b, d, e
Which are inactive lactone prodrugs?
a) rosuvastatin
b) lovastatin
c) atorvastatin
d) simvastatin
e) mevastatin
f) fluvastatin
e
Which inactive statin DOESN'T contain a methyl group?
a) rosuvastatin
b) lovastatin
c) atorvastatin
d) simvastatin
e) mevastatin
f) fluvastatin
a, c, f
Which contain a fluorine?
a) rosuvastatin
b) lovastatin
c) atorvastatin
d) simvastatin
e) mevastatin
f) fluvastatin
open ring system
What structural difference is there between an "inactive" vs "active"
statin?
a
Which contains a beta-lactam ring NOT fused to another ring?
a) ezetimibe
b) cholestyramine
c) colestipol
d) colesevelam
e) bempedoic acid
b
Which contains a Quaternary Ammonium functional group?
a) ezetimibe
b) cholestyramine
c) colestipol
d) colesevelam
e) bempedoic acid
b
Which contains an inert styrene-divinylbenzene copolymer?
a) ezetimibe
b) cholestyramine
c) colestipol
d) colesevelam
e) bempedoic acid
c
Which is a copolymer of diethlenetriamine (DETA) or
tetraethylenepentamine (TEPA)?
a) ezetimibe
b) cholestyramine
c) colestipol
d) colesevelam
e) bempedoic acid
d
Which is a modified polyallylamine?
a) ezetimibe
b) cholestyramine
c) colestipol
d) colesevelam
e) bempedoic acid
e
Which is a prodrug?
a) ezetimibe
b) cholestyramine
c) colestipol
d) colesevelam
e) bempedoic acid
b
Which is a benzophenone?
a) Gemfibrozil
b) fenofibrate
c) niacin
d) Vascepa
a,b
Which are amphipathic?
a) Gemfibrozil
b) fenofibrate
c) niacin
d) Vascepa
a,b
Which contain ketones?
a) Gemfibrozil
b) fenofibrate
c) niacin
d) Vascepa
c
Which is a pyridine carboxylic acid?
a) Gemfibrozil
b) fenofibrate
c) niacin
d) Vascepa
polyunsaturated
ALA, EPA, and DHA are __________ fatty acids.
Lovaza
Omega -3 ethyl esters (EPA and DHA)
Epanova
Omega-3 carboxylic acid
Vascepa
Omega-3 ethyl-eicosapentaenoic acid (E-EPA)
a
Which contains monacolin K (Lovastatin) ?
a) red yeast rice
b) garlic
c) CoQ10
b
Which lowers total cholesterol & LDL ?
a) red yeast rice
b) garlic
c) CoQ10
c
Which has an oxidized & reduced form?
a) red yeast rice
b) garlic
c) CoQ10