2022-09-09T23:57:32+03:00[Europe/Moscow] en true <p>saturated solution</p>, <p>solubility</p>, <p>unsaturated solution</p>, <p>supersaturated solution</p>, <p>ionization </p>, <p>absorption, distribution, elimination</p>, <p>adjust pH so that drug is ionized</p>, <p>increase</p>, <p>decrease</p>, <p>So</p>, <p>S</p>, <p>Intrinsic solubility</p>, <p>Apparent solubility</p>, <p>diminishes solubility </p>, <p>slightly increases solubility</p>, <p>decreases; decreases dissociation of weak electrolyte by increasing pKa</p>, <p>Solubility Product (Ksp)</p>, <p>add citrate</p>, <p>add something that will remove another ion</p>, <p>Exothermic </p>, <p>Endothermic</p>, <p>True</p> flashcards
Solubility Concepts

Solubility Concepts

Customize
collection saved
Share
Long Term Learning Spaced Repetition
Add to Long Term Learning Desk
Fast learning Repeat this set of flashcards
Preview Test Spell
Play
Match
Review

  • saturated solution

    one in which solute is in equilibrium with the solid phase

  • solubility

    concentration of solute in a saturated solution.

  • unsaturated solution

    a solution in which drug is present below its solubility.

  • supersaturated solution

    contains more solute than a saturated solution.  It is very UNSTABLE and generally precipitation occurs with agitation, seed crystals, or scratching the container side.

  • ionization

    Solubility of weak electrolytes is affected by ____

  • absorption, distribution, elimination

    Which aspects of ADME does ionization affect in regards to solubility?

  • adjust pH so that drug is ionized

    How do you increase the solubility of weak electrolytes?

  • increase

    In regards to a weak acid, raising the pH will have what effect on its solubility?

  • decrease

    In regards to a weak acid, lowering the pH will have what kind of effect on its solubility?

  • So

    intrinsic solubility

  • S

    apparent solubility

  • Intrinsic solubility

    the solubility of the compound in its free acid or free base form.

  • Apparent solubility

    is the experimentally determined solubility of a solute in a solvent system and may be higher or lower than the equilibrium

  • diminishes solubility

    What is the common ion effect on solubility ?

  • slightly increases solubility

    What is the effect of not in common ions on solubility?

  • decreases; decreases dissociation of weak electrolyte by increasing pKa

    How does the addition of a co-solvent to water affect solubility & why?

  • Solubility Product (Ksp)

    is the product of the concentrations of each ion raised to a power equal to the stoichiometriccoefficient (number of ions appearing in the formula).

  • add citrate

    How do you increase solubility of iron?

  • add something that will remove another ion

    How do you increase solubility of slightly soluble salt?

  • Exothermic

    this reaction causes an increase in temperature and the heat released from this reaction causes a decrease in solubility.

  • Endothermic

    this reaction causes an increase in temperature, and more heat is absorbed; causing solubility to increase.

  • True

    Increasing unsaturation causes an increase in solubility in polar solvents. T/F?