Transformation of melanocytes may arise from preexisting nevus or de novo. Usually brown; can be tan, black, pink-red, purple, or
mixed pigmentation. Often irregular or notched borders. May have scaling, flaking, oozing texture. Risk factors are UV radiation from sun exposure
and indoor tanning, aging, and family history. In men, most melanomas are located on the trunk and back; in women most are on the legs and feet;
in older adults, most are on the head and neck.