Hosam Mohamed-
osmoles/liter of solvent
Osmolarity =
-
osmoles/kg of solvent
Osmolality =
-
a
Which is a sugar alcohol?
a) mannitol
b) acetazolamide
c) methazolamide
d) dichlorphenamide
-
zinc metallo
Carbonic anhydrase is a _________ enzyme
-
c
Which is a non-competitive inhibitor?
a) mannitol
b) acetazolamide
c) methazolamide
d) dichlorphenamide
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d
Which has two sulfonamide groups?
a) mannitol
b) acetazolamide
c) methazolamide
d) dichlorphenamide
-
b
Which is a reversible inhibitor of CA?
a) mannitol
b) acetazolamide
c) methazolamide
d) dichlorphenamide
-
c
Which has a quinazoline ring?
a) chlorthalidone
b) indapamide
c) metolazone
d) HCTZ
-
a
Which has a Phthalimide ring?
a) chlorthalidone
b) indapamide
c) metolazone
d) HCTZ
-
b
Which also inhibits CA?
a) chlorthalidone
b) indapamide
c) metolazone
d) HCTZ
-
a,b
Which are the longest-acting?
a) chlorthalidone
b) indapamide
c) metolazone
d) HCTZ
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d
Which is the most potent?
a) ethacrynic acid
b) furosemide
c) torsemide
d) bumetanide
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covalent/irreversible binder to Cys93
Ethacrynic acid MOA?
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pteridine bicyclic ring; pyrimidine + pyrazine
What is the key functional group of triamterene?
-
b
Which is more potent?
a) triamterene
b) amiloride
