2023-09-06T03:12:26+03:00[Europe/Moscow] en true <p>selective inhibitor of sterol absorption via NPC1L1; reduces cholesterol into cell; cell produces more LDL receptors </p>, <p>colestipol, cholestyramine, colesevelam</p>, <p>a large polymeric cation exchange-resin that prevents the reabsorption of bile acids; increases LDL receptor to bring cholesterol in and convert to bile </p>, <p>decreased compensatory response</p>, <p>digitalis, thiazides, warfarin, folic acid, aspirin, ezetimibe, pravastatin, fluvastatin, ascorbic acid </p>, <p>1h before; 2-4 h after</p> flashcards
Sterol Inhibitor & Bile inhibitors

Sterol Inhibitor & Bile inhibitors

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  • selective inhibitor of sterol absorption via NPC1L1; reduces cholesterol into cell; cell produces more LDL receptors

    Ezetimibe MOA?

  • colestipol, cholestyramine, colesevelam

    Which drugs are Bile acid sequestrants? (3)

  • a large polymeric cation exchange-resin that prevents the reabsorption of bile acids; increases LDL receptor to bring cholesterol in and convert to bile

    Bile Acid Sequestrant MOA?

  • decreased compensatory response

    Bile Acid Sequestrant +Stain =

  • digitalis, thiazides, warfarin, folic acid, aspirin, ezetimibe, pravastatin, fluvastatin, ascorbic acid

    Bile Acid Sequestrants impair the absorption of which drugs? (9)

  • 1h before; 2-4 h after

    How should additional medication be given when taking BAS?