2017-07-29T20:36:12+03:00[Europe/Moscow] en true Base pair, Genetic code, Chromatin, Meiosis, Stop codon, Argonaute, RNA interference, Heterochromatin, Messenger RNA, Biopolymer, Morpholino, Non-coding RNA, B3 domain, Free radical damage to DNA, Gemini Somatics, Noreen Murray, Baek Sung-hee, How to Clone a Mammoth, 100,000 Genomes Project, 100K Genome Project, Nucleic acid analogue, Transcription factor II F, CpG site, Transcription factor II E, Comparative Toxicogenomics Database, AT-hook flashcards
Molecular genetics

Molecular genetics

  • Base pair
    A base pair (bp) is a unit consisting of two nucleobases bound to each other by hydrogen bonds.
  • Genetic code
    The genetic code is the set of rules by which information encoded within genetic material (DNA or mRNA sequences) is translated into proteins by living cells.
  • Chromatin
    Chromatin is a complex of macromolecules found in cells, consisting of DNA, protein, and RNA.
  • Meiosis
    Meiosis /maɪˈoʊsᵻs/ is a specialized type of cell division that reduces the chromosome number by half, creating four haploid cells, each genetically distinct from the parent cell that gave rise to them.
  • Stop codon
    In the genetic code, a stop codon (or termination codon) is a nucleotide triplet within messenger RNA that signals a termination of translation into proteins.
  • Argonaute
    The Argonaute protein family plays a central role in RNA silencing processes, as essential catalytic components of the RNA-induced silencing complex (RISC).
  • RNA interference
    RNA interference (RNAi) is a biological process in which RNA molecules inhibit gene expression, typically by causing the destruction of specific mRNA molecules.
  • Heterochromatin
    Heterochromatin is a tightly packed form of DNA, which comes in multiple varieties.
  • Messenger RNA
    Messenger RNA (mRNA) is a large family of RNA molecules that convey genetic information from DNA to the ribosome, where they specify the amino acid sequence of the protein products of gene expression.
  • Biopolymer
    Biopolymers are polymers produced by living organisms; in other words, they are polymeric biomolecules.
  • Morpholino
    A morpholino, also known as a morpholino oligomer and as a phosphorodiamidate morpholino oligomer (PMO), is type of oligomer molecule (colloquially, an oligo) used in molecular biology to modify gene expression.
  • Non-coding RNA
    A non-coding RNA (ncRNA) is an RNA molecule that is not translated into a protein.
  • B3 domain
    The B3 DNA binding domain (DBD) is a highly conserved domain found exclusively in transcription factors, from higher plants (≥40 species) (Pfam PF02362) combined with other domains (InterPro: IPR003340).
  • Free radical damage to DNA
    Free radical damage to DNA can occur as a result of exposure to UV radiation or to radiomimetic compounds.
  • Gemini Somatics
    Gemini Somatics is a biotechnology company located in Riverside, Oregon, working primarily in the field of synthetic somatology, which is an emerging science developed by Dr Edward Darmos.
  • Noreen Murray
    Lady Noreen Elizabeth Murray (née Parker) CBE, FRS FRSE (26 February 1935 – 12 May 2011) was an English molecular geneticist who helped develop a vaccine against hepatitis B, the first genetically-engineered vaccine approved for human use.
  • Baek Sung-hee
    Doctor Baek Sung-hee (born 1970) is a South Korean scientist specialising in molecular genetics.
  • How to Clone a Mammoth
    How to Clone a Mammoth: The Science of De-Extinction is a 2015 non-fiction book by biologist Beth Shapiro and published by Princeton University Press.
  • 100,000 Genomes Project
    The 100,000 Genomes Project is a UK Government project that is sequencing whole genomes from National Health Service patients.
  • 100K Genome Project
    The 100K Pathogen Genome Project was launched in July 2012 by Bart Weimer (UC Davis) as an academic, public, and private partnership.
  • Nucleic acid analogue
    Nucleic acid analogues are compounds which are analogous (structurally similar) to naturally occurring RNA and DNA, used in medicine and in molecular biology research.
  • Transcription factor II F
    Transcription factor IIF (TFIIF) is one of several general transcription factors that make up the RNA polymerase II preinitiation complex.
  • CpG site
    The CpG sites or CG sites are regions of DNA where a cytosine nucleotide is followed by a guanine nucleotide in the linear sequence of bases along its 5' → 3' direction.
  • Transcription factor II E
    Transcription factor II E (TFIIE) is one of several general transcription factors that make up the RNA polymerase II preinitiation complex.
  • Comparative Toxicogenomics Database
    The Comparative Toxicogenomics Database (CTD) is a public website and research tool launched in November 2004 that curates scientific data describing relationships between chemicals/drugs, genes/proteins, diseases, taxa, phenotypes, GO annotations, pathways, and interaction modules.
  • AT-hook
    The AT-hook is a DNA-binding motif present in many proteins, including the high mobility group (HMG) proteins, DNA-binding proteins from plants and hBRG1 protein, a central ATPase of the human switching/sucrose non-fermenting (SWI/SNF) remodeling complex.