 thoracic
o 5 lumbar
o 5 sacral
o 1 coccygeal
- all mixed nerves
Where do spinal nerves exit?
exit via intervertebral foramina (except 1st – between atlas and occipital)
What are the dorsol and ventral roots? How many points of attachment do they have to the spinal cord?
- Dorsal Root: sensory neurons; cell bodies in dorsal root ganglion
- Ventral Root: autonomic and somatic motor neurons; cell bodies in ventral or lateral horn
- 2 points of attachment
What does the spinal nerve do? What is it?
- joining of dorsal and ventral roots
- immediately divide into branches (rami): dorsal ramus, ventral ramus, and rami communicantes
What does the dorsal ramus do?
innervate skin and muscles of the back
What does the ventral ramus do?
forms thoracic nerves (T2 – T12) ) OR further branch and join up forming nerve plexuses (= nerve network)
What does the rami communicantes do?
connect ventral ramus (spinal nerve) to sympathetic trunk
contain autonomic nerve fibres (neurons)
What are the 4 spinal nerve plexuses? What spinal nerves are the formed by? What important nerves arise from them?
What is at the cross section of a nerve? What are the different kinds?
- CT wrappings:
- Epineurium: around whole nerve
- Perineurium: around fascicles
- Endoneurium: around axon and myelin
What important nerves arise from brachial plexus? Where is it?
What important nerves arise from sacral plexus? Where is it?