2023-03-16T21:15:16+03:00[Europe/Moscow] en true <p>tetracycline, doxycycline, minocycline</p>, <p>Tigecycline, Omadacycline, Eravacycline, Sarecycline</p>, <p>doxycycline, minocycline, omadacycline, tetracycline, </p>, <p>tigecycline, eravacycline</p>, <p>Sarecycline </p>, <p>d</p>, <p>d</p>, <p>chlamydia, genital tract infections, vibrio cholera, CA-MRSA, lyme disease, trench fever</p>, <p>doxycycline + AG; aids patients</p>, <p>complicated: skin infection, intra-abdominal infection</p>, <p>c</p>, <p>CABP, acute bacterial skin infection</p>, <p>tc efflux in gm +; ribosome protection</p>, <p>a</p>, <p>tc efflux in gm+ &amp; gm-; ribosome protection</p>, <p>eravacycline</p>, <p>sarecycline</p>, <p>complicated intra-abdominal infections</p>, <p>moderate-severe acne vulgaris</p>, <p>less active; less damage to GI flora</p>, <p>a</p>, <p>b,d</p>, <p>tigecycline, minocycline, doxycycline </p> flashcards
🪐🪐Tetracyclines (Drug Specific).🪐🪐

🪐🪐Tetracyclines (Drug Specific).🪐🪐

  • tetracycline, doxycycline, minocycline

    What are first generation tetracyclines?

  • Tigecycline, Omadacycline, Eravacycline, Sarecycline

    What are our second generation tetracyclines?

  • doxycycline, minocycline, omadacycline, tetracycline,

    Which Tetracyclines can be taken orally & IV?

  • tigecycline, eravacycline

    Which Tetracyclines can IV only?

  • Sarecycline

    Which Tetracycline can only be taken orally?

  • d

    Which tetracycline causes CNS SE's like vertigo & ataxia?

    a) tigecycline

    b) Omadacycline

    c) Doxycycline

    d) Minocycline

  • d

    Which tetracycline decreases the efficacy of oral contraceptives?

    a) doxycycline

    b) tetracycline

    c) minocycline

    d) demecyclocline

  • chlamydia, genital tract infections, vibrio cholera, CA-MRSA, lyme disease, trench fever

    Doxycycline is a 1st line treatment for what ?

  • doxycycline + AG; aids patients

    How do we treat Trench fever? Who is it a first line treatment for?

  • complicated: skin infection, intra-abdominal infection

    Tigecycline tx?

  • c

    Which tetracycline has a black box warning for increased risk of death?

    a) omadacycline

    b) seracycline

    c) tigecycline

    d) minocycline

  • CABP, acute bacterial skin infection

    Omadacycline tx?

  • tc efflux in gm +; ribosome protection

    What specific resistance mechanism does Omadacycline possess?

  • a

    Which tetracycline has a fluorine in it?

    a) eravacycline

    b) tetracycline

    c) minocycline

    d) demecyclocline

  • tc efflux in gm+ & gm-; ribosome protection

    What specific resistance mechanism does Eravacycline possess?

  • eravacycline

    Which tetracycline failed clinical trials in patients for complicated UTI?

  • sarecycline

    Which tetracycline has an unknown MOA?

  • complicated intra-abdominal infections

    Eravacycline tx?

  • moderate-severe acne vulgaris

    Sarecycline tx?

  • less active; less damage to GI flora

    What are pros & cons associated with Sarecycline?

  • a

    Which tetracycline has a glycylamido group?

    a) tigecycline

    b) Omadacycline

    c) Doxycycline

    d) eravacycline

  • b,d

    Which tetracycline has a trimethylamino group?

    a) tigecycline

    b) Omadacycline

    c) Doxycycline

    d) eravacycline

  • tigecycline, minocycline, doxycycline

    Which Tetracyclines are semi-synthetic?