2023-09-04T22:48:41+03:00[Europe/Moscow] en true <p>Open-label</p>, <p>factorial design </p>, <p>Composite endpoint</p>, <p>unpaired t-test</p>, <p>censoring</p>, <p>subgroup analysis</p>, <p>to identify similarities or differences in the magnitude of treatment effect among different categories of patients</p>, <p>the probability of dying or experiencing the event; given that patients have survived up to a given point in time</p>, <p>P- value</p>, <p>discrete variable</p>, <p>continuous variable </p> flashcards
Statistics (ACCORD trial)

Statistics (ACCORD trial)

  • Open-label

    -a trial that is not completely blinded, typically in that subjects and physicians have knowledge of the assigned treatment

  • factorial design

    -an experiment whose design consists of 2 or more factors, each with discrete values or "levels"

    -allows researchers to look at how multiple factors affect a dependent variable, both independently and together.

  • Composite endpoint

    - combining several events such as death, myocardial infarction, or stroke into a single study outcome.

  • unpaired t-test

    -a statistical procedure that compares the averages/means of two independent or unrelated groups to determine if there is a significant difference between the two

  • censoring

    -subjects who either die of causes other than the disease of interest or are lost to follow up

  • subgroup analysis

    - a type of analysis done by breaking down study samples into subsets of participants based on a shared characteristic

  • to identify similarities or differences in the magnitude of treatment effect among different categories of patients

    What is the purpose of a subgroup analysis?

  • the probability of dying or experiencing the event; given that patients have survived up to a given point in time

    What is the dependent variable in Survival Analysis?

  • P- value

    the probability of obtaining results at least as extreme as the observed results; assuming the null hypothesis is correct.

  • discrete variable

    a variable that takes on distinct, countable values. ex: judge ranking a performer 0-10.

  • continuous variable

    a variable that takes on any value within a range, and the number of possible values within that range is infinite.