2023-09-09T01:38:03+03:00[Europe/Moscow] en true <p>b, d, e</p>, <p>e</p>, <p>a, c, f</p>, <p>open ring system</p>, <p>a</p>, <p>b</p>, <p>b</p>, <p>c</p>, <p>d</p>, <p>e</p>, <p>b</p>, <p>a,b</p>, <p>a,b</p>, <p>c</p>, <p>polyunsaturated </p>, <p>Lovaza</p>, <p>Epanova</p>, <p>Vascepa </p>, <p>a</p>, <p>b</p>, <p>c</p> flashcards
Med Chem of Dyslipidemia

Med Chem of Dyslipidemia

  • b, d, e

    Which are inactive lactone prodrugs?

    a) rosuvastatin

    b) lovastatin

    c) atorvastatin

    d) simvastatin

    e) mevastatin

    f) fluvastatin

  • e

    Which inactive statin DOESN'T contain a methyl group?

    a) rosuvastatin

    b) lovastatin

    c) atorvastatin

    d) simvastatin

    e) mevastatin

    f) fluvastatin

  • a, c, f

    Which contain a fluorine?

    a) rosuvastatin

    b) lovastatin

    c) atorvastatin

    d) simvastatin

    e) mevastatin

    f) fluvastatin

  • open ring system

    What structural difference is there between an "inactive" vs "active"

    statin?

  • a

    Which contains a beta-lactam ring NOT fused to another ring?

    a) ezetimibe

    b) cholestyramine

    c) colestipol

    d) colesevelam

    e) bempedoic acid

  • b

    Which contains a Quaternary Ammonium functional group?

    a) ezetimibe

    b) cholestyramine

    c) colestipol

    d) colesevelam

    e) bempedoic acid

  • b

    Which contains an inert styrene-divinylbenzene copolymer?

    a) ezetimibe

    b) cholestyramine

    c) colestipol

    d) colesevelam

    e) bempedoic acid

  • c

    Which is a copolymer of diethlenetriamine (DETA) or

    tetraethylenepentamine (TEPA)?

    a) ezetimibe

    b) cholestyramine

    c) colestipol

    d) colesevelam

    e) bempedoic acid

  • d

    Which is a modified polyallylamine?

    a) ezetimibe

    b) cholestyramine

    c) colestipol

    d) colesevelam

    e) bempedoic acid

  • e

    Which is a prodrug?

    a) ezetimibe

    b) cholestyramine

    c) colestipol

    d) colesevelam

    e) bempedoic acid

  • b

    Which is a benzophenone?

    a) Gemfibrozil

    b) fenofibrate

    c) niacin

    d) Vascepa

  • a,b

    Which are amphipathic?

    a) Gemfibrozil

    b) fenofibrate

    c) niacin

    d) Vascepa

  • a,b

    Which contain ketones?

    a) Gemfibrozil

    b) fenofibrate

    c) niacin

    d) Vascepa

  • c

    Which is a pyridine carboxylic acid?

    a) Gemfibrozil

    b) fenofibrate

    c) niacin

    d) Vascepa

  • polyunsaturated

    ALA, EPA, and DHA are __________ fatty acids.

  • Lovaza

    Omega -3 ethyl esters (EPA and DHA)

  • Epanova

    Omega-3 carboxylic acid

  • Vascepa

    Omega-3 ethyl-eicosapentaenoic acid (E-EPA)

  • a

    Which contains monacolin K (Lovastatin) ?

    a) red yeast rice

    b) garlic

    c) CoQ10

  • b

    Which lowers total cholesterol & LDL ?

    a) red yeast rice

    b) garlic

    c) CoQ10

  • c

    Which has an oxidized & reduced form?

    a) red yeast rice

    b) garlic

    c) CoQ10